NMUR2

 

Full name: neuromedin U receptor 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 5q33.1
Entrez ID: 56923 HGNC ID: HGNC:16454 Ensembl Gene: ENSG00000132911 OMIM ID: 605108
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of NMUR2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NMUR2 56923 224088_at 0.0262 0.9479
GSE26886 NMUR2 56923 224088_at -0.2398 0.1001
GSE45670 NMUR2 56923 224088_at 0.1639 0.1884
GSE53622 NMUR2 56923 13217 0.5206 0.0002
GSE53624 NMUR2 56923 13217 0.7120 0.0000
GSE63941 NMUR2 56923 224088_at 0.0822 0.6874
GSE77861 NMUR2 56923 224088_at -0.1625 0.1256
GSE97050 NMUR2 56923 A_23_P122134 -0.1083 0.6706
TCGA NMUR2 56923 RNAseq 0.0442 0.9524

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by NMUR2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NMUR2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NMUR2 56923 1 12 17
GSE20123 NMUR2 56923 1 12 17
GSE43470 NMUR2 56923 2 10 31
GSE46452 NMUR2 56923 0 27 32
GSE47630 NMUR2 56923 0 20 20
GSE54993 NMUR2 56923 9 1 60
GSE54994 NMUR2 56923 1 16 36
GSE60625 NMUR2 56923 0 0 11
GSE74703 NMUR2 56923 2 8 26
GSE74704 NMUR2 56923 1 7 12
TCGA NMUR2 56923 5 37 54

Total number of gains: 22; Total number of losses: 150; Total Number of normals: 316.  


 

Somatic mutations of NMUR2:

 

Generating mutation plots.

 

Highly correlated genes for NMUR2:

 

Showing top 20/136 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NMUR2HAND10.724101303
NMUR2TTR0.709702303
NMUR2AQP90.675949303
NMUR2KIRREL3-AS30.667431404
NMUR2CELA3A0.664458404
NMUR2EPOR0.661829403
NMUR2KLLN0.660773403
NMUR2GLT1D10.656666303
NMUR2PRSS330.646403303
NMUR2CSRP30.637163303
NMUR2LINC011920.635996303
NMUR2ANHX0.63301403
NMUR2KRT820.631454303
NMUR2GPR750.628569303
NMUR2FLVCR20.628351303
NMUR2MPV17L0.624929404
NMUR2SPATA320.624436303
NMUR2ASCL30.619868403
NMUR2RETNLB0.616012303
NMUR2DCST10.614185303

For details and further investigation, click here