| Full name: collagen type IX alpha 2 chain | Alias Symbol: MED | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 1298 | HGNC ID: HGNC:2218 | Ensembl Gene: ENSG00000049089 | OMIM ID: 120260 |
| Drug and gene relationship at DGIdb | |||
COL9A2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04151 | PI3K-Akt signaling pathway | |
| hsa04510 | Focal adhesion |
Expression of COL9A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COL9A2 | 1298 | 213622_at | 1.1035 | 0.0366 | |
| GSE20347 | COL9A2 | 1298 | 213622_at | 0.5684 | 0.0143 | |
| GSE23400 | COL9A2 | 1298 | 213622_at | 0.1954 | 0.0510 | |
| GSE26886 | COL9A2 | 1298 | 232542_at | -0.1325 | 0.3238 | |
| GSE29001 | COL9A2 | 1298 | 213622_at | 0.4668 | 0.1733 | |
| GSE38129 | COL9A2 | 1298 | 213622_at | 0.3993 | 0.0321 | |
| GSE45670 | COL9A2 | 1298 | 213622_at | 0.2401 | 0.0390 | |
| GSE53622 | COL9A2 | 1298 | 105625 | 1.4445 | 0.0000 | |
| GSE53624 | COL9A2 | 1298 | 105625 | 1.3537 | 0.0000 | |
| GSE63941 | COL9A2 | 1298 | 232542_at | 0.3058 | 0.2099 | |
| GSE77861 | COL9A2 | 1298 | 232542_at | -0.1767 | 0.0751 | |
| GSE97050 | COL9A2 | 1298 | A_23_P45786 | 0.5422 | 0.2062 | |
| SRP007169 | COL9A2 | 1298 | RNAseq | 4.3991 | 0.0002 | |
| SRP064894 | COL9A2 | 1298 | RNAseq | 1.3894 | 0.0000 | |
| SRP133303 | COL9A2 | 1298 | RNAseq | 1.0326 | 0.0060 | |
| SRP193095 | COL9A2 | 1298 | RNAseq | 1.6640 | 0.0002 | |
| SRP219564 | COL9A2 | 1298 | RNAseq | 2.0279 | 0.0030 | |
| TCGA | COL9A2 | 1298 | RNAseq | -0.0645 | 0.7880 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by COL9A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COL9A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COL9A2 | 1298 | 3 | 4 | 23 | |
| GSE20123 | COL9A2 | 1298 | 2 | 3 | 25 | |
| GSE43470 | COL9A2 | 1298 | 7 | 2 | 34 | |
| GSE46452 | COL9A2 | 1298 | 4 | 1 | 54 | |
| GSE47630 | COL9A2 | 1298 | 9 | 2 | 29 | |
| GSE54993 | COL9A2 | 1298 | 0 | 1 | 69 | |
| GSE54994 | COL9A2 | 1298 | 13 | 2 | 38 | |
| GSE60625 | COL9A2 | 1298 | 0 | 0 | 11 | |
| GSE74703 | COL9A2 | 1298 | 6 | 1 | 29 | |
| GSE74704 | COL9A2 | 1298 | 1 | 0 | 19 | |
| TCGA | COL9A2 | 1298 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 32; Total Number of normals: 395.
Somatic mutations of COL9A2:
Generating mutation plots.
Highly correlated genes for COL9A2:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COL9A2 | KRT7 | 0.72708 | 3 | 0 | 3 |
| COL9A2 | KLLN | 0.69334 | 3 | 0 | 3 |
| COL9A2 | PLOD1 | 0.683271 | 5 | 0 | 5 |
| COL9A2 | UNC79 | 0.682563 | 3 | 0 | 3 |
| COL9A2 | OR52A1 | 0.674146 | 3 | 0 | 3 |
| COL9A2 | CST2 | 0.6631 | 5 | 0 | 4 |
| COL9A2 | KIR2DS1 | 0.657735 | 3 | 0 | 3 |
| COL9A2 | STARD3 | 0.657601 | 3 | 0 | 3 |
| COL9A2 | MUC2 | 0.65523 | 3 | 0 | 3 |
| COL9A2 | RBBP4 | 0.636463 | 5 | 0 | 4 |
| COL9A2 | CA14 | 0.635889 | 3 | 0 | 3 |
| COL9A2 | CCDC157 | 0.632839 | 3 | 0 | 3 |
| COL9A2 | FIZ1 | 0.630024 | 4 | 0 | 3 |
| COL9A2 | GRIN2A | 0.630023 | 3 | 0 | 3 |
| COL9A2 | CD320 | 0.623403 | 4 | 0 | 3 |
| COL9A2 | ARHGAP25 | 0.619133 | 3 | 0 | 3 |
| COL9A2 | ICOSLG | 0.61698 | 3 | 0 | 3 |
| COL9A2 | KRTAP8-1 | 0.61691 | 3 | 0 | 3 |
| COL9A2 | IFT122 | 0.615921 | 6 | 0 | 5 |
| COL9A2 | NPTX2 | 0.615028 | 5 | 0 | 4 |
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