| Full name: chromosome 21 open reading frame 91 | Alias Symbol: YG81|EURL|CSSG1 | ||
| Type: protein-coding gene | Cytoband: 21q21.1 | ||
| Entrez ID: 54149 | HGNC ID: HGNC:16459 | Ensembl Gene: ENSG00000154642 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C21orf91:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C21orf91 | 54149 | 226109_at | -0.0455 | 0.9432 | |
| GSE20347 | C21orf91 | 54149 | 220941_s_at | 0.5803 | 0.0049 | |
| GSE23400 | C21orf91 | 54149 | 220941_s_at | 0.3072 | 0.0003 | |
| GSE26886 | C21orf91 | 54149 | 226109_at | -0.6402 | 0.0701 | |
| GSE29001 | C21orf91 | 54149 | 220941_s_at | 0.8274 | 0.0479 | |
| GSE38129 | C21orf91 | 54149 | 220941_s_at | 0.7927 | 0.0003 | |
| GSE45670 | C21orf91 | 54149 | 226109_at | 0.1737 | 0.5097 | |
| GSE53622 | C21orf91 | 54149 | 8974 | 0.2916 | 0.0036 | |
| GSE53624 | C21orf91 | 54149 | 8974 | 0.6948 | 0.0000 | |
| GSE63941 | C21orf91 | 54149 | 226109_at | -0.2116 | 0.8040 | |
| GSE77861 | C21orf91 | 54149 | 226109_at | 0.0561 | 0.9437 | |
| GSE97050 | C21orf91 | 54149 | A_24_P125839 | 0.3051 | 0.3136 | |
| SRP007169 | C21orf91 | 54149 | RNAseq | -0.0479 | 0.9138 | |
| SRP008496 | C21orf91 | 54149 | RNAseq | 0.5403 | 0.1185 | |
| SRP064894 | C21orf91 | 54149 | RNAseq | -0.1136 | 0.6461 | |
| SRP133303 | C21orf91 | 54149 | RNAseq | -0.2816 | 0.2257 | |
| SRP159526 | C21orf91 | 54149 | RNAseq | 0.3417 | 0.3511 | |
| SRP193095 | C21orf91 | 54149 | RNAseq | -0.0920 | 0.6064 | |
| SRP219564 | C21orf91 | 54149 | RNAseq | -0.6718 | 0.1397 | |
| TCGA | C21orf91 | 54149 | RNAseq | 0.2873 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C21orf91 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C21orf91:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C21orf91 | 54149 | 2 | 10 | 18 | |
| GSE20123 | C21orf91 | 54149 | 2 | 10 | 18 | |
| GSE43470 | C21orf91 | 54149 | 1 | 11 | 31 | |
| GSE46452 | C21orf91 | 54149 | 1 | 22 | 36 | |
| GSE47630 | C21orf91 | 54149 | 6 | 17 | 17 | |
| GSE54993 | C21orf91 | 54149 | 9 | 2 | 59 | |
| GSE54994 | C21orf91 | 54149 | 3 | 10 | 40 | |
| GSE60625 | C21orf91 | 54149 | 0 | 0 | 11 | |
| GSE74703 | C21orf91 | 54149 | 1 | 8 | 27 | |
| GSE74704 | C21orf91 | 54149 | 2 | 6 | 12 | |
| TCGA | C21orf91 | 54149 | 11 | 42 | 43 |
Total number of gains: 38; Total number of losses: 138; Total Number of normals: 312.
Somatic mutations of C21orf91:
Generating mutation plots.
Highly correlated genes for C21orf91:
Showing top 20/402 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C21orf91 | GPHN | 0.823805 | 3 | 0 | 3 |
| C21orf91 | EXOC4 | 0.813888 | 3 | 0 | 3 |
| C21orf91 | ETFA | 0.758153 | 3 | 0 | 3 |
| C21orf91 | CREBBP | 0.75309 | 4 | 0 | 4 |
| C21orf91 | ZW10 | 0.751372 | 4 | 0 | 3 |
| C21orf91 | SFT2D3 | 0.742794 | 3 | 0 | 3 |
| C21orf91 | SIKE1 | 0.740091 | 3 | 0 | 3 |
| C21orf91 | BCS1L | 0.735198 | 3 | 0 | 3 |
| C21orf91 | TET2 | 0.732045 | 3 | 0 | 3 |
| C21orf91 | MTM1 | 0.731729 | 4 | 0 | 4 |
| C21orf91 | ANKRD13C | 0.731145 | 3 | 0 | 3 |
| C21orf91 | AIFM1 | 0.730033 | 3 | 0 | 3 |
| C21orf91 | THUMPD1 | 0.729223 | 4 | 0 | 4 |
| C21orf91 | NKIRAS1 | 0.727383 | 3 | 0 | 3 |
| C21orf91 | USP38 | 0.723984 | 3 | 0 | 3 |
| C21orf91 | BORA | 0.719484 | 5 | 0 | 5 |
| C21orf91 | DCLRE1B | 0.713998 | 3 | 0 | 3 |
| C21orf91 | RRN3 | 0.711899 | 5 | 0 | 5 |
| C21orf91 | KCTD18 | 0.710795 | 4 | 0 | 4 |
| C21orf91 | SYNJ1 | 0.707416 | 3 | 0 | 3 |
For details and further investigation, click here
