| Full name: kinesin family member 2A | Alias Symbol: HK2 | ||
| Type: protein-coding gene | Cytoband: 5q12.1 | ||
| Entrez ID: 3796 | HGNC ID: HGNC:6318 | Ensembl Gene: ENSG00000068796 | OMIM ID: 602591 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KIF2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIF2A | 3796 | 203087_s_at | 0.4219 | 0.4299 | |
| GSE20347 | KIF2A | 3796 | 203087_s_at | 0.3546 | 0.1174 | |
| GSE23400 | KIF2A | 3796 | 203087_s_at | 0.6353 | 0.0000 | |
| GSE26886 | KIF2A | 3796 | 203087_s_at | -0.0652 | 0.8113 | |
| GSE29001 | KIF2A | 3796 | 203087_s_at | 0.4049 | 0.2450 | |
| GSE38129 | KIF2A | 3796 | 203087_s_at | 0.7216 | 0.0000 | |
| GSE45670 | KIF2A | 3796 | 203087_s_at | 0.5887 | 0.0008 | |
| GSE53622 | KIF2A | 3796 | 104908 | 0.0300 | 0.7110 | |
| GSE53624 | KIF2A | 3796 | 104908 | 0.3823 | 0.0000 | |
| GSE63941 | KIF2A | 3796 | 203087_s_at | 0.4673 | 0.3512 | |
| GSE77861 | KIF2A | 3796 | 203087_s_at | 0.1146 | 0.7433 | |
| GSE97050 | KIF2A | 3796 | A_33_P3407065 | 0.1777 | 0.5249 | |
| SRP007169 | KIF2A | 3796 | RNAseq | 0.2816 | 0.3765 | |
| SRP008496 | KIF2A | 3796 | RNAseq | 0.2518 | 0.1866 | |
| SRP064894 | KIF2A | 3796 | RNAseq | -0.0748 | 0.7169 | |
| SRP133303 | KIF2A | 3796 | RNAseq | 0.3709 | 0.0110 | |
| SRP159526 | KIF2A | 3796 | RNAseq | 0.1483 | 0.6359 | |
| SRP193095 | KIF2A | 3796 | RNAseq | -0.0754 | 0.3766 | |
| SRP219564 | KIF2A | 3796 | RNAseq | -0.3330 | 0.4199 | |
| TCGA | KIF2A | 3796 | RNAseq | 0.1327 | 0.0231 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIF2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIF2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIF2A | 3796 | 0 | 13 | 17 | |
| GSE20123 | KIF2A | 3796 | 0 | 13 | 17 | |
| GSE43470 | KIF2A | 3796 | 1 | 12 | 30 | |
| GSE46452 | KIF2A | 3796 | 0 | 28 | 31 | |
| GSE47630 | KIF2A | 3796 | 2 | 17 | 21 | |
| GSE54993 | KIF2A | 3796 | 8 | 1 | 61 | |
| GSE54994 | KIF2A | 3796 | 1 | 19 | 33 | |
| GSE60625 | KIF2A | 3796 | 0 | 0 | 11 | |
| GSE74703 | KIF2A | 3796 | 1 | 9 | 26 | |
| GSE74704 | KIF2A | 3796 | 0 | 6 | 14 | |
| TCGA | KIF2A | 3796 | 5 | 50 | 41 |
Total number of gains: 18; Total number of losses: 168; Total Number of normals: 302.
Somatic mutations of KIF2A:
Generating mutation plots.
Highly correlated genes for KIF2A:
Showing top 20/944 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIF2A | TRMT6 | 0.793544 | 3 | 0 | 3 |
| KIF2A | SAAL1 | 0.787838 | 3 | 0 | 3 |
| KIF2A | CLEC4A | 0.761098 | 3 | 0 | 3 |
| KIF2A | AGTRAP | 0.759249 | 3 | 0 | 3 |
| KIF2A | LYAR | 0.753775 | 3 | 0 | 3 |
| KIF2A | MAD2L2 | 0.74084 | 3 | 0 | 3 |
| KIF2A | NUS1 | 0.728315 | 3 | 0 | 3 |
| KIF2A | CSNK2A2 | 0.725589 | 3 | 0 | 3 |
| KIF2A | CPT1C | 0.717874 | 3 | 0 | 3 |
| KIF2A | TMEM167A | 0.717443 | 5 | 0 | 5 |
| KIF2A | RLIM | 0.714745 | 3 | 0 | 3 |
| KIF2A | JKAMP | 0.713008 | 4 | 0 | 4 |
| KIF2A | SLC7A6OS | 0.707649 | 3 | 0 | 3 |
| KIF2A | SEC23A | 0.703321 | 3 | 0 | 3 |
| KIF2A | VPS35 | 0.694562 | 4 | 0 | 3 |
| KIF2A | CCDC102B | 0.693278 | 4 | 0 | 4 |
| KIF2A | CXCL16 | 0.692568 | 3 | 0 | 3 |
| KIF2A | MRPL10 | 0.691664 | 3 | 0 | 3 |
| KIF2A | DNAJA1 | 0.685122 | 8 | 0 | 7 |
| KIF2A | SLC41A1 | 0.684354 | 3 | 0 | 3 |
For details and further investigation, click here
