| Full name: transmembrane p24 trafficking protein family member 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 283578 | HGNC ID: HGNC:18633 | Ensembl Gene: ENSG00000100580 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMED8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMED8 | 283578 | 225343_at | 0.5651 | 0.1166 | |
| GSE26886 | TMED8 | 283578 | 225343_at | 0.6929 | 0.0001 | |
| GSE45670 | TMED8 | 283578 | 225343_at | 0.3772 | 0.0251 | |
| GSE53622 | TMED8 | 283578 | 10019 | 0.4016 | 0.0000 | |
| GSE53624 | TMED8 | 283578 | 73691 | 0.6184 | 0.0000 | |
| GSE63941 | TMED8 | 283578 | 225343_at | 0.7212 | 0.0805 | |
| GSE77861 | TMED8 | 283578 | 225343_at | 0.7798 | 0.0537 | |
| GSE97050 | TMED8 | 283578 | A_33_P3346157 | 0.1551 | 0.6844 | |
| SRP007169 | TMED8 | 283578 | RNAseq | 0.9378 | 0.0154 | |
| SRP008496 | TMED8 | 283578 | RNAseq | 1.5018 | 0.0000 | |
| SRP064894 | TMED8 | 283578 | RNAseq | 0.6339 | 0.0000 | |
| SRP133303 | TMED8 | 283578 | RNAseq | 0.6088 | 0.0000 | |
| SRP159526 | TMED8 | 283578 | RNAseq | 0.3076 | 0.1923 | |
| SRP193095 | TMED8 | 283578 | RNAseq | 0.5139 | 0.0000 | |
| SRP219564 | TMED8 | 283578 | RNAseq | 0.5248 | 0.1030 | |
| TCGA | TMED8 | 283578 | RNAseq | -0.0682 | 0.2215 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by TMED8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMED8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMED8 | 283578 | 8 | 3 | 19 | |
| GSE20123 | TMED8 | 283578 | 8 | 3 | 19 | |
| GSE43470 | TMED8 | 283578 | 8 | 3 | 32 | |
| GSE46452 | TMED8 | 283578 | 16 | 3 | 40 | |
| GSE47630 | TMED8 | 283578 | 11 | 8 | 21 | |
| GSE54993 | TMED8 | 283578 | 3 | 8 | 59 | |
| GSE54994 | TMED8 | 283578 | 19 | 4 | 30 | |
| GSE60625 | TMED8 | 283578 | 0 | 2 | 9 | |
| GSE74703 | TMED8 | 283578 | 7 | 3 | 26 | |
| GSE74704 | TMED8 | 283578 | 3 | 3 | 14 | |
| TCGA | TMED8 | 283578 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of TMED8:
Generating mutation plots.
Highly correlated genes for TMED8:
Showing top 20/1598 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMED8 | PKIG | 0.8348 | 3 | 0 | 3 |
| TMED8 | LGALS8 | 0.808864 | 3 | 0 | 3 |
| TMED8 | TCF7L2 | 0.808124 | 3 | 0 | 3 |
| TMED8 | NEDD9 | 0.796681 | 3 | 0 | 3 |
| TMED8 | DMTF1 | 0.792157 | 3 | 0 | 3 |
| TMED8 | PMPCB | 0.786917 | 3 | 0 | 3 |
| TMED8 | TSC22D1 | 0.780837 | 3 | 0 | 3 |
| TMED8 | PRKCA | 0.776747 | 3 | 0 | 3 |
| TMED8 | RAB8B | 0.775915 | 3 | 0 | 3 |
| TMED8 | ITGAE | 0.775805 | 3 | 0 | 3 |
| TMED8 | AZIN1 | 0.77536 | 3 | 0 | 3 |
| TMED8 | ZHX2 | 0.770805 | 3 | 0 | 3 |
| TMED8 | TARDBP | 0.770326 | 3 | 0 | 3 |
| TMED8 | ERH | 0.763385 | 6 | 0 | 6 |
| TMED8 | CPSF3 | 0.761963 | 3 | 0 | 3 |
| TMED8 | GDE1 | 0.761618 | 3 | 0 | 3 |
| TMED8 | CBLB | 0.757335 | 5 | 0 | 5 |
| TMED8 | MTERF3 | 0.75368 | 4 | 0 | 4 |
| TMED8 | PDS5B | 0.751568 | 4 | 0 | 4 |
| TMED8 | RPS21 | 0.750793 | 4 | 0 | 4 |
For details and further investigation, click here
