| Full name: angiotensin II receptor associated protein | Alias Symbol: ATRAP | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 57085 | HGNC ID: HGNC:13539 | Ensembl Gene: ENSG00000177674 | OMIM ID: 608729 |
| Drug and gene relationship at DGIdb | |||
Expression of AGTRAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGTRAP | 57085 | 225059_at | 0.9347 | 0.0249 | |
| GSE26886 | AGTRAP | 57085 | 225059_at | 0.6005 | 0.0394 | |
| GSE45670 | AGTRAP | 57085 | 225059_at | 1.0012 | 0.0001 | |
| GSE63941 | AGTRAP | 57085 | 1555736_a_at | 1.3102 | 0.0406 | |
| GSE77861 | AGTRAP | 57085 | 225059_at | 0.2468 | 0.3895 | |
| GSE97050 | AGTRAP | 57085 | A_23_P158596 | -0.0844 | 0.8689 | |
| SRP007169 | AGTRAP | 57085 | RNAseq | -0.1227 | 0.7989 | |
| SRP008496 | AGTRAP | 57085 | RNAseq | -0.3187 | 0.3425 | |
| SRP064894 | AGTRAP | 57085 | RNAseq | 1.5974 | 0.0000 | |
| SRP133303 | AGTRAP | 57085 | RNAseq | 1.0633 | 0.0007 | |
| SRP159526 | AGTRAP | 57085 | RNAseq | 0.6949 | 0.0593 | |
| SRP193095 | AGTRAP | 57085 | RNAseq | 1.1672 | 0.0000 | |
| SRP219564 | AGTRAP | 57085 | RNAseq | 0.9569 | 0.0748 | |
| TCGA | AGTRAP | 57085 | RNAseq | 0.4912 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by AGTRAP expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of AGTRAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGTRAP | 57085 | 0 | 5 | 25 | |
| GSE20123 | AGTRAP | 57085 | 0 | 4 | 26 | |
| GSE43470 | AGTRAP | 57085 | 4 | 6 | 33 | |
| GSE46452 | AGTRAP | 57085 | 7 | 1 | 51 | |
| GSE47630 | AGTRAP | 57085 | 8 | 4 | 28 | |
| GSE54993 | AGTRAP | 57085 | 3 | 1 | 66 | |
| GSE54994 | AGTRAP | 57085 | 11 | 4 | 38 | |
| GSE60625 | AGTRAP | 57085 | 0 | 0 | 11 | |
| GSE74703 | AGTRAP | 57085 | 3 | 4 | 29 | |
| GSE74704 | AGTRAP | 57085 | 0 | 0 | 20 | |
| TCGA | AGTRAP | 57085 | 10 | 23 | 63 |
Total number of gains: 46; Total number of losses: 52; Total Number of normals: 390.
Somatic mutations of AGTRAP:
Generating mutation plots.
Highly correlated genes for AGTRAP:
Showing top 20/1010 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGTRAP | ABCE1 | 0.797114 | 3 | 0 | 3 |
| AGTRAP | CCT6A | 0.774764 | 3 | 0 | 3 |
| AGTRAP | CENPE | 0.763893 | 3 | 0 | 3 |
| AGTRAP | INTS1 | 0.761363 | 4 | 0 | 4 |
| AGTRAP | RPS6KA1 | 0.760269 | 5 | 0 | 5 |
| AGTRAP | KIF2A | 0.759249 | 3 | 0 | 3 |
| AGTRAP | ATP6V1C1 | 0.751362 | 3 | 0 | 3 |
| AGTRAP | SRRD | 0.749241 | 3 | 0 | 3 |
| AGTRAP | LILRB2 | 0.748601 | 3 | 0 | 3 |
| AGTRAP | NUDCD1 | 0.742249 | 3 | 0 | 3 |
| AGTRAP | ASXL1 | 0.741626 | 3 | 0 | 3 |
| AGTRAP | OASL | 0.740636 | 3 | 0 | 3 |
| AGTRAP | CTSB | 0.739966 | 4 | 0 | 4 |
| AGTRAP | LINGO1 | 0.734004 | 3 | 0 | 3 |
| AGTRAP | TAP1 | 0.730224 | 4 | 0 | 4 |
| AGTRAP | CENPQ | 0.728738 | 3 | 0 | 3 |
| AGTRAP | CHST11 | 0.727356 | 5 | 0 | 5 |
| AGTRAP | NAT10 | 0.727061 | 3 | 0 | 3 |
| AGTRAP | FANCE | 0.726821 | 3 | 0 | 3 |
| AGTRAP | NDUFB4 | 0.725711 | 3 | 0 | 3 |
For details and further investigation, click here
