| Full name: claudin 9 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 9080 | HGNC ID: HGNC:2051 | Ensembl Gene: ENSG00000213937 | OMIM ID: 615799 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
CLDN9 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04530 | Tight junction |
Expression of CLDN9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CLDN9 | 9080 | 214635_at | -0.0386 | 0.8971 | |
| GSE20347 | CLDN9 | 9080 | 214635_at | -0.1279 | 0.0513 | |
| GSE23400 | CLDN9 | 9080 | 214635_at | -0.1519 | 0.0002 | |
| GSE26886 | CLDN9 | 9080 | 214635_at | 0.3619 | 0.0177 | |
| GSE29001 | CLDN9 | 9080 | 214635_at | 0.0464 | 0.7562 | |
| GSE38129 | CLDN9 | 9080 | 214635_at | -0.2055 | 0.0086 | |
| GSE45670 | CLDN9 | 9080 | 214635_at | -0.0713 | 0.5015 | |
| GSE53622 | CLDN9 | 9080 | 12990 | 0.1756 | 0.0343 | |
| GSE53624 | CLDN9 | 9080 | 12990 | 0.1181 | 0.1880 | |
| GSE63941 | CLDN9 | 9080 | 214635_at | 0.2757 | 0.4214 | |
| GSE77861 | CLDN9 | 9080 | 214635_at | -0.1295 | 0.4114 | |
| GSE97050 | CLDN9 | 9080 | A_33_P3352852 | 0.1641 | 0.6073 | |
| TCGA | CLDN9 | 9080 | RNAseq | -0.1763 | 0.7444 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CLDN9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CLDN9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CLDN9 | 9080 | 5 | 5 | 20 | |
| GSE20123 | CLDN9 | 9080 | 5 | 4 | 21 | |
| GSE43470 | CLDN9 | 9080 | 3 | 8 | 32 | |
| GSE46452 | CLDN9 | 9080 | 38 | 1 | 20 | |
| GSE47630 | CLDN9 | 9080 | 13 | 6 | 21 | |
| GSE54993 | CLDN9 | 9080 | 3 | 5 | 62 | |
| GSE54994 | CLDN9 | 9080 | 5 | 9 | 39 | |
| GSE60625 | CLDN9 | 9080 | 4 | 0 | 7 | |
| GSE74703 | CLDN9 | 9080 | 3 | 6 | 27 | |
| GSE74704 | CLDN9 | 9080 | 3 | 2 | 15 | |
| TCGA | CLDN9 | 9080 | 19 | 13 | 64 |
Total number of gains: 101; Total number of losses: 59; Total Number of normals: 328.
Somatic mutations of CLDN9:
Generating mutation plots.
Highly correlated genes for CLDN9:
Showing top 20/1465 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CLDN9 | YY2 | 0.890161 | 3 | 0 | 3 |
| CLDN9 | PLA2G2C | 0.886821 | 3 | 0 | 3 |
| CLDN9 | STRC | 0.868654 | 3 | 0 | 3 |
| CLDN9 | DCDC1 | 0.867593 | 3 | 0 | 3 |
| CLDN9 | MRGPRG | 0.861642 | 3 | 0 | 3 |
| CLDN9 | OR2T27 | 0.854586 | 3 | 0 | 3 |
| CLDN9 | SUN5 | 0.849417 | 3 | 0 | 3 |
| CLDN9 | PRSS38 | 0.835123 | 3 | 0 | 3 |
| CLDN9 | C9orf153 | 0.833893 | 3 | 0 | 3 |
| CLDN9 | CHST10 | 0.832831 | 3 | 0 | 3 |
| CLDN9 | OR2T1 | 0.832069 | 3 | 0 | 3 |
| CLDN9 | INSC | 0.829217 | 3 | 0 | 3 |
| CLDN9 | KRTAP10-12 | 0.826694 | 3 | 0 | 3 |
| CLDN9 | LBX2 | 0.814947 | 3 | 0 | 3 |
| CLDN9 | BBC3 | 0.808492 | 3 | 0 | 3 |
| CLDN9 | LHB | 0.807172 | 3 | 0 | 3 |
| CLDN9 | RENBP | 0.806086 | 3 | 0 | 3 |
| CLDN9 | NKX6-3 | 0.802608 | 4 | 0 | 4 |
| CLDN9 | C1QL2 | 0.802252 | 3 | 0 | 3 |
| CLDN9 | OR2A5 | 0.802175 | 3 | 0 | 3 |
For details and further investigation, click here
