| Full name: small proline rich protein 4 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 163778 | HGNC ID: HGNC:23173 | Ensembl Gene: ENSG00000184148 | OMIM ID: 616363 |
Expression of SPRR4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRR4 | 163778 | 1552620_at | 0.1130 | 0.8772 | |
| GSE26886 | SPRR4 | 163778 | 1552620_at | -0.3913 | 0.0882 | |
| GSE45670 | SPRR4 | 163778 | 1552620_at | 1.2034 | 0.0019 | |
| GSE63941 | SPRR4 | 163778 | 1552620_at | 0.2944 | 0.1154 | |
| GSE77861 | SPRR4 | 163778 | 1552620_at | 0.3091 | 0.2891 | |
| GSE97050 | SPRR4 | 163778 | A_23_P422018 | 1.2352 | 0.2385 | |
| TCGA | SPRR4 | 163778 | RNAseq | 2.6554 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SPRR4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of SPRR4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRR4 | 163778 | 15 | 0 | 15 | |
| GSE20123 | SPRR4 | 163778 | 15 | 0 | 15 | |
| GSE43470 | SPRR4 | 163778 | 6 | 2 | 35 | |
| GSE46452 | SPRR4 | 163778 | 3 | 1 | 55 | |
| GSE47630 | SPRR4 | 163778 | 15 | 0 | 25 | |
| GSE54993 | SPRR4 | 163778 | 0 | 4 | 66 | |
| GSE54994 | SPRR4 | 163778 | 15 | 0 | 38 | |
| GSE60625 | SPRR4 | 163778 | 0 | 0 | 11 | |
| GSE74703 | SPRR4 | 163778 | 6 | 1 | 29 | |
| GSE74704 | SPRR4 | 163778 | 7 | 0 | 13 | |
| TCGA | SPRR4 | 163778 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of SPRR4:
Generating mutation plots.
Highly correlated genes for SPRR4:
Showing top 20/89 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRR4 | IDH3A | 0.775954 | 3 | 0 | 3 |
| SPRR4 | CDSN | 0.718119 | 5 | 0 | 5 |
| SPRR4 | GAB4 | 0.707677 | 3 | 0 | 3 |
| SPRR4 | IL36G | 0.703707 | 4 | 0 | 4 |
| SPRR4 | RHO | 0.698116 | 3 | 0 | 3 |
| SPRR4 | KLLN | 0.692837 | 3 | 0 | 3 |
| SPRR4 | PCAT19 | 0.690171 | 3 | 0 | 3 |
| SPRR4 | LCE1E | 0.6854 | 3 | 0 | 3 |
| SPRR4 | ODC1 | 0.67993 | 3 | 0 | 3 |
| SPRR4 | LACTB2 | 0.673511 | 3 | 0 | 3 |
| SPRR4 | HYAL1 | 0.672972 | 3 | 0 | 3 |
| SPRR4 | WFDC5 | 0.672251 | 3 | 0 | 3 |
| SPRR4 | NCOA7 | 0.666715 | 3 | 0 | 3 |
| SPRR4 | SLC34A3 | 0.641222 | 3 | 0 | 3 |
| SPRR4 | ABCA12 | 0.638102 | 4 | 0 | 3 |
| SPRR4 | DNAH1 | 0.636561 | 3 | 0 | 3 |
| SPRR4 | OR4D2 | 0.634616 | 3 | 0 | 3 |
| SPRR4 | SLC4A1 | 0.62284 | 3 | 0 | 3 |
| SPRR4 | TSSK3 | 0.619765 | 4 | 0 | 3 |
| SPRR4 | CEACAM19 | 0.618131 | 5 | 0 | 4 |
For details and further investigation, click here
