| Full name: CDP-diacylglycerol--inositol 3-phosphatidyltransferase | Alias Symbol: PIS1|PIS | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 10423 | HGNC ID: HGNC:1769 | Ensembl Gene: ENSG00000103502 | OMIM ID: 605893 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CDIPT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDIPT | 10423 | 201253_s_at | -0.0363 | 0.9660 | |
| GSE20347 | CDIPT | 10423 | 201253_s_at | 0.1601 | 0.2085 | |
| GSE23400 | CDIPT | 10423 | 201253_s_at | 0.3026 | 0.0000 | |
| GSE26886 | CDIPT | 10423 | 201253_s_at | 0.4157 | 0.0264 | |
| GSE29001 | CDIPT | 10423 | 201253_s_at | 0.3509 | 0.0278 | |
| GSE38129 | CDIPT | 10423 | 201253_s_at | 0.0643 | 0.6007 | |
| GSE45670 | CDIPT | 10423 | 201253_s_at | 0.1594 | 0.1758 | |
| GSE53622 | CDIPT | 10423 | 105494 | 0.2858 | 0.0000 | |
| GSE53624 | CDIPT | 10423 | 105494 | 0.4829 | 0.0000 | |
| GSE63941 | CDIPT | 10423 | 201253_s_at | -0.9585 | 0.0072 | |
| GSE77861 | CDIPT | 10423 | 201253_s_at | 0.1089 | 0.7381 | |
| GSE97050 | CDIPT | 10423 | A_23_P501339 | 0.0985 | 0.7022 | |
| SRP007169 | CDIPT | 10423 | RNAseq | -0.4032 | 0.2928 | |
| SRP008496 | CDIPT | 10423 | RNAseq | -0.1635 | 0.4410 | |
| SRP064894 | CDIPT | 10423 | RNAseq | 0.3530 | 0.1111 | |
| SRP133303 | CDIPT | 10423 | RNAseq | 0.3153 | 0.0527 | |
| SRP159526 | CDIPT | 10423 | RNAseq | 0.4926 | 0.0128 | |
| SRP193095 | CDIPT | 10423 | RNAseq | 0.4366 | 0.0001 | |
| SRP219564 | CDIPT | 10423 | RNAseq | -0.0320 | 0.9479 | |
| TCGA | CDIPT | 10423 | RNAseq | -0.0435 | 0.3468 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDIPT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDIPT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDIPT | 10423 | 5 | 5 | 20 | |
| GSE20123 | CDIPT | 10423 | 5 | 4 | 21 | |
| GSE43470 | CDIPT | 10423 | 3 | 3 | 37 | |
| GSE46452 | CDIPT | 10423 | 38 | 1 | 20 | |
| GSE47630 | CDIPT | 10423 | 11 | 7 | 22 | |
| GSE54993 | CDIPT | 10423 | 3 | 5 | 62 | |
| GSE54994 | CDIPT | 10423 | 5 | 9 | 39 | |
| GSE60625 | CDIPT | 10423 | 4 | 0 | 7 | |
| GSE74703 | CDIPT | 10423 | 3 | 2 | 31 | |
| GSE74704 | CDIPT | 10423 | 3 | 2 | 15 | |
| TCGA | CDIPT | 10423 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of CDIPT:
Generating mutation plots.
Highly correlated genes for CDIPT:
Showing top 20/754 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDIPT | ATF1 | 0.800456 | 3 | 0 | 3 |
| CDIPT | RTF1 | 0.782733 | 3 | 0 | 3 |
| CDIPT | ATL1 | 0.764702 | 3 | 0 | 3 |
| CDIPT | NPHP3 | 0.763347 | 3 | 0 | 3 |
| CDIPT | RBM22 | 0.753677 | 3 | 0 | 3 |
| CDIPT | ZNF791 | 0.748661 | 3 | 0 | 3 |
| CDIPT | API5 | 0.747063 | 3 | 0 | 3 |
| CDIPT | KCTD18 | 0.74521 | 3 | 0 | 3 |
| CDIPT | FOXN3 | 0.739617 | 4 | 0 | 4 |
| CDIPT | DIS3L | 0.736359 | 3 | 0 | 3 |
| CDIPT | MTFMT | 0.736317 | 4 | 0 | 4 |
| CDIPT | TPRG1L | 0.736108 | 3 | 0 | 3 |
| CDIPT | ZNF578 | 0.735006 | 3 | 0 | 3 |
| CDIPT | AXL | 0.734762 | 3 | 0 | 3 |
| CDIPT | SNAP23 | 0.732818 | 3 | 0 | 3 |
| CDIPT | RAB21 | 0.730006 | 3 | 0 | 3 |
| CDIPT | ZNF626 | 0.729052 | 3 | 0 | 3 |
| CDIPT | CHAMP1 | 0.725346 | 3 | 0 | 3 |
| CDIPT | FBXO33 | 0.725335 | 3 | 0 | 3 |
| CDIPT | DPP4 | 0.719275 | 3 | 0 | 3 |
For details and further investigation, click here
