| Full name: regulatory factor X2 | Alias Symbol: FLJ14226 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 5990 | HGNC ID: HGNC:9983 | Ensembl Gene: ENSG00000087903 | OMIM ID: 142765 |
| Drug and gene relationship at DGIdb | |||
Expression of RFX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFX2 | 5990 | 226872_at | -0.8881 | 0.0498 | |
| GSE20347 | RFX2 | 5990 | 208031_s_at | 0.1390 | 0.1214 | |
| GSE23400 | RFX2 | 5990 | 208031_s_at | -0.1663 | 0.0000 | |
| GSE26886 | RFX2 | 5990 | 208031_s_at | 0.3479 | 0.0108 | |
| GSE29001 | RFX2 | 5990 | 208031_s_at | -0.1141 | 0.4259 | |
| GSE38129 | RFX2 | 5990 | 208031_s_at | -0.0302 | 0.8251 | |
| GSE45670 | RFX2 | 5990 | 226872_at | -0.5205 | 0.0327 | |
| GSE53622 | RFX2 | 5990 | 69429 | -0.7123 | 0.0000 | |
| GSE53624 | RFX2 | 5990 | 69429 | -0.6985 | 0.0000 | |
| GSE63941 | RFX2 | 5990 | 226872_at | 0.0719 | 0.8730 | |
| GSE77861 | RFX2 | 5990 | 242966_x_at | 0.0322 | 0.8591 | |
| GSE97050 | RFX2 | 5990 | A_23_P502350 | -0.4337 | 0.2958 | |
| SRP007169 | RFX2 | 5990 | RNAseq | 0.7879 | 0.1439 | |
| SRP008496 | RFX2 | 5990 | RNAseq | 1.0175 | 0.0194 | |
| SRP064894 | RFX2 | 5990 | RNAseq | -0.6884 | 0.0484 | |
| SRP133303 | RFX2 | 5990 | RNAseq | -0.7171 | 0.0576 | |
| SRP159526 | RFX2 | 5990 | RNAseq | -0.9718 | 0.0888 | |
| SRP193095 | RFX2 | 5990 | RNAseq | 0.6910 | 0.0004 | |
| SRP219564 | RFX2 | 5990 | RNAseq | -0.2284 | 0.6815 | |
| TCGA | RFX2 | 5990 | RNAseq | -0.3813 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RFX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFX2 | 5990 | 5 | 3 | 22 | |
| GSE20123 | RFX2 | 5990 | 4 | 2 | 24 | |
| GSE43470 | RFX2 | 5990 | 2 | 6 | 35 | |
| GSE46452 | RFX2 | 5990 | 47 | 1 | 11 | |
| GSE47630 | RFX2 | 5990 | 5 | 7 | 28 | |
| GSE54993 | RFX2 | 5990 | 16 | 3 | 51 | |
| GSE54994 | RFX2 | 5990 | 6 | 16 | 31 | |
| GSE60625 | RFX2 | 5990 | 9 | 0 | 2 | |
| GSE74703 | RFX2 | 5990 | 2 | 4 | 30 | |
| GSE74704 | RFX2 | 5990 | 1 | 2 | 17 | |
| TCGA | RFX2 | 5990 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 63; Total Number of normals: 318.
Somatic mutations of RFX2:
Generating mutation plots.
Highly correlated genes for RFX2:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFX2 | TCL6 | 0.753182 | 3 | 0 | 3 |
| RFX2 | PPP1R15A | 0.746353 | 3 | 0 | 3 |
| RFX2 | HOXA3 | 0.743633 | 5 | 0 | 5 |
| RFX2 | ZNF358 | 0.736304 | 3 | 0 | 3 |
| RFX2 | EPN1 | 0.733888 | 4 | 0 | 4 |
| RFX2 | NUDT4 | 0.732623 | 3 | 0 | 3 |
| RFX2 | EDA2R | 0.72934 | 5 | 0 | 5 |
| RFX2 | CSF2 | 0.727356 | 4 | 0 | 4 |
| RFX2 | MAPRE3 | 0.714817 | 5 | 0 | 5 |
| RFX2 | RILP | 0.710011 | 3 | 0 | 3 |
| RFX2 | ING3 | 0.699292 | 3 | 0 | 3 |
| RFX2 | IL11 | 0.693247 | 4 | 0 | 3 |
| RFX2 | PLEKHA5 | 0.691823 | 4 | 0 | 3 |
| RFX2 | MEFV | 0.690596 | 3 | 0 | 3 |
| RFX2 | PROX1 | 0.69044 | 4 | 0 | 4 |
| RFX2 | SEMA6A | 0.689988 | 5 | 0 | 4 |
| RFX2 | SLC4A5 | 0.687231 | 4 | 0 | 3 |
| RFX2 | LCA5 | 0.685646 | 4 | 0 | 3 |
| RFX2 | EPOR | 0.685351 | 4 | 0 | 3 |
| RFX2 | DCAKD | 0.684034 | 5 | 0 | 4 |
For details and further investigation, click here
