| Full name: Ly1 antibody reactive | Alias Symbol: ZC2HC2|ZLYAR | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 55646 | HGNC ID: HGNC:26021 | Ensembl Gene: ENSG00000145220 | OMIM ID: 617684 |
| Drug and gene relationship at DGIdb | |||
Expression of LYAR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYAR | 55646 | 223413_s_at | 0.9513 | 0.2679 | |
| GSE26886 | LYAR | 55646 | 223413_s_at | 0.5346 | 0.0900 | |
| GSE45670 | LYAR | 55646 | 223413_s_at | 0.5202 | 0.0107 | |
| GSE53622 | LYAR | 55646 | 94367 | 0.5604 | 0.0000 | |
| GSE53624 | LYAR | 55646 | 94367 | 0.7901 | 0.0000 | |
| GSE63941 | LYAR | 55646 | 223413_s_at | 0.3360 | 0.6356 | |
| GSE77861 | LYAR | 55646 | 223414_s_at | 0.5456 | 0.1012 | |
| GSE97050 | LYAR | 55646 | A_23_P41327 | 0.3214 | 0.2501 | |
| SRP007169 | LYAR | 55646 | RNAseq | 1.8155 | 0.0499 | |
| SRP064894 | LYAR | 55646 | RNAseq | 0.5268 | 0.0347 | |
| SRP133303 | LYAR | 55646 | RNAseq | 0.6098 | 0.0011 | |
| SRP159526 | LYAR | 55646 | RNAseq | 0.3315 | 0.3689 | |
| SRP193095 | LYAR | 55646 | RNAseq | 0.2621 | 0.0900 | |
| SRP219564 | LYAR | 55646 | RNAseq | 0.4899 | 0.2355 | |
| TCGA | LYAR | 55646 | RNAseq | 0.3501 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LYAR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYAR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYAR | 55646 | 0 | 17 | 13 | |
| GSE20123 | LYAR | 55646 | 0 | 17 | 13 | |
| GSE43470 | LYAR | 55646 | 0 | 17 | 26 | |
| GSE46452 | LYAR | 55646 | 1 | 36 | 22 | |
| GSE47630 | LYAR | 55646 | 1 | 19 | 20 | |
| GSE54993 | LYAR | 55646 | 10 | 0 | 60 | |
| GSE54994 | LYAR | 55646 | 3 | 12 | 38 | |
| GSE60625 | LYAR | 55646 | 0 | 0 | 11 | |
| GSE74703 | LYAR | 55646 | 0 | 13 | 23 | |
| GSE74704 | LYAR | 55646 | 0 | 9 | 11 | |
| TCGA | LYAR | 55646 | 7 | 47 | 42 |
Total number of gains: 22; Total number of losses: 187; Total Number of normals: 279.
Somatic mutations of LYAR:
Generating mutation plots.
Highly correlated genes for LYAR:
Showing top 20/1278 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYAR | FANCL | 0.834657 | 3 | 0 | 3 |
| LYAR | ZBED6 | 0.815664 | 3 | 0 | 3 |
| LYAR | SLC25A16 | 0.805081 | 3 | 0 | 3 |
| LYAR | CHD7 | 0.803588 | 3 | 0 | 3 |
| LYAR | CHD8 | 0.797285 | 3 | 0 | 3 |
| LYAR | ZNF584 | 0.796745 | 3 | 0 | 3 |
| LYAR | BCL9L | 0.778989 | 3 | 0 | 3 |
| LYAR | CXCL5 | 0.778426 | 3 | 0 | 3 |
| LYAR | GPATCH2 | 0.776061 | 3 | 0 | 3 |
| LYAR | ICAM1 | 0.771794 | 3 | 0 | 3 |
| LYAR | RPF2 | 0.767565 | 8 | 0 | 8 |
| LYAR | RRM2B | 0.764253 | 3 | 0 | 3 |
| LYAR | MTPAP | 0.757613 | 3 | 0 | 3 |
| LYAR | FAM86C1 | 0.757056 | 3 | 0 | 3 |
| LYAR | STX16 | 0.756611 | 4 | 0 | 3 |
| LYAR | STRN3 | 0.753846 | 3 | 0 | 3 |
| LYAR | KIF2A | 0.753775 | 3 | 0 | 3 |
| LYAR | TBRG4 | 0.752661 | 3 | 0 | 3 |
| LYAR | PPP1R37 | 0.749137 | 3 | 0 | 3 |
| LYAR | CPT1A | 0.739934 | 3 | 0 | 3 |
For details and further investigation, click here
