| Full name: opioid growth factor receptor | Alias Symbol: 7-60 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 11054 | HGNC ID: HGNC:15768 | Ensembl Gene: ENSG00000060491 | OMIM ID: 606459 |
| Drug and gene relationship at DGIdb | |||
Expression of OGFR:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OGFR | 11054 | 202841_x_at | 0.4201 | 0.1750 | |
| GSE20347 | OGFR | 11054 | 202841_x_at | 0.0611 | 0.4717 | |
| GSE23400 | OGFR | 11054 | 202841_x_at | 0.0148 | 0.7869 | |
| GSE26886 | OGFR | 11054 | 202841_x_at | -0.1859 | 0.2049 | |
| GSE29001 | OGFR | 11054 | 202841_x_at | -0.2173 | 0.1896 | |
| GSE38129 | OGFR | 11054 | 202841_x_at | -0.0158 | 0.8349 | |
| GSE45670 | OGFR | 11054 | 202841_x_at | 0.2059 | 0.0466 | |
| GSE53622 | OGFR | 11054 | 54245 | 0.1491 | 0.0021 | |
| GSE53624 | OGFR | 11054 | 54245 | 0.1103 | 0.0342 | |
| GSE63941 | OGFR | 11054 | 202841_x_at | 0.6258 | 0.0437 | |
| GSE77861 | OGFR | 11054 | 202841_x_at | -0.0381 | 0.7159 | |
| GSE97050 | OGFR | 11054 | A_23_P28707 | 0.1053 | 0.5864 | |
| SRP007169 | OGFR | 11054 | RNAseq | -0.4722 | 0.4269 | |
| SRP008496 | OGFR | 11054 | RNAseq | -0.3018 | 0.3687 | |
| SRP064894 | OGFR | 11054 | RNAseq | 0.5467 | 0.0210 | |
| SRP133303 | OGFR | 11054 | RNAseq | 0.4238 | 0.0000 | |
| SRP159526 | OGFR | 11054 | RNAseq | 0.3526 | 0.3289 | |
| SRP193095 | OGFR | 11054 | RNAseq | 0.4758 | 0.0013 | |
| SRP219564 | OGFR | 11054 | RNAseq | 0.9218 | 0.0213 | |
| TCGA | OGFR | 11054 | RNAseq | 0.1010 | 0.0447 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OGFR expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OGFR:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OGFR | 11054 | 14 | 2 | 14 | |
| GSE20123 | OGFR | 11054 | 14 | 2 | 14 | |
| GSE43470 | OGFR | 11054 | 11 | 1 | 31 | |
| GSE46452 | OGFR | 11054 | 35 | 0 | 24 | |
| GSE47630 | OGFR | 11054 | 25 | 1 | 14 | |
| GSE54993 | OGFR | 11054 | 0 | 17 | 53 | |
| GSE54994 | OGFR | 11054 | 29 | 0 | 24 | |
| GSE60625 | OGFR | 11054 | 0 | 0 | 11 | |
| GSE74703 | OGFR | 11054 | 10 | 0 | 26 | |
| GSE74704 | OGFR | 11054 | 11 | 0 | 9 | |
| TCGA | OGFR | 11054 | 43 | 4 | 49 |
Total number of gains: 192; Total number of losses: 27; Total Number of normals: 269.
Somatic mutations of OGFR:
Generating mutation plots.
Highly correlated genes for OGFR:
Showing top 20/192 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OGFR | LCE1D | 0.701343 | 3 | 0 | 3 |
| OGFR | BATF2 | 0.69694 | 3 | 0 | 3 |
| OGFR | POU5F1B | 0.67279 | 3 | 0 | 3 |
| OGFR | CEP164 | 0.67115 | 4 | 0 | 3 |
| OGFR | C19orf44 | 0.669481 | 3 | 0 | 3 |
| OGFR | LINC00930 | 0.664778 | 3 | 0 | 3 |
| OGFR | MON1B | 0.660797 | 3 | 0 | 3 |
| OGFR | AATK | 0.659732 | 3 | 0 | 3 |
| OGFR | RAX | 0.656725 | 3 | 0 | 3 |
| OGFR | MARK4 | 0.64901 | 3 | 0 | 3 |
| OGFR | SYCN | 0.644054 | 4 | 0 | 4 |
| OGFR | STARD7-AS1 | 0.640047 | 3 | 0 | 3 |
| OGFR | HELZ2 | 0.637621 | 4 | 0 | 3 |
| OGFR | SPRED3 | 0.635901 | 3 | 0 | 3 |
| OGFR | LIPE | 0.63531 | 4 | 0 | 4 |
| OGFR | PHACTR3 | 0.631735 | 3 | 0 | 3 |
| OGFR | SLC6A2 | 0.62948 | 3 | 0 | 3 |
| OGFR | SH3BP2 | 0.62876 | 5 | 0 | 4 |
| OGFR | SLC25A53 | 0.625576 | 3 | 0 | 3 |
| OGFR | KCP | 0.624181 | 5 | 0 | 4 |
For details and further investigation, click here
