| Full name: kelch domain containing 9 | Alias Symbol: KARCA1 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 126823 | HGNC ID: HGNC:28489 | Ensembl Gene: ENSG00000162755 | OMIM ID: 617375 |
| Drug and gene relationship at DGIdb | |||
Expression of KLHDC9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHDC9 | 126823 | 227582_at | -0.6579 | 0.3490 | |
| GSE26886 | KLHDC9 | 126823 | 227582_at | 0.1963 | 0.4416 | |
| GSE45670 | KLHDC9 | 126823 | 227582_at | -0.1957 | 0.3735 | |
| GSE53622 | KLHDC9 | 126823 | 78122 | -0.7761 | 0.0000 | |
| GSE53624 | KLHDC9 | 126823 | 78122 | -0.5373 | 0.0001 | |
| GSE63941 | KLHDC9 | 126823 | 227582_at | 0.5131 | 0.5917 | |
| GSE77861 | KLHDC9 | 126823 | 227582_at | -0.0360 | 0.8859 | |
| GSE97050 | KLHDC9 | 126823 | A_23_P86100 | -0.0212 | 0.9699 | |
| SRP064894 | KLHDC9 | 126823 | RNAseq | -0.9388 | 0.0386 | |
| SRP133303 | KLHDC9 | 126823 | RNAseq | -0.6468 | 0.0276 | |
| SRP159526 | KLHDC9 | 126823 | RNAseq | 0.9115 | 0.0138 | |
| SRP193095 | KLHDC9 | 126823 | RNAseq | 0.0310 | 0.8777 | |
| SRP219564 | KLHDC9 | 126823 | RNAseq | -0.6717 | 0.3958 | |
| TCGA | KLHDC9 | 126823 | RNAseq | -0.6738 | 0.0326 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLHDC9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHDC9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHDC9 | 126823 | 10 | 0 | 20 | |
| GSE20123 | KLHDC9 | 126823 | 10 | 0 | 20 | |
| GSE43470 | KLHDC9 | 126823 | 7 | 2 | 34 | |
| GSE46452 | KLHDC9 | 126823 | 2 | 1 | 56 | |
| GSE47630 | KLHDC9 | 126823 | 14 | 0 | 26 | |
| GSE54993 | KLHDC9 | 126823 | 0 | 6 | 64 | |
| GSE54994 | KLHDC9 | 126823 | 16 | 0 | 37 | |
| GSE60625 | KLHDC9 | 126823 | 0 | 0 | 11 | |
| GSE74703 | KLHDC9 | 126823 | 7 | 2 | 27 | |
| GSE74704 | KLHDC9 | 126823 | 4 | 0 | 16 | |
| TCGA | KLHDC9 | 126823 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.
Somatic mutations of KLHDC9:
Generating mutation plots.
Highly correlated genes for KLHDC9:
Showing top 20/203 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHDC9 | MID2 | 0.747272 | 3 | 0 | 3 |
| KLHDC9 | ZBED5 | 0.735897 | 3 | 0 | 3 |
| KLHDC9 | KCNAB1 | 0.732902 | 3 | 0 | 3 |
| KLHDC9 | ARMCX2 | 0.730615 | 3 | 0 | 3 |
| KLHDC9 | SNX1 | 0.729737 | 3 | 0 | 3 |
| KLHDC9 | SOCS5 | 0.727085 | 3 | 0 | 3 |
| KLHDC9 | NHS | 0.726348 | 3 | 0 | 3 |
| KLHDC9 | ZNF10 | 0.725524 | 3 | 0 | 3 |
| KLHDC9 | FAM8A1 | 0.724312 | 3 | 0 | 3 |
| KLHDC9 | ECH1 | 0.723633 | 3 | 0 | 3 |
| KLHDC9 | TMEM30A | 0.721326 | 4 | 0 | 4 |
| KLHDC9 | AHCYL1 | 0.703514 | 3 | 0 | 3 |
| KLHDC9 | OCEL1 | 0.701858 | 3 | 0 | 3 |
| KLHDC9 | UHRF1BP1L | 0.699165 | 3 | 0 | 3 |
| KLHDC9 | RERE | 0.694849 | 3 | 0 | 3 |
| KLHDC9 | VDAC2 | 0.694193 | 3 | 0 | 3 |
| KLHDC9 | MFAP1 | 0.689532 | 3 | 0 | 3 |
| KLHDC9 | RFX2 | 0.682461 | 3 | 0 | 3 |
| KLHDC9 | ZNF862 | 0.680197 | 3 | 0 | 3 |
| KLHDC9 | HERC2 | 0.670016 | 3 | 0 | 3 |
For details and further investigation, click here
