| Full name: solute carrier family 15 member 1 | Alias Symbol: PEPT1|HPECT1|HPEPT1 | ||
| Type: protein-coding gene | Cytoband: 13q32.2-q32.3 | ||
| Entrez ID: 6564 | HGNC ID: HGNC:10920 | Ensembl Gene: ENSG00000088386 | OMIM ID: 600544 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC15A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC15A1 | 6564 | 207254_at | -0.1817 | 0.5500 | |
| GSE20347 | SLC15A1 | 6564 | 207254_at | 0.0257 | 0.8997 | |
| GSE23400 | SLC15A1 | 6564 | 211349_at | -0.0236 | 0.4343 | |
| GSE26886 | SLC15A1 | 6564 | 207254_at | -0.9670 | 0.0004 | |
| GSE29001 | SLC15A1 | 6564 | 211349_at | 0.0030 | 0.9853 | |
| GSE38129 | SLC15A1 | 6564 | 207254_at | 0.1737 | 0.2274 | |
| GSE45670 | SLC15A1 | 6564 | 207254_at | 1.1018 | 0.0017 | |
| GSE53622 | SLC15A1 | 6564 | 28026 | -0.0058 | 0.9816 | |
| GSE53624 | SLC15A1 | 6564 | 28026 | -0.2507 | 0.1925 | |
| GSE63941 | SLC15A1 | 6564 | 207254_at | 0.2432 | 0.4151 | |
| GSE77861 | SLC15A1 | 6564 | 211349_at | -0.0565 | 0.6580 | |
| GSE97050 | SLC15A1 | 6564 | A_33_P3373273 | 0.5073 | 0.3751 | |
| SRP007169 | SLC15A1 | 6564 | RNAseq | 0.7691 | 0.3041 | |
| SRP064894 | SLC15A1 | 6564 | RNAseq | 0.1609 | 0.7558 | |
| SRP133303 | SLC15A1 | 6564 | RNAseq | 1.1934 | 0.0025 | |
| SRP159526 | SLC15A1 | 6564 | RNAseq | 0.9395 | 0.0731 | |
| SRP193095 | SLC15A1 | 6564 | RNAseq | 0.1422 | 0.5948 | |
| SRP219564 | SLC15A1 | 6564 | RNAseq | 0.1103 | 0.8828 | |
| TCGA | SLC15A1 | 6564 | RNAseq | 0.8387 | 0.0401 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by SLC15A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC15A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC15A1 | 6564 | 3 | 8 | 19 | |
| GSE20123 | SLC15A1 | 6564 | 3 | 8 | 19 | |
| GSE43470 | SLC15A1 | 6564 | 4 | 12 | 27 | |
| GSE46452 | SLC15A1 | 6564 | 0 | 32 | 27 | |
| GSE47630 | SLC15A1 | 6564 | 3 | 26 | 11 | |
| GSE54993 | SLC15A1 | 6564 | 11 | 4 | 55 | |
| GSE54994 | SLC15A1 | 6564 | 3 | 12 | 38 | |
| GSE60625 | SLC15A1 | 6564 | 0 | 3 | 8 | |
| GSE74703 | SLC15A1 | 6564 | 3 | 10 | 23 | |
| GSE74704 | SLC15A1 | 6564 | 1 | 7 | 12 | |
| TCGA | SLC15A1 | 6564 | 16 | 34 | 46 |
Total number of gains: 47; Total number of losses: 156; Total Number of normals: 285.
Somatic mutations of SLC15A1:
Generating mutation plots.
Highly correlated genes for SLC15A1:
Showing top 20/156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC15A1 | PRSS2 | 0.706026 | 3 | 0 | 3 |
| SLC15A1 | SLC5A4 | 0.697864 | 3 | 0 | 3 |
| SLC15A1 | PTPRCAP | 0.695658 | 3 | 0 | 3 |
| SLC15A1 | KIR3DL3 | 0.692537 | 3 | 0 | 3 |
| SLC15A1 | CR2 | 0.673234 | 3 | 0 | 3 |
| SLC15A1 | SIGLEC7 | 0.672416 | 4 | 0 | 4 |
| SLC15A1 | TNFSF11 | 0.669018 | 3 | 0 | 3 |
| SLC15A1 | KRT24 | 0.663793 | 3 | 0 | 3 |
| SLC15A1 | IL9R | 0.661338 | 3 | 0 | 3 |
| SLC15A1 | PIWIL2 | 0.660128 | 4 | 0 | 3 |
| SLC15A1 | CACNG3 | 0.65385 | 3 | 0 | 3 |
| SLC15A1 | DIO2 | 0.650374 | 3 | 0 | 3 |
| SLC15A1 | MAG | 0.647202 | 3 | 0 | 3 |
| SLC15A1 | ADRA1A | 0.645446 | 4 | 0 | 4 |
| SLC15A1 | PPP1R14D | 0.645231 | 4 | 0 | 3 |
| SLC15A1 | CDC25C | 0.644476 | 4 | 0 | 3 |
| SLC15A1 | REG3A | 0.643902 | 3 | 0 | 3 |
| SLC15A1 | DND1 | 0.643648 | 4 | 0 | 3 |
| SLC15A1 | AQP8 | 0.643109 | 3 | 0 | 3 |
| SLC15A1 | PRODH2 | 0.642751 | 3 | 0 | 3 |
For details and further investigation, click here
