| Full name: microfibril associated protein 1 | Alias Symbol: AMP | ||
| Type: protein-coding gene | Cytoband: 15q15.3 | ||
| Entrez ID: 4236 | HGNC ID: HGNC:7032 | Ensembl Gene: ENSG00000140259 | OMIM ID: 600215 |
| Drug and gene relationship at DGIdb | |||
Expression of MFAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFAP1 | 4236 | 203406_at | -0.1553 | 0.8121 | |
| GSE20347 | MFAP1 | 4236 | 203406_at | 0.0828 | 0.6461 | |
| GSE23400 | MFAP1 | 4236 | 203406_at | 0.1347 | 0.0027 | |
| GSE26886 | MFAP1 | 4236 | 203406_at | -0.2341 | 0.2147 | |
| GSE29001 | MFAP1 | 4236 | 203406_at | -0.0984 | 0.8048 | |
| GSE38129 | MFAP1 | 4236 | 203406_at | 0.1377 | 0.2927 | |
| GSE45670 | MFAP1 | 4236 | 203406_at | 0.1186 | 0.3100 | |
| GSE53622 | MFAP1 | 4236 | 54065 | 0.0547 | 0.5298 | |
| GSE53624 | MFAP1 | 4236 | 54065 | -0.0393 | 0.6991 | |
| GSE63941 | MFAP1 | 4236 | 203406_at | 0.0312 | 0.9310 | |
| GSE77861 | MFAP1 | 4236 | 203406_at | 0.0539 | 0.8200 | |
| GSE97050 | MFAP1 | 4236 | A_23_P14636 | -0.1161 | 0.5900 | |
| SRP007169 | MFAP1 | 4236 | RNAseq | 0.7159 | 0.1426 | |
| SRP064894 | MFAP1 | 4236 | RNAseq | -0.0830 | 0.5654 | |
| SRP133303 | MFAP1 | 4236 | RNAseq | 0.0802 | 0.5791 | |
| SRP159526 | MFAP1 | 4236 | RNAseq | -0.0541 | 0.8781 | |
| SRP193095 | MFAP1 | 4236 | RNAseq | 0.0270 | 0.8675 | |
| SRP219564 | MFAP1 | 4236 | RNAseq | -0.7127 | 0.0228 | |
| TCGA | MFAP1 | 4236 | RNAseq | 0.0284 | 0.5846 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MFAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MFAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFAP1 | 4236 | 3 | 4 | 23 | |
| GSE20123 | MFAP1 | 4236 | 3 | 5 | 22 | |
| GSE43470 | MFAP1 | 4236 | 3 | 4 | 36 | |
| GSE46452 | MFAP1 | 4236 | 3 | 7 | 49 | |
| GSE47630 | MFAP1 | 4236 | 8 | 10 | 22 | |
| GSE54993 | MFAP1 | 4236 | 4 | 6 | 60 | |
| GSE54994 | MFAP1 | 4236 | 5 | 7 | 41 | |
| GSE60625 | MFAP1 | 4236 | 4 | 0 | 7 | |
| GSE74703 | MFAP1 | 4236 | 3 | 3 | 30 | |
| GSE74704 | MFAP1 | 4236 | 2 | 2 | 16 | |
| TCGA | MFAP1 | 4236 | 12 | 17 | 67 |
Total number of gains: 50; Total number of losses: 65; Total Number of normals: 373.
Somatic mutations of MFAP1:
Generating mutation plots.
Highly correlated genes for MFAP1:
Showing top 20/570 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFAP1 | UBE2L3 | 0.758771 | 3 | 0 | 3 |
| MFAP1 | VDAC2 | 0.748084 | 3 | 0 | 3 |
| MFAP1 | APIP | 0.74429 | 3 | 0 | 3 |
| MFAP1 | ALDOC | 0.731465 | 4 | 0 | 3 |
| MFAP1 | RBAK | 0.731241 | 3 | 0 | 3 |
| MFAP1 | ATF6 | 0.72626 | 3 | 0 | 3 |
| MFAP1 | ATP11B | 0.722044 | 3 | 0 | 3 |
| MFAP1 | TMEM60 | 0.720343 | 4 | 0 | 3 |
| MFAP1 | KANSL2 | 0.717433 | 4 | 0 | 4 |
| MFAP1 | RSL24D1 | 0.710125 | 9 | 0 | 7 |
| MFAP1 | SMU1 | 0.709442 | 5 | 0 | 5 |
| MFAP1 | SLC16A14 | 0.703188 | 3 | 0 | 3 |
| MFAP1 | CYFIP1 | 0.702902 | 7 | 0 | 7 |
| MFAP1 | WTAP | 0.700131 | 5 | 0 | 4 |
| MFAP1 | MRPS11 | 0.700051 | 7 | 0 | 6 |
| MFAP1 | CALCRL | 0.69608 | 4 | 0 | 3 |
| MFAP1 | AMD1 | 0.695287 | 4 | 0 | 3 |
| MFAP1 | CNOT1 | 0.690744 | 4 | 0 | 4 |
| MFAP1 | KLHDC9 | 0.689532 | 3 | 0 | 3 |
| MFAP1 | SOX2 | 0.688313 | 4 | 0 | 3 |
For details and further investigation, click here
