| Full name: electron transfer flavoprotein dehydrogenase | Alias Symbol: ETFQO | ||
| Type: protein-coding gene | Cytoband: 4q32.1 | ||
| Entrez ID: 2110 | HGNC ID: HGNC:3483 | Ensembl Gene: ENSG00000171503 | OMIM ID: 231675 |
| Drug and gene relationship at DGIdb | |||
Expression of ETFDH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ETFDH | 2110 | 33494_at | -1.2108 | 0.1029 | |
| GSE20347 | ETFDH | 2110 | 33494_at | -1.9035 | 0.0000 | |
| GSE23400 | ETFDH | 2110 | 33494_at | -0.8440 | 0.0000 | |
| GSE26886 | ETFDH | 2110 | 205530_at | -2.5807 | 0.0000 | |
| GSE29001 | ETFDH | 2110 | 205530_at | -1.8484 | 0.0000 | |
| GSE38129 | ETFDH | 2110 | 33494_at | -1.6669 | 0.0000 | |
| GSE45670 | ETFDH | 2110 | 33494_at | -1.0875 | 0.0003 | |
| GSE53622 | ETFDH | 2110 | 8915 | -1.0862 | 0.0000 | |
| GSE53624 | ETFDH | 2110 | 8915 | -0.9181 | 0.0000 | |
| GSE63941 | ETFDH | 2110 | 33494_at | -0.9700 | 0.1061 | |
| GSE77861 | ETFDH | 2110 | 205530_at | -1.6970 | 0.0007 | |
| GSE97050 | ETFDH | 2110 | A_23_P61447 | -0.2127 | 0.5982 | |
| SRP007169 | ETFDH | 2110 | RNAseq | -1.6709 | 0.0011 | |
| SRP008496 | ETFDH | 2110 | RNAseq | -1.5406 | 0.0000 | |
| SRP064894 | ETFDH | 2110 | RNAseq | -1.7338 | 0.0000 | |
| SRP133303 | ETFDH | 2110 | RNAseq | -1.0607 | 0.0000 | |
| SRP159526 | ETFDH | 2110 | RNAseq | -1.3546 | 0.0000 | |
| SRP193095 | ETFDH | 2110 | RNAseq | -1.6207 | 0.0000 | |
| SRP219564 | ETFDH | 2110 | RNAseq | -1.8372 | 0.0000 | |
| TCGA | ETFDH | 2110 | RNAseq | -0.5380 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by ETFDH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ETFDH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ETFDH | 2110 | 0 | 13 | 17 | |
| GSE20123 | ETFDH | 2110 | 0 | 13 | 17 | |
| GSE43470 | ETFDH | 2110 | 0 | 14 | 29 | |
| GSE46452 | ETFDH | 2110 | 1 | 36 | 22 | |
| GSE47630 | ETFDH | 2110 | 0 | 23 | 17 | |
| GSE54993 | ETFDH | 2110 | 10 | 0 | 60 | |
| GSE54994 | ETFDH | 2110 | 1 | 12 | 40 | |
| GSE60625 | ETFDH | 2110 | 0 | 1 | 10 | |
| GSE74703 | ETFDH | 2110 | 0 | 12 | 24 | |
| GSE74704 | ETFDH | 2110 | 0 | 6 | 14 | |
| TCGA | ETFDH | 2110 | 12 | 35 | 49 |
Total number of gains: 24; Total number of losses: 165; Total Number of normals: 299.
Somatic mutations of ETFDH:
Generating mutation plots.
Highly correlated genes for ETFDH:
Showing top 20/1518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ETFDH | UBL3 | 0.874837 | 10 | 0 | 10 |
| ETFDH | HPGD | 0.866439 | 10 | 0 | 10 |
| ETFDH | KRT78 | 0.856452 | 6 | 0 | 6 |
| ETFDH | SFTA2 | 0.85373 | 4 | 0 | 4 |
| ETFDH | RMND5B | 0.848658 | 10 | 0 | 10 |
| ETFDH | CRISP3 | 0.842752 | 10 | 0 | 10 |
| ETFDH | SNORA68 | 0.842243 | 4 | 0 | 4 |
| ETFDH | FAM3D | 0.833148 | 6 | 0 | 6 |
| ETFDH | GYS2 | 0.830032 | 10 | 0 | 10 |
| ETFDH | GDPD3 | 0.829916 | 10 | 0 | 10 |
| ETFDH | NUCB2 | 0.826784 | 11 | 0 | 11 |
| ETFDH | SLC16A6 | 0.820528 | 10 | 0 | 10 |
| ETFDH | SMIM5 | 0.820126 | 6 | 0 | 6 |
| ETFDH | CAST | 0.820041 | 10 | 0 | 10 |
| ETFDH | ABLIM3 | 0.819341 | 10 | 0 | 10 |
| ETFDH | GPD1L | 0.816458 | 10 | 0 | 10 |
| ETFDH | SORT1 | 0.81211 | 10 | 0 | 10 |
| ETFDH | MAL | 0.811514 | 10 | 0 | 10 |
| ETFDH | CXCR2 | 0.809523 | 11 | 0 | 11 |
| ETFDH | TP53I3 | 0.809258 | 10 | 0 | 10 |
For details and further investigation, click here
