| Full name: zinc finger and BTB domain containing 7A | Alias Symbol: FBI-1|LRF|DKFZp547O146|pokemon|ZNF857A | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 51341 | HGNC ID: HGNC:18078 | Ensembl Gene: ENSG00000178951 | OMIM ID: 605878 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZBTB7A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZBTB7A | 51341 | 226554_at | -0.5832 | 0.2576 | |
| GSE20347 | ZBTB7A | 51341 | 219186_at | -0.5162 | 0.0012 | |
| GSE23400 | ZBTB7A | 51341 | 222082_at | -0.2465 | 0.0000 | |
| GSE26886 | ZBTB7A | 51341 | 226554_at | -0.2747 | 0.2452 | |
| GSE29001 | ZBTB7A | 51341 | 219186_at | -0.5119 | 0.0521 | |
| GSE38129 | ZBTB7A | 51341 | 219186_at | -0.4834 | 0.0002 | |
| GSE45670 | ZBTB7A | 51341 | 226554_at | -0.2398 | 0.0923 | |
| GSE53622 | ZBTB7A | 51341 | 20726 | -0.4781 | 0.0000 | |
| GSE53624 | ZBTB7A | 51341 | 20726 | -0.2200 | 0.0035 | |
| GSE63941 | ZBTB7A | 51341 | 226554_at | -1.2709 | 0.0013 | |
| GSE77861 | ZBTB7A | 51341 | 226554_at | -0.3959 | 0.0859 | |
| GSE97050 | ZBTB7A | 51341 | A_33_P3283780 | -0.1252 | 0.5392 | |
| SRP007169 | ZBTB7A | 51341 | RNAseq | -1.4986 | 0.0001 | |
| SRP008496 | ZBTB7A | 51341 | RNAseq | -1.5296 | 0.0000 | |
| SRP064894 | ZBTB7A | 51341 | RNAseq | -0.6746 | 0.0008 | |
| SRP133303 | ZBTB7A | 51341 | RNAseq | -0.7702 | 0.0000 | |
| SRP159526 | ZBTB7A | 51341 | RNAseq | -1.0642 | 0.0000 | |
| SRP193095 | ZBTB7A | 51341 | RNAseq | -0.7028 | 0.0000 | |
| SRP219564 | ZBTB7A | 51341 | RNAseq | -0.8463 | 0.0003 | |
| TCGA | ZBTB7A | 51341 | RNAseq | -0.0965 | 0.0278 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ZBTB7A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZBTB7A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZBTB7A | 51341 | 5 | 3 | 22 | |
| GSE20123 | ZBTB7A | 51341 | 4 | 2 | 24 | |
| GSE43470 | ZBTB7A | 51341 | 1 | 9 | 33 | |
| GSE46452 | ZBTB7A | 51341 | 47 | 1 | 11 | |
| GSE47630 | ZBTB7A | 51341 | 5 | 7 | 28 | |
| GSE54993 | ZBTB7A | 51341 | 16 | 3 | 51 | |
| GSE54994 | ZBTB7A | 51341 | 6 | 16 | 31 | |
| GSE60625 | ZBTB7A | 51341 | 9 | 0 | 2 | |
| GSE74703 | ZBTB7A | 51341 | 1 | 6 | 29 | |
| GSE74704 | ZBTB7A | 51341 | 1 | 2 | 17 | |
| TCGA | ZBTB7A | 51341 | 11 | 18 | 67 |
Total number of gains: 106; Total number of losses: 67; Total Number of normals: 315.
Somatic mutations of ZBTB7A:
Generating mutation plots.
Highly correlated genes for ZBTB7A:
Showing top 20/971 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZBTB7A | APEH | 0.822407 | 3 | 0 | 3 |
| ZBTB7A | CGNL1 | 0.775916 | 3 | 0 | 3 |
| ZBTB7A | EDA2R | 0.763111 | 3 | 0 | 3 |
| ZBTB7A | ZNF441 | 0.744348 | 3 | 0 | 3 |
| ZBTB7A | PRDM10 | 0.74427 | 4 | 0 | 4 |
| ZBTB7A | SYN3 | 0.736471 | 4 | 0 | 3 |
| ZBTB7A | MAP2K3 | 0.73389 | 3 | 0 | 3 |
| ZBTB7A | HABP4 | 0.730571 | 3 | 0 | 3 |
| ZBTB7A | CCDC12 | 0.722899 | 5 | 0 | 5 |
| ZBTB7A | CPEB4 | 0.722336 | 6 | 0 | 6 |
| ZBTB7A | BRWD3 | 0.71183 | 3 | 0 | 3 |
| ZBTB7A | MPHOSPH8 | 0.710007 | 4 | 0 | 3 |
| ZBTB7A | THRB | 0.709536 | 4 | 0 | 4 |
| ZBTB7A | DIXDC1 | 0.706623 | 3 | 0 | 3 |
| ZBTB7A | TBL1Y | 0.704903 | 3 | 0 | 3 |
| ZBTB7A | GTF3C6 | 0.703696 | 3 | 0 | 3 |
| ZBTB7A | ZNF609 | 0.701816 | 3 | 0 | 3 |
| ZBTB7A | SLC46A2 | 0.701048 | 5 | 0 | 4 |
| ZBTB7A | KRT72 | 0.700063 | 3 | 0 | 3 |
| ZBTB7A | MRPL41 | 0.698085 | 3 | 0 | 3 |
For details and further investigation, click here
