| Full name: formin 1 | Alias Symbol: DKFZP686C2281|FLJ45135|MGC125288|MGC125289 | ||
| Type: protein-coding gene | Cytoband: 15q13.3 | ||
| Entrez ID: 342184 | HGNC ID: HGNC:3768 | Ensembl Gene: ENSG00000248905 | OMIM ID: 136535 |
| Drug and gene relationship at DGIdb | |||
Expression of FMN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMN1 | 342184 | 238621_at | -0.6864 | 0.1661 | |
| GSE26886 | FMN1 | 342184 | 238621_at | -0.8879 | 0.0000 | |
| GSE45670 | FMN1 | 342184 | 238621_at | -0.3231 | 0.0164 | |
| GSE53622 | FMN1 | 342184 | 33374 | -0.6321 | 0.0000 | |
| GSE53624 | FMN1 | 342184 | 33374 | -0.3369 | 0.0000 | |
| GSE63941 | FMN1 | 342184 | 1570156_s_at | 0.4346 | 0.1285 | |
| GSE77861 | FMN1 | 342184 | 1570156_s_at | -0.2916 | 0.0156 | |
| GSE97050 | FMN1 | 342184 | A_33_P3404749 | 0.4548 | 0.4794 | |
| SRP007169 | FMN1 | 342184 | RNAseq | -0.4024 | 0.4426 | |
| SRP008496 | FMN1 | 342184 | RNAseq | 0.1909 | 0.5679 | |
| SRP064894 | FMN1 | 342184 | RNAseq | -0.0505 | 0.8883 | |
| SRP133303 | FMN1 | 342184 | RNAseq | -0.1529 | 0.5160 | |
| SRP159526 | FMN1 | 342184 | RNAseq | -0.4803 | 0.2528 | |
| SRP193095 | FMN1 | 342184 | RNAseq | -0.4078 | 0.1236 | |
| SRP219564 | FMN1 | 342184 | RNAseq | 0.7871 | 0.1125 | |
| TCGA | FMN1 | 342184 | RNAseq | -0.8610 | 0.0003 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FMN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FMN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FMN1 | 342184 | 2 | 7 | 21 | |
| GSE20123 | FMN1 | 342184 | 2 | 7 | 21 | |
| GSE43470 | FMN1 | 342184 | 4 | 4 | 35 | |
| GSE46452 | FMN1 | 342184 | 3 | 7 | 49 | |
| GSE47630 | FMN1 | 342184 | 8 | 11 | 21 | |
| GSE54993 | FMN1 | 342184 | 4 | 6 | 60 | |
| GSE54994 | FMN1 | 342184 | 5 | 9 | 39 | |
| GSE60625 | FMN1 | 342184 | 4 | 0 | 7 | |
| GSE74703 | FMN1 | 342184 | 4 | 3 | 29 | |
| GSE74704 | FMN1 | 342184 | 1 | 6 | 13 | |
| TCGA | FMN1 | 342184 | 13 | 17 | 66 |
Total number of gains: 50; Total number of losses: 77; Total Number of normals: 361.
Somatic mutations of FMN1:
Generating mutation plots.
Highly correlated genes for FMN1:
Showing top 20/650 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMN1 | LINC00315 | 0.76826 | 3 | 0 | 3 |
| FMN1 | SNORA68 | 0.711824 | 4 | 0 | 4 |
| FMN1 | CD1C | 0.70506 | 4 | 0 | 4 |
| FMN1 | CLIC3 | 0.699647 | 4 | 0 | 4 |
| FMN1 | FCRLA | 0.695866 | 4 | 0 | 4 |
| FMN1 | RBP5 | 0.695626 | 3 | 0 | 3 |
| FMN1 | SFTA2 | 0.693284 | 5 | 0 | 5 |
| FMN1 | P2RY10 | 0.685699 | 4 | 0 | 4 |
| FMN1 | RBKS | 0.684847 | 3 | 0 | 3 |
| FMN1 | GBP4 | 0.68399 | 3 | 0 | 3 |
| FMN1 | SPNS2 | 0.68397 | 4 | 0 | 4 |
| FMN1 | ITGAD | 0.681065 | 5 | 0 | 5 |
| FMN1 | A1CF | 0.678149 | 4 | 0 | 3 |
| FMN1 | GBP6 | 0.677944 | 5 | 0 | 5 |
| FMN1 | SPATA18 | 0.670565 | 5 | 0 | 4 |
| FMN1 | UBL3 | 0.669661 | 5 | 0 | 5 |
| FMN1 | TNFAIP8L2 | 0.667781 | 3 | 0 | 3 |
| FMN1 | ABLIM1 | 0.667476 | 6 | 0 | 5 |
| FMN1 | TRIM22 | 0.666024 | 3 | 0 | 3 |
| FMN1 | TOM1L2 | 0.664026 | 4 | 0 | 3 |
For details and further investigation, click here
