| Full name: DnaJ heat shock protein family (Hsp40) member A1 | Alias Symbol: HSPF4|hdj-2|dj-2|NEDD7 | ||
| Type: protein-coding gene | Cytoband: 9p21.1 | ||
| Entrez ID: 3301 | HGNC ID: HGNC:5229 | Ensembl Gene: ENSG00000086061 | OMIM ID: 602837 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DNAJA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJA1 | 3301 | 200881_s_at | 0.0774 | 0.9256 | |
| GSE20347 | DNAJA1 | 3301 | 200881_s_at | 0.6446 | 0.0062 | |
| GSE23400 | DNAJA1 | 3301 | 200881_s_at | 0.8854 | 0.0000 | |
| GSE26886 | DNAJA1 | 3301 | 200881_s_at | 0.1707 | 0.4564 | |
| GSE29001 | DNAJA1 | 3301 | 200880_at | 0.8256 | 0.0311 | |
| GSE38129 | DNAJA1 | 3301 | 200881_s_at | 0.7320 | 0.0001 | |
| GSE45670 | DNAJA1 | 3301 | 200881_s_at | 0.8611 | 0.0025 | |
| GSE53622 | DNAJA1 | 3301 | 136956 | 0.7126 | 0.0000 | |
| GSE53624 | DNAJA1 | 3301 | 136956 | 0.8438 | 0.0000 | |
| GSE63941 | DNAJA1 | 3301 | 200881_s_at | 0.0677 | 0.8904 | |
| GSE77861 | DNAJA1 | 3301 | 200881_s_at | 0.4445 | 0.3980 | |
| GSE97050 | DNAJA1 | 3301 | A_24_P9671 | 0.1056 | 0.6195 | |
| SRP007169 | DNAJA1 | 3301 | RNAseq | 1.1787 | 0.0842 | |
| SRP008496 | DNAJA1 | 3301 | RNAseq | 1.1161 | 0.0080 | |
| SRP064894 | DNAJA1 | 3301 | RNAseq | 0.8258 | 0.0000 | |
| SRP133303 | DNAJA1 | 3301 | RNAseq | 0.7403 | 0.0000 | |
| SRP159526 | DNAJA1 | 3301 | RNAseq | 0.4369 | 0.3172 | |
| SRP193095 | DNAJA1 | 3301 | RNAseq | 0.2189 | 0.1491 | |
| SRP219564 | DNAJA1 | 3301 | RNAseq | 0.2372 | 0.7228 | |
| TCGA | DNAJA1 | 3301 | RNAseq | 0.0210 | 0.6948 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DNAJA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJA1 | 3301 | 3 | 14 | 13 | |
| GSE20123 | DNAJA1 | 3301 | 3 | 14 | 13 | |
| GSE43470 | DNAJA1 | 3301 | 4 | 10 | 29 | |
| GSE46452 | DNAJA1 | 3301 | 7 | 15 | 37 | |
| GSE47630 | DNAJA1 | 3301 | 1 | 21 | 18 | |
| GSE54993 | DNAJA1 | 3301 | 6 | 0 | 64 | |
| GSE54994 | DNAJA1 | 3301 | 7 | 11 | 35 | |
| GSE60625 | DNAJA1 | 3301 | 0 | 0 | 11 | |
| GSE74703 | DNAJA1 | 3301 | 3 | 7 | 26 | |
| GSE74704 | DNAJA1 | 3301 | 0 | 11 | 9 | |
| TCGA | DNAJA1 | 3301 | 16 | 44 | 36 |
Total number of gains: 50; Total number of losses: 147; Total Number of normals: 291.
Somatic mutations of DNAJA1:
Generating mutation plots.
Highly correlated genes for DNAJA1:
Showing top 20/1086 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJA1 | FAM160B1 | 0.78067 | 3 | 0 | 3 |
| DNAJA1 | CHMP5 | 0.74461 | 4 | 0 | 4 |
| DNAJA1 | RAB34 | 0.737981 | 3 | 0 | 3 |
| DNAJA1 | BSDC1 | 0.728512 | 3 | 0 | 3 |
| DNAJA1 | HSPH1 | 0.698099 | 9 | 0 | 8 |
| DNAJA1 | RAB23 | 0.697581 | 3 | 0 | 3 |
| DNAJA1 | HSPA8 | 0.696901 | 3 | 0 | 3 |
| DNAJA1 | CEP170 | 0.693854 | 3 | 0 | 3 |
| DNAJA1 | WDR54 | 0.687148 | 4 | 0 | 4 |
| DNAJA1 | MAD2L2 | 0.687111 | 4 | 0 | 4 |
| DNAJA1 | GNG10 | 0.686382 | 3 | 0 | 3 |
| DNAJA1 | KIF2A | 0.685122 | 8 | 0 | 7 |
| DNAJA1 | SPEN | 0.683317 | 3 | 0 | 3 |
| DNAJA1 | GLS | 0.68326 | 4 | 0 | 3 |
| DNAJA1 | CRHBP | 0.68279 | 3 | 0 | 3 |
| DNAJA1 | FADS1 | 0.681379 | 3 | 0 | 3 |
| DNAJA1 | NUDCD1 | 0.680303 | 4 | 0 | 4 |
| DNAJA1 | PCMT1 | 0.678172 | 4 | 0 | 3 |
| DNAJA1 | ELOF1 | 0.675406 | 3 | 0 | 3 |
| DNAJA1 | FXR1 | 0.674231 | 6 | 0 | 6 |
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