| Full name: keratin 24 | Alias Symbol: FLJ20261|MGC138169|MGC138173 | ||
| Type: protein-coding gene | Cytoband: 17q21.2 | ||
| Entrez ID: 192666 | HGNC ID: HGNC:18527 | Ensembl Gene: ENSG00000167916 | OMIM ID: 607742 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT24 | 192666 | 220267_at | -1.3423 | 0.7140 | |
| GSE20347 | KRT24 | 192666 | 220267_at | -2.3003 | 0.0085 | |
| GSE23400 | KRT24 | 192666 | 220267_at | -1.5864 | 0.0000 | |
| GSE26886 | KRT24 | 192666 | 220267_at | -4.5403 | 0.0000 | |
| GSE29001 | KRT24 | 192666 | 220267_at | -1.5296 | 0.0719 | |
| GSE38129 | KRT24 | 192666 | 220267_at | -2.2729 | 0.0004 | |
| GSE45670 | KRT24 | 192666 | 220267_at | 0.4608 | 0.7172 | |
| GSE53622 | KRT24 | 192666 | 97884 | -1.7617 | 0.0000 | |
| GSE53624 | KRT24 | 192666 | 97884 | -1.8489 | 0.0000 | |
| GSE63941 | KRT24 | 192666 | 220267_at | 0.1376 | 0.3715 | |
| GSE77861 | KRT24 | 192666 | 220267_at | -2.0735 | 0.2167 | |
| GSE97050 | KRT24 | 192666 | A_23_P4387 | -0.7243 | 0.2067 | |
| SRP064894 | KRT24 | 192666 | RNAseq | -3.1488 | 0.0000 | |
| SRP159526 | KRT24 | 192666 | RNAseq | -5.1286 | 0.0000 | |
| TCGA | KRT24 | 192666 | RNAseq | -0.4619 | 0.6346 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by KRT24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT24 | 192666 | 7 | 1 | 22 | |
| GSE20123 | KRT24 | 192666 | 7 | 1 | 22 | |
| GSE43470 | KRT24 | 192666 | 1 | 2 | 40 | |
| GSE46452 | KRT24 | 192666 | 34 | 0 | 25 | |
| GSE47630 | KRT24 | 192666 | 8 | 1 | 31 | |
| GSE54993 | KRT24 | 192666 | 3 | 4 | 63 | |
| GSE54994 | KRT24 | 192666 | 8 | 5 | 40 | |
| GSE60625 | KRT24 | 192666 | 4 | 0 | 7 | |
| GSE74703 | KRT24 | 192666 | 1 | 1 | 34 | |
| GSE74704 | KRT24 | 192666 | 5 | 1 | 14 | |
| TCGA | KRT24 | 192666 | 22 | 8 | 66 |
Total number of gains: 100; Total number of losses: 24; Total Number of normals: 364.
Somatic mutations of KRT24:
Generating mutation plots.
Highly correlated genes for KRT24:
Showing top 20/405 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT24 | OTOP3 | 0.694456 | 3 | 0 | 3 |
| KRT24 | CYP3A7 | 0.693892 | 3 | 0 | 3 |
| KRT24 | TMPRSS11A | 0.691208 | 4 | 0 | 4 |
| KRT24 | KLKB1 | 0.689175 | 3 | 0 | 3 |
| KRT24 | KRTAP20-1 | 0.687541 | 3 | 0 | 3 |
| KRT24 | ATP12A | 0.678365 | 4 | 0 | 3 |
| KRT24 | CAPN14 | 0.673425 | 6 | 0 | 6 |
| KRT24 | NCCRP1 | 0.671864 | 4 | 0 | 4 |
| KRT24 | SEC24A | 0.670927 | 3 | 0 | 3 |
| KRT24 | LYNX1 | 0.668533 | 7 | 0 | 7 |
| KRT24 | SLC15A1 | 0.663793 | 3 | 0 | 3 |
| KRT24 | CEACAM1 | 0.662676 | 12 | 0 | 11 |
| KRT24 | FAM163B | 0.662589 | 3 | 0 | 3 |
| KRT24 | TMPRSS11B | 0.662522 | 7 | 0 | 7 |
| KRT24 | VSIG10L | 0.66204 | 6 | 0 | 6 |
| KRT24 | PRSS27 | 0.662009 | 8 | 0 | 7 |
| KRT24 | CLCA4 | 0.656468 | 11 | 0 | 11 |
| KRT24 | CEACAM7 | 0.649006 | 11 | 0 | 10 |
| KRT24 | SLC35F3 | 0.64484 | 3 | 0 | 3 |
| KRT24 | ZNF501 | 0.642397 | 3 | 0 | 3 |
For details and further investigation, click here
