| Full name: Ras like without CAAX 2 | Alias Symbol: RIBA | ||
| Type: protein-coding gene | Cytoband: 18q12.3 | ||
| Entrez ID: 6014 | HGNC ID: HGNC:10017 | Ensembl Gene: ENSG00000152214 | OMIM ID: 609592 |
| Drug and gene relationship at DGIdb | |||
Expression of RIT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIT2 | 6014 | 206984_s_at | 0.1220 | 0.5623 | |
| GSE20347 | RIT2 | 6014 | 206984_s_at | -0.0074 | 0.8959 | |
| GSE23400 | RIT2 | 6014 | 206984_s_at | -0.1310 | 0.0001 | |
| GSE26886 | RIT2 | 6014 | 206984_s_at | -0.0314 | 0.7523 | |
| GSE29001 | RIT2 | 6014 | 206984_s_at | -0.1472 | 0.3490 | |
| GSE38129 | RIT2 | 6014 | 206984_s_at | -0.0586 | 0.2585 | |
| GSE45670 | RIT2 | 6014 | 206984_s_at | -0.0212 | 0.8159 | |
| GSE53622 | RIT2 | 6014 | 8294 | 0.0937 | 0.1259 | |
| GSE53624 | RIT2 | 6014 | 8294 | 0.2767 | 0.0069 | |
| GSE63941 | RIT2 | 6014 | 206984_s_at | 0.1841 | 0.6987 | |
| GSE77861 | RIT2 | 6014 | 206984_s_at | -0.1041 | 0.2952 | |
| GSE97050 | RIT2 | 6014 | A_33_P3416588 | 0.3613 | 0.3130 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RIT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIT2 | 6014 | 1 | 6 | 23 | |
| GSE20123 | RIT2 | 6014 | 1 | 6 | 23 | |
| GSE43470 | RIT2 | 6014 | 0 | 4 | 39 | |
| GSE46452 | RIT2 | 6014 | 1 | 25 | 33 | |
| GSE47630 | RIT2 | 6014 | 5 | 20 | 15 | |
| GSE54993 | RIT2 | 6014 | 8 | 1 | 61 | |
| GSE54994 | RIT2 | 6014 | 2 | 15 | 36 | |
| GSE60625 | RIT2 | 6014 | 0 | 4 | 7 | |
| GSE74703 | RIT2 | 6014 | 0 | 3 | 33 | |
| GSE74704 | RIT2 | 6014 | 0 | 4 | 16 | |
| TCGA | RIT2 | 6014 | 14 | 39 | 43 |
Total number of gains: 32; Total number of losses: 127; Total Number of normals: 329.
Somatic mutations of RIT2:
Generating mutation plots.
Highly correlated genes for RIT2:
Showing top 20/531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIT2 | ASMT | 0.768979 | 3 | 0 | 3 |
| RIT2 | VPS53 | 0.763181 | 3 | 0 | 3 |
| RIT2 | GPR153 | 0.761995 | 3 | 0 | 3 |
| RIT2 | A1BG | 0.748915 | 3 | 0 | 3 |
| RIT2 | SLC43A2 | 0.744498 | 3 | 0 | 3 |
| RIT2 | KCNQ3 | 0.736308 | 3 | 0 | 3 |
| RIT2 | KLF16 | 0.732052 | 3 | 0 | 3 |
| RIT2 | SULT2A1 | 0.723677 | 3 | 0 | 3 |
| RIT2 | RNF165 | 0.720926 | 3 | 0 | 3 |
| RIT2 | RABEP2 | 0.713249 | 4 | 0 | 4 |
| RIT2 | UBASH3A | 0.712704 | 4 | 0 | 4 |
| RIT2 | GRIN2D | 0.709275 | 3 | 0 | 3 |
| RIT2 | KRT81 | 0.708737 | 3 | 0 | 3 |
| RIT2 | ACRBP | 0.708593 | 3 | 0 | 3 |
| RIT2 | HDAC11 | 0.708508 | 4 | 0 | 4 |
| RIT2 | CD80 | 0.708132 | 5 | 0 | 4 |
| RIT2 | SLCO5A1 | 0.708026 | 3 | 0 | 3 |
| RIT2 | MROH2A | 0.707687 | 3 | 0 | 3 |
| RIT2 | ARFRP1 | 0.704222 | 3 | 0 | 3 |
| RIT2 | RORB | 0.704168 | 3 | 0 | 3 |
For details and further investigation, click here
