| Full name: stimulated by retinoic acid 6 | Alias Symbol: FLJ12541 | ||
| Type: protein-coding gene | Cytoband: 15q24.1 | ||
| Entrez ID: 64220 | HGNC ID: HGNC:30650 | Ensembl Gene: ENSG00000137868 | OMIM ID: 610745 |
| Drug and gene relationship at DGIdb | |||
Expression of STRA6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | STRA6 | 64220 | 221701_s_at | 0.5839 | 0.0808 | |
| GSE20347 | STRA6 | 64220 | 221701_s_at | 0.4942 | 0.0769 | |
| GSE23400 | STRA6 | 64220 | 221701_s_at | 0.0053 | 0.9503 | |
| GSE26886 | STRA6 | 64220 | 221701_s_at | 0.9430 | 0.0000 | |
| GSE29001 | STRA6 | 64220 | 221701_s_at | 0.2319 | 0.2987 | |
| GSE38129 | STRA6 | 64220 | 221701_s_at | 0.6580 | 0.0007 | |
| GSE45670 | STRA6 | 64220 | 221701_s_at | 0.4891 | 0.0726 | |
| GSE53622 | STRA6 | 64220 | 21389 | -0.0138 | 0.8675 | |
| GSE53624 | STRA6 | 64220 | 21389 | -0.0392 | 0.6401 | |
| GSE63941 | STRA6 | 64220 | 221701_s_at | 0.9743 | 0.1454 | |
| GSE77861 | STRA6 | 64220 | 221701_s_at | 0.1646 | 0.6152 | |
| GSE97050 | STRA6 | 64220 | A_33_P3307500 | 0.0743 | 0.7664 | |
| SRP064894 | STRA6 | 64220 | RNAseq | 3.2008 | 0.0000 | |
| SRP133303 | STRA6 | 64220 | RNAseq | 3.1192 | 0.0000 | |
| SRP159526 | STRA6 | 64220 | RNAseq | 2.1826 | 0.0011 | |
| SRP219564 | STRA6 | 64220 | RNAseq | 3.0518 | 0.0001 | |
| TCGA | STRA6 | 64220 | RNAseq | 1.8339 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by STRA6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of STRA6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | STRA6 | 64220 | 9 | 0 | 21 | |
| GSE20123 | STRA6 | 64220 | 9 | 0 | 21 | |
| GSE43470 | STRA6 | 64220 | 4 | 6 | 33 | |
| GSE46452 | STRA6 | 64220 | 3 | 7 | 49 | |
| GSE47630 | STRA6 | 64220 | 8 | 10 | 22 | |
| GSE54993 | STRA6 | 64220 | 5 | 6 | 59 | |
| GSE54994 | STRA6 | 64220 | 5 | 7 | 41 | |
| GSE60625 | STRA6 | 64220 | 4 | 0 | 7 | |
| GSE74703 | STRA6 | 64220 | 4 | 3 | 29 | |
| GSE74704 | STRA6 | 64220 | 5 | 0 | 15 | |
| TCGA | STRA6 | 64220 | 13 | 15 | 68 |
Total number of gains: 69; Total number of losses: 54; Total Number of normals: 365.
Somatic mutations of STRA6:
Generating mutation plots.
Highly correlated genes for STRA6:
Showing top 20/250 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| STRA6 | SLC5A12 | 0.780581 | 3 | 0 | 3 |
| STRA6 | TSPAN1 | 0.729209 | 3 | 0 | 3 |
| STRA6 | KRT73 | 0.702103 | 3 | 0 | 3 |
| STRA6 | PPP1R35 | 0.664367 | 3 | 0 | 3 |
| STRA6 | MBOAT7 | 0.661591 | 4 | 0 | 4 |
| STRA6 | SERPINE1 | 0.659953 | 4 | 0 | 4 |
| STRA6 | KIAA1549 | 0.656779 | 3 | 0 | 3 |
| STRA6 | NIPSNAP1 | 0.653156 | 3 | 0 | 3 |
| STRA6 | BGN | 0.6522 | 3 | 0 | 3 |
| STRA6 | LINC00467 | 0.651637 | 3 | 0 | 3 |
| STRA6 | CASC15 | 0.64772 | 4 | 0 | 4 |
| STRA6 | SH3PXD2B | 0.647439 | 4 | 0 | 3 |
| STRA6 | ZNF236 | 0.646651 | 4 | 0 | 4 |
| STRA6 | ZNF827 | 0.642284 | 3 | 0 | 3 |
| STRA6 | EIF4EBP1 | 0.642144 | 3 | 0 | 3 |
| STRA6 | MYH9 | 0.641651 | 4 | 0 | 3 |
| STRA6 | APBA3 | 0.640155 | 4 | 0 | 3 |
| STRA6 | MPPED1 | 0.638264 | 3 | 0 | 3 |
| STRA6 | MPZL1 | 0.638101 | 4 | 0 | 4 |
| STRA6 | GPC4 | 0.636939 | 3 | 0 | 3 |
For details and further investigation, click here
