| Full name: SEC24 homolog A, COPII coat complex component | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 10802 | HGNC ID: HGNC:10703 | Ensembl Gene: ENSG00000113615 | OMIM ID: 607183 |
| Drug and gene relationship at DGIdb | |||
Expression of SEC24A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC24A | 10802 | 212900_at | -0.1215 | 0.8483 | |
| GSE20347 | SEC24A | 10802 | 212900_at | -0.3450 | 0.0322 | |
| GSE23400 | SEC24A | 10802 | 212900_at | -0.2494 | 0.0010 | |
| GSE26886 | SEC24A | 10802 | 212900_at | -1.2438 | 0.0000 | |
| GSE29001 | SEC24A | 10802 | 212900_at | -0.3761 | 0.1534 | |
| GSE38129 | SEC24A | 10802 | 212900_at | -0.2426 | 0.1059 | |
| GSE45670 | SEC24A | 10802 | 212900_at | 0.1975 | 0.2785 | |
| GSE53622 | SEC24A | 10802 | 67463 | -0.3822 | 0.0001 | |
| GSE53624 | SEC24A | 10802 | 67463 | -0.5671 | 0.0000 | |
| GSE63941 | SEC24A | 10802 | 212900_at | -1.2768 | 0.0047 | |
| GSE77861 | SEC24A | 10802 | 212900_at | -0.4396 | 0.2608 | |
| GSE97050 | SEC24A | 10802 | A_33_P3331080 | -0.0170 | 0.9627 | |
| SRP007169 | SEC24A | 10802 | RNAseq | -1.0773 | 0.0032 | |
| SRP008496 | SEC24A | 10802 | RNAseq | -1.1336 | 0.0000 | |
| SRP064894 | SEC24A | 10802 | RNAseq | -0.4243 | 0.0821 | |
| SRP133303 | SEC24A | 10802 | RNAseq | 0.2584 | 0.1121 | |
| SRP159526 | SEC24A | 10802 | RNAseq | -0.5309 | 0.2119 | |
| SRP193095 | SEC24A | 10802 | RNAseq | -0.6467 | 0.0000 | |
| SRP219564 | SEC24A | 10802 | RNAseq | -0.0766 | 0.8781 | |
| TCGA | SEC24A | 10802 | RNAseq | -0.2186 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SEC24A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC24A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC24A | 10802 | 3 | 11 | 16 | |
| GSE20123 | SEC24A | 10802 | 4 | 11 | 15 | |
| GSE43470 | SEC24A | 10802 | 2 | 8 | 33 | |
| GSE46452 | SEC24A | 10802 | 0 | 27 | 32 | |
| GSE47630 | SEC24A | 10802 | 0 | 21 | 19 | |
| GSE54993 | SEC24A | 10802 | 9 | 1 | 60 | |
| GSE54994 | SEC24A | 10802 | 2 | 14 | 37 | |
| GSE60625 | SEC24A | 10802 | 0 | 0 | 11 | |
| GSE74703 | SEC24A | 10802 | 2 | 5 | 29 | |
| GSE74704 | SEC24A | 10802 | 3 | 5 | 12 | |
| TCGA | SEC24A | 10802 | 3 | 36 | 57 |
Total number of gains: 28; Total number of losses: 139; Total Number of normals: 321.
Somatic mutations of SEC24A:
Generating mutation plots.
Highly correlated genes for SEC24A:
Showing top 20/167 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC24A | DAPL1 | 0.687397 | 3 | 0 | 3 |
| SEC24A | KRT24 | 0.670927 | 3 | 0 | 3 |
| SEC24A | SAR1B | 0.666096 | 12 | 0 | 11 |
| SEC24A | UBE2D3 | 0.659856 | 4 | 0 | 4 |
| SEC24A | TMLHE | 0.646258 | 4 | 0 | 4 |
| SEC24A | MGAT1 | 0.645107 | 5 | 0 | 4 |
| SEC24A | ZCCHC18 | 0.63273 | 3 | 0 | 3 |
| SEC24A | CMTR2 | 0.630936 | 6 | 0 | 5 |
| SEC24A | VSIG10L | 0.619288 | 4 | 0 | 3 |
| SEC24A | RAB10 | 0.61153 | 4 | 0 | 3 |
| SEC24A | NCKAP5 | 0.609228 | 5 | 0 | 4 |
| SEC24A | PPP2CA | 0.606278 | 9 | 0 | 6 |
| SEC24A | RCAN3 | 0.604721 | 3 | 0 | 3 |
| SEC24A | LATS2 | 0.601129 | 4 | 0 | 4 |
| SEC24A | ROBO2 | 0.599048 | 4 | 0 | 3 |
| SEC24A | CAPN14 | 0.597531 | 4 | 0 | 3 |
| SEC24A | LINC00892 | 0.595234 | 4 | 0 | 4 |
| SEC24A | CYTL1 | 0.593877 | 3 | 0 | 3 |
| SEC24A | CYSRT1 | 0.591715 | 4 | 0 | 3 |
| SEC24A | PLS3 | 0.591233 | 6 | 0 | 4 |
For details and further investigation, click here
