| Full name: C-type lectin domain family 4 member A | Alias Symbol: DCIR|DDB27|CD367 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 50856 | HGNC ID: HGNC:13257 | Ensembl Gene: ENSG00000111729 | OMIM ID: 605306 |
| Drug and gene relationship at DGIdb | |||
Expression of CLEC4A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLEC4A | 50856 | 221724_s_at | 0.4026 | 0.5458 | |
| GSE20347 | CLEC4A | 50856 | 221724_s_at | -0.0431 | 0.5394 | |
| GSE23400 | CLEC4A | 50856 | 221724_s_at | -0.0017 | 0.9677 | |
| GSE26886 | CLEC4A | 50856 | 219947_at | -0.7466 | 0.0796 | |
| GSE29001 | CLEC4A | 50856 | 219947_at | 0.4220 | 0.2711 | |
| GSE38129 | CLEC4A | 50856 | 221724_s_at | 0.0192 | 0.8836 | |
| GSE45670 | CLEC4A | 50856 | 219947_at | -0.0915 | 0.8170 | |
| GSE53622 | CLEC4A | 50856 | 17838 | 0.6840 | 0.0000 | |
| GSE53624 | CLEC4A | 50856 | 17838 | 0.4595 | 0.0216 | |
| GSE63941 | CLEC4A | 50856 | 221724_s_at | -0.0522 | 0.7191 | |
| GSE77861 | CLEC4A | 50856 | 221724_s_at | -0.0487 | 0.6268 | |
| GSE97050 | CLEC4A | 50856 | A_23_P48029 | 0.4480 | 0.2084 | |
| SRP007169 | CLEC4A | 50856 | RNAseq | 1.7354 | 0.0415 | |
| SRP064894 | CLEC4A | 50856 | RNAseq | 1.2397 | 0.0000 | |
| SRP133303 | CLEC4A | 50856 | RNAseq | 1.0442 | 0.0001 | |
| SRP159526 | CLEC4A | 50856 | RNAseq | 0.2293 | 0.6675 | |
| SRP193095 | CLEC4A | 50856 | RNAseq | 0.8885 | 0.0001 | |
| SRP219564 | CLEC4A | 50856 | RNAseq | 0.7882 | 0.0335 | |
| TCGA | CLEC4A | 50856 | RNAseq | 0.7331 | 0.0007 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CLEC4A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLEC4A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLEC4A | 50856 | 6 | 3 | 21 | |
| GSE20123 | CLEC4A | 50856 | 6 | 3 | 21 | |
| GSE43470 | CLEC4A | 50856 | 7 | 3 | 33 | |
| GSE46452 | CLEC4A | 50856 | 10 | 1 | 48 | |
| GSE47630 | CLEC4A | 50856 | 12 | 2 | 26 | |
| GSE54993 | CLEC4A | 50856 | 1 | 10 | 59 | |
| GSE54994 | CLEC4A | 50856 | 9 | 3 | 41 | |
| GSE60625 | CLEC4A | 50856 | 0 | 1 | 10 | |
| GSE74703 | CLEC4A | 50856 | 7 | 2 | 27 | |
| GSE74704 | CLEC4A | 50856 | 4 | 2 | 14 | |
| TCGA | CLEC4A | 50856 | 40 | 6 | 50 |
Total number of gains: 102; Total number of losses: 36; Total Number of normals: 350.
Somatic mutations of CLEC4A:
Generating mutation plots.
Highly correlated genes for CLEC4A:
Showing top 20/417 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLEC4A | GPR141 | 0.830832 | 3 | 0 | 3 |
| CLEC4A | FCGR3A | 0.778504 | 3 | 0 | 3 |
| CLEC4A | KIF2A | 0.761098 | 3 | 0 | 3 |
| CLEC4A | ZNF90 | 0.76 | 3 | 0 | 3 |
| CLEC4A | PLEK | 0.722838 | 5 | 0 | 5 |
| CLEC4A | CCRL2 | 0.715852 | 8 | 0 | 7 |
| CLEC4A | RGS18 | 0.714134 | 7 | 0 | 7 |
| CLEC4A | C19orf38 | 0.70663 | 3 | 0 | 3 |
| CLEC4A | ARHGAP15 | 0.706226 | 3 | 0 | 3 |
| CLEC4A | CDC123 | 0.703441 | 3 | 0 | 3 |
| CLEC4A | DPP4 | 0.702944 | 4 | 0 | 4 |
| CLEC4A | MEX3B | 0.702035 | 4 | 0 | 4 |
| CLEC4A | SNX20 | 0.699241 | 6 | 0 | 6 |
| CLEC4A | CLEC12A | 0.696271 | 4 | 0 | 4 |
| CLEC4A | IL2RA | 0.694478 | 5 | 0 | 4 |
| CLEC4A | ZNF267 | 0.694424 | 3 | 0 | 3 |
| CLEC4A | LTF | 0.691455 | 3 | 0 | 3 |
| CLEC4A | RAB42 | 0.687778 | 3 | 0 | 3 |
| CLEC4A | CYBB | 0.687634 | 10 | 0 | 10 |
| CLEC4A | NAGLU | 0.686551 | 3 | 0 | 3 |
For details and further investigation, click here
