| Full name: keratin 81 | Alias Symbol: Hb-1 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3887 | HGNC ID: HGNC:6458 | Ensembl Gene: ENSG00000205426 | OMIM ID: 602153 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT81:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT81 | 3887 | 213711_at | -0.0610 | 0.8755 | |
| GSE20347 | KRT81 | 3887 | 213711_at | -0.0329 | 0.7099 | |
| GSE23400 | KRT81 | 3887 | 213711_at | -0.1974 | 0.0000 | |
| GSE26886 | KRT81 | 3887 | 213711_at | 0.4254 | 0.0039 | |
| GSE29001 | KRT81 | 3887 | 213711_at | 0.1604 | 0.6593 | |
| GSE38129 | KRT81 | 3887 | 213711_at | -0.1310 | 0.1022 | |
| GSE45670 | KRT81 | 3887 | 213711_at | 0.1967 | 0.1230 | |
| GSE53622 | KRT81 | 3887 | 23738 | -0.3551 | 0.0005 | |
| GSE53624 | KRT81 | 3887 | 23738 | -0.2336 | 0.0254 | |
| GSE63941 | KRT81 | 3887 | 213711_at | 0.9137 | 0.3566 | |
| GSE77861 | KRT81 | 3887 | 213711_at | 0.0264 | 0.8433 | |
| GSE97050 | KRT81 | 3887 | A_33_P3273534 | -0.3036 | 0.4197 | |
| TCGA | KRT81 | 3887 | RNAseq | 1.7796 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KRT81 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT81:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT81 | 3887 | 8 | 1 | 21 | |
| GSE20123 | KRT81 | 3887 | 8 | 1 | 21 | |
| GSE43470 | KRT81 | 3887 | 3 | 0 | 40 | |
| GSE46452 | KRT81 | 3887 | 7 | 1 | 51 | |
| GSE47630 | KRT81 | 3887 | 10 | 2 | 28 | |
| GSE54993 | KRT81 | 3887 | 0 | 5 | 65 | |
| GSE54994 | KRT81 | 3887 | 3 | 2 | 48 | |
| GSE60625 | KRT81 | 3887 | 0 | 0 | 11 | |
| GSE74703 | KRT81 | 3887 | 3 | 0 | 33 | |
| GSE74704 | KRT81 | 3887 | 5 | 1 | 14 | |
| TCGA | KRT81 | 3887 | 12 | 11 | 73 |
Total number of gains: 59; Total number of losses: 24; Total Number of normals: 405.
Somatic mutations of KRT81:
Generating mutation plots.
Highly correlated genes for KRT81:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT81 | SLC35F1 | 0.766692 | 3 | 0 | 3 |
| KRT81 | CABIN1 | 0.753744 | 4 | 0 | 4 |
| KRT81 | NR4A1 | 0.74397 | 4 | 0 | 3 |
| KRT81 | UBXN10 | 0.733763 | 4 | 0 | 4 |
| KRT81 | NFAM1 | 0.725753 | 3 | 0 | 3 |
| KRT81 | SFTPA2 | 0.722432 | 3 | 0 | 3 |
| KRT81 | RBKS | 0.721496 | 3 | 0 | 3 |
| KRT81 | KLF16 | 0.720934 | 4 | 0 | 4 |
| KRT81 | PCGF2 | 0.710797 | 4 | 0 | 4 |
| KRT81 | IDS | 0.708985 | 3 | 0 | 3 |
| KRT81 | RIT2 | 0.708737 | 3 | 0 | 3 |
| KRT81 | OBP2A | 0.696699 | 3 | 0 | 3 |
| KRT81 | DNAJC18 | 0.692957 | 3 | 0 | 3 |
| KRT81 | SGCA | 0.692147 | 4 | 0 | 3 |
| KRT81 | ICAM5 | 0.691609 | 4 | 0 | 3 |
| KRT81 | FHOD3 | 0.689827 | 3 | 0 | 3 |
| KRT81 | KRTAP21-2 | 0.688869 | 3 | 0 | 3 |
| KRT81 | FIBCD1 | 0.687361 | 5 | 0 | 4 |
| KRT81 | ASB16 | 0.687263 | 3 | 0 | 3 |
| KRT81 | PI16 | 0.686019 | 4 | 0 | 3 |
For details and further investigation, click here
