| Full name: solute carrier family 45 member 4 | Alias Symbol: KIAA1126 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 57210 | HGNC ID: HGNC:29196 | Ensembl Gene: ENSG00000022567 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SLC45A4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC45A4 | 57210 | 225597_at | 1.3852 | 0.0216 | |
| GSE26886 | SLC45A4 | 57210 | 225597_at | 1.3406 | 0.0001 | |
| GSE45670 | SLC45A4 | 57210 | 225597_at | 1.0277 | 0.0001 | |
| GSE53622 | SLC45A4 | 57210 | 16472 | 0.9160 | 0.0000 | |
| GSE53624 | SLC45A4 | 57210 | 16472 | 1.1669 | 0.0000 | |
| GSE63941 | SLC45A4 | 57210 | 225597_at | 0.0162 | 0.9774 | |
| GSE77861 | SLC45A4 | 57210 | 225597_at | 0.2843 | 0.1487 | |
| GSE97050 | SLC45A4 | A_21_P0005979 | -0.1866 | 0.5382 | ||
| SRP007169 | SLC45A4 | 57210 | RNAseq | 1.8686 | 0.0054 | |
| SRP008496 | SLC45A4 | 57210 | RNAseq | 1.3616 | 0.0065 | |
| SRP064894 | SLC45A4 | 57210 | RNAseq | 0.7819 | 0.0021 | |
| SRP133303 | SLC45A4 | 57210 | RNAseq | 0.5882 | 0.0023 | |
| SRP159526 | SLC45A4 | 57210 | RNAseq | 0.8953 | 0.0000 | |
| SRP193095 | SLC45A4 | 57210 | RNAseq | 0.2340 | 0.3617 | |
| TCGA | SLC45A4 | 57210 | RNAseq | -0.2264 | 0.0062 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SLC45A4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC45A4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC45A4 | 57210 | 17 | 0 | 13 | |
| GSE20123 | SLC45A4 | 57210 | 16 | 0 | 14 | |
| GSE43470 | SLC45A4 | 57210 | 21 | 2 | 20 | |
| GSE46452 | SLC45A4 | 57210 | 27 | 0 | 32 | |
| GSE47630 | SLC45A4 | 57210 | 24 | 0 | 16 | |
| GSE54993 | SLC45A4 | 57210 | 0 | 26 | 44 | |
| GSE54994 | SLC45A4 | 57210 | 39 | 1 | 13 | |
| GSE60625 | SLC45A4 | 57210 | 3 | 4 | 4 | |
| GSE74703 | SLC45A4 | 57210 | 19 | 1 | 16 | |
| GSE74704 | SLC45A4 | 57210 | 10 | 0 | 10 | |
| TCGA | SLC45A4 | 57210 | 65 | 2 | 29 |
Total number of gains: 241; Total number of losses: 36; Total Number of normals: 211.
Somatic mutations of SLC45A4:
Generating mutation plots.
Highly correlated genes for SLC45A4:
Showing top 20/1619 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC45A4 | FAM32A | 0.79745 | 3 | 0 | 3 |
| SLC45A4 | LGALS8 | 0.779991 | 3 | 0 | 3 |
| SLC45A4 | OTUD6B | 0.776286 | 3 | 0 | 3 |
| SLC45A4 | NCOA6 | 0.769348 | 3 | 0 | 3 |
| SLC45A4 | TFDP2 | 0.764985 | 4 | 0 | 4 |
| SLC45A4 | HELZ | 0.764802 | 3 | 0 | 3 |
| SLC45A4 | ATP6V1C1 | 0.757367 | 6 | 0 | 6 |
| SLC45A4 | U2SURP | 0.751523 | 5 | 0 | 5 |
| SLC45A4 | CHORDC1 | 0.748382 | 3 | 0 | 3 |
| SLC45A4 | EXOC6 | 0.742638 | 3 | 0 | 3 |
| SLC45A4 | GCSH | 0.74009 | 4 | 0 | 4 |
| SLC45A4 | RICTOR | 0.739535 | 3 | 0 | 3 |
| SLC45A4 | RAB13 | 0.737317 | 4 | 0 | 3 |
| SLC45A4 | DCUN1D2 | 0.736125 | 3 | 0 | 3 |
| SLC45A4 | TMEM97 | 0.735037 | 6 | 0 | 6 |
| SLC45A4 | FEZ2 | 0.734088 | 3 | 0 | 3 |
| SLC45A4 | CLCN7 | 0.733137 | 4 | 0 | 4 |
| SLC45A4 | PUF60 | 0.732695 | 7 | 0 | 7 |
| SLC45A4 | INTS8 | 0.732133 | 5 | 0 | 5 |
| SLC45A4 | PSMB6 | 0.732063 | 3 | 0 | 3 |
For details and further investigation, click here
