| Full name: nudix hydrolase 18 | Alias Symbol: FLJ22494|MTH3 | ||
| Type: protein-coding gene | Cytoband: 8p21.3 | ||
| Entrez ID: 79873 | HGNC ID: HGNC:26194 | Ensembl Gene: ENSG00000275074 | OMIM ID: 615791 |
| Drug and gene relationship at DGIdb | |||
Expression of NUDT18:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUDT18 | 79873 | 219665_at | -0.1499 | 0.5315 | |
| GSE20347 | NUDT18 | 79873 | 219665_at | -0.0018 | 0.9918 | |
| GSE23400 | NUDT18 | 79873 | 219665_at | 0.0783 | 0.1181 | |
| GSE26886 | NUDT18 | 79873 | 219665_at | 0.0739 | 0.8086 | |
| GSE29001 | NUDT18 | 79873 | 219665_at | 0.0253 | 0.9284 | |
| GSE38129 | NUDT18 | 79873 | 219665_at | 0.0092 | 0.9454 | |
| GSE45670 | NUDT18 | 79873 | 219665_at | 0.3556 | 0.0172 | |
| GSE53622 | NUDT18 | 79873 | 45073 | -0.1007 | 0.5274 | |
| GSE53624 | NUDT18 | 79873 | 45073 | -0.0869 | 0.4208 | |
| GSE63941 | NUDT18 | 79873 | 219665_at | -0.8149 | 0.0228 | |
| GSE77861 | NUDT18 | 79873 | 219665_at | 0.0890 | 0.7017 | |
| GSE97050 | NUDT18 | 79873 | A_23_P123454 | 0.0410 | 0.9029 | |
| SRP007169 | NUDT18 | 79873 | RNAseq | -0.9753 | 0.1174 | |
| SRP008496 | NUDT18 | 79873 | RNAseq | -0.6027 | 0.0990 | |
| SRP064894 | NUDT18 | 79873 | RNAseq | 0.1326 | 0.7042 | |
| SRP133303 | NUDT18 | 79873 | RNAseq | -0.3252 | 0.0831 | |
| SRP159526 | NUDT18 | 79873 | RNAseq | -0.6419 | 0.1116 | |
| SRP193095 | NUDT18 | 79873 | RNAseq | -0.4005 | 0.0038 | |
| SRP219564 | NUDT18 | 79873 | RNAseq | 0.1503 | 0.7840 | |
| TCGA | NUDT18 | 79873 | RNAseq | -0.0390 | 0.7174 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NUDT18 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUDT18:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUDT18 | 79873 | 4 | 10 | 16 | |
| GSE20123 | NUDT18 | 79873 | 4 | 10 | 16 | |
| GSE43470 | NUDT18 | 79873 | 4 | 9 | 30 | |
| GSE46452 | NUDT18 | 79873 | 13 | 13 | 33 | |
| GSE47630 | NUDT18 | 79873 | 10 | 8 | 22 | |
| GSE54993 | NUDT18 | 79873 | 2 | 14 | 54 | |
| GSE54994 | NUDT18 | 79873 | 8 | 18 | 27 | |
| GSE60625 | NUDT18 | 79873 | 3 | 0 | 8 | |
| GSE74703 | NUDT18 | 79873 | 4 | 7 | 25 | |
| GSE74704 | NUDT18 | 79873 | 3 | 7 | 10 | |
| TCGA | NUDT18 | 79873 | 13 | 43 | 40 |
Total number of gains: 68; Total number of losses: 139; Total Number of normals: 281.
Somatic mutations of NUDT18:
Generating mutation plots.
Highly correlated genes for NUDT18:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUDT18 | ANKRD16 | 0.789784 | 3 | 0 | 3 |
| NUDT18 | GRIN3B | 0.782659 | 3 | 0 | 3 |
| NUDT18 | TMEM158 | 0.733077 | 3 | 0 | 3 |
| NUDT18 | CD44 | 0.725415 | 3 | 0 | 3 |
| NUDT18 | KCTD18 | 0.708642 | 3 | 0 | 3 |
| NUDT18 | TIFAB | 0.694644 | 3 | 0 | 3 |
| NUDT18 | VASN | 0.683819 | 3 | 0 | 3 |
| NUDT18 | WIPF2 | 0.683213 | 3 | 0 | 3 |
| NUDT18 | VAPA | 0.676781 | 3 | 0 | 3 |
| NUDT18 | LAMP1 | 0.67618 | 3 | 0 | 3 |
| NUDT18 | CX3CR1 | 0.6697 | 3 | 0 | 3 |
| NUDT18 | MTA3 | 0.66299 | 3 | 0 | 3 |
| NUDT18 | MAP4K4 | 0.6556 | 4 | 0 | 3 |
| NUDT18 | SLAMF1 | 0.654928 | 4 | 0 | 3 |
| NUDT18 | CD109 | 0.654366 | 4 | 0 | 3 |
| NUDT18 | PMM2 | 0.638104 | 4 | 0 | 3 |
| NUDT18 | ARNTL2 | 0.633406 | 4 | 0 | 3 |
| NUDT18 | STRADA | 0.631627 | 4 | 0 | 3 |
| NUDT18 | ETF1 | 0.631465 | 4 | 0 | 3 |
| NUDT18 | KRT33B | 0.629675 | 4 | 0 | 3 |
For details and further investigation, click here
