| Full name: acrosin binding protein | Alias Symbol: SP32|OY-TES-1|CT23 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 84519 | HGNC ID: HGNC:17195 | Ensembl Gene: ENSG00000111644 | OMIM ID: 608352 |
| Drug and gene relationship at DGIdb | |||
Expression of ACRBP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACRBP | 84519 | 223718_at | -0.1854 | 0.3794 | |
| GSE26886 | ACRBP | 84519 | 223717_s_at | -0.0933 | 0.6601 | |
| GSE45670 | ACRBP | 84519 | 223717_s_at | 0.1672 | 0.2468 | |
| GSE53622 | ACRBP | 84519 | 171832 | -0.0409 | 0.6720 | |
| GSE53624 | ACRBP | 84519 | 171832 | -0.1298 | 0.1673 | |
| GSE63941 | ACRBP | 84519 | 223717_s_at | 0.1870 | 0.3251 | |
| GSE77861 | ACRBP | 84519 | 223717_s_at | -0.0856 | 0.5555 | |
| GSE97050 | ACRBP | 84519 | A_33_P3396370 | -0.0131 | 0.9611 | |
| SRP133303 | ACRBP | 84519 | RNAseq | 0.2992 | 0.4106 | |
| SRP159526 | ACRBP | 84519 | RNAseq | 1.4691 | 0.0139 | |
| SRP219564 | ACRBP | 84519 | RNAseq | 1.4114 | 0.0374 | |
| TCGA | ACRBP | 84519 | RNAseq | -0.3102 | 0.2367 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ACRBP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACRBP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACRBP | 84519 | 9 | 3 | 18 | |
| GSE20123 | ACRBP | 84519 | 9 | 3 | 18 | |
| GSE43470 | ACRBP | 84519 | 8 | 3 | 32 | |
| GSE46452 | ACRBP | 84519 | 10 | 1 | 48 | |
| GSE47630 | ACRBP | 84519 | 12 | 2 | 26 | |
| GSE54993 | ACRBP | 84519 | 1 | 10 | 59 | |
| GSE54994 | ACRBP | 84519 | 10 | 2 | 41 | |
| GSE60625 | ACRBP | 84519 | 0 | 1 | 10 | |
| GSE74703 | ACRBP | 84519 | 7 | 2 | 27 | |
| GSE74704 | ACRBP | 84519 | 5 | 2 | 13 | |
| TCGA | ACRBP | 84519 | 40 | 6 | 50 |
Total number of gains: 111; Total number of losses: 35; Total Number of normals: 342.
Somatic mutations of ACRBP:
Generating mutation plots.
Highly correlated genes for ACRBP:
Showing top 20/171 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACRBP | RSL24D1 | 0.834365 | 3 | 0 | 3 |
| ACRBP | SAR1A | 0.803096 | 3 | 0 | 3 |
| ACRBP | VPS29 | 0.801283 | 3 | 0 | 3 |
| ACRBP | ACO2 | 0.798514 | 3 | 0 | 3 |
| ACRBP | KIR3DL2 | 0.78934 | 3 | 0 | 3 |
| ACRBP | AGXT | 0.784862 | 3 | 0 | 3 |
| ACRBP | COPS2 | 0.771686 | 3 | 0 | 3 |
| ACRBP | RORA | 0.768722 | 3 | 0 | 3 |
| ACRBP | SFTPA2 | 0.768224 | 3 | 0 | 3 |
| ACRBP | SYCE1 | 0.75505 | 3 | 0 | 3 |
| ACRBP | CD164 | 0.748327 | 3 | 0 | 3 |
| ACRBP | COPS7A | 0.737508 | 3 | 0 | 3 |
| ACRBP | SPRY1 | 0.736666 | 3 | 0 | 3 |
| ACRBP | KRTAP9-6 | 0.735122 | 3 | 0 | 3 |
| ACRBP | RIBC1 | 0.731275 | 3 | 0 | 3 |
| ACRBP | TNFRSF19 | 0.73004 | 3 | 0 | 3 |
| ACRBP | CD63 | 0.727964 | 3 | 0 | 3 |
| ACRBP | APOB | 0.724653 | 4 | 0 | 3 |
| ACRBP | C16orf90 | 0.723431 | 3 | 0 | 3 |
| ACRBP | RSPH9 | 0.722916 | 4 | 0 | 4 |
For details and further investigation, click here
