| Full name: monocyte to macrophage differentiation associated 2 | Alias Symbol: PAQR10 | ||
| Type: protein-coding gene | Cytoband: 7p22.1 | ||
| Entrez ID: 221938 | HGNC ID: HGNC:30133 | Ensembl Gene: ENSG00000136297 | OMIM ID: 614581 |
| Drug and gene relationship at DGIdb | |||
Expression of MMD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MMD2 | 221938 | 230826_at | 0.0012 | 0.9966 | |
| GSE26886 | MMD2 | 221938 | 230826_at | 0.0064 | 0.9739 | |
| GSE45670 | MMD2 | 221938 | 230826_at | -0.0236 | 0.8385 | |
| GSE53622 | MMD2 | 221938 | 115999 | 0.2306 | 0.0112 | |
| GSE53624 | MMD2 | 221938 | 115999 | 0.2929 | 0.0018 | |
| GSE63941 | MMD2 | 221938 | 230826_at | 0.2995 | 0.0661 | |
| GSE77861 | MMD2 | 221938 | 230826_at | -0.2760 | 0.1100 | |
| TCGA | MMD2 | 221938 | RNAseq | -3.0284 | 0.0907 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MMD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MMD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MMD2 | 221938 | 14 | 1 | 15 | |
| GSE20123 | MMD2 | 221938 | 14 | 1 | 15 | |
| GSE43470 | MMD2 | 221938 | 6 | 1 | 36 | |
| GSE46452 | MMD2 | 221938 | 13 | 1 | 45 | |
| GSE47630 | MMD2 | 221938 | 9 | 1 | 30 | |
| GSE54993 | MMD2 | 221938 | 0 | 6 | 64 | |
| GSE54994 | MMD2 | 221938 | 22 | 2 | 29 | |
| GSE60625 | MMD2 | 221938 | 0 | 0 | 11 | |
| GSE74703 | MMD2 | 221938 | 6 | 0 | 30 | |
| GSE74704 | MMD2 | 221938 | 9 | 0 | 11 | |
| TCGA | MMD2 | 221938 | 56 | 5 | 35 |
Total number of gains: 149; Total number of losses: 18; Total Number of normals: 321.
Somatic mutations of MMD2:
Generating mutation plots.
Highly correlated genes for MMD2:
Showing top 20/139 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MMD2 | F11 | 0.725988 | 3 | 0 | 3 |
| MMD2 | LRTM2 | 0.699639 | 4 | 0 | 4 |
| MMD2 | ADAMTS7 | 0.689021 | 3 | 0 | 3 |
| MMD2 | KCNF1 | 0.664461 | 3 | 0 | 3 |
| MMD2 | RS1 | 0.663312 | 3 | 0 | 3 |
| MMD2 | TMEM106A | 0.658862 | 3 | 0 | 3 |
| MMD2 | HUS1B | 0.658065 | 3 | 0 | 3 |
| MMD2 | GALNT9 | 0.656187 | 3 | 0 | 3 |
| MMD2 | GPHB5 | 0.654376 | 3 | 0 | 3 |
| MMD2 | WDR38 | 0.65427 | 3 | 0 | 3 |
| MMD2 | DOK3 | 0.648508 | 4 | 0 | 4 |
| MMD2 | DNAH7 | 0.648108 | 3 | 0 | 3 |
| MMD2 | SFRP5 | 0.647312 | 3 | 0 | 3 |
| MMD2 | MYBPC3 | 0.645384 | 4 | 0 | 3 |
| MMD2 | GIPC3 | 0.641426 | 4 | 0 | 4 |
| MMD2 | PSKH2 | 0.64085 | 3 | 0 | 3 |
| MMD2 | ABI3 | 0.637848 | 4 | 0 | 3 |
| MMD2 | KRT72 | 0.635696 | 3 | 0 | 3 |
| MMD2 | TM6SF2 | 0.63446 | 3 | 0 | 3 |
| MMD2 | DPEP3 | 0.633986 | 5 | 0 | 4 |
For details and further investigation, click here
