| Full name: PR/SET domain 15 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 63977 | HGNC ID: HGNC:13999 | Ensembl Gene: ENSG00000141956 | OMIM ID: 617692 |
| Drug and gene relationship at DGIdb | |||
Expression of PRDM15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRDM15 | 63977 | 230777_s_at | 0.5230 | 0.2989 | |
| GSE26886 | PRDM15 | 63977 | 230777_s_at | 0.0287 | 0.9060 | |
| GSE45670 | PRDM15 | 63977 | 230777_s_at | 0.4968 | 0.0001 | |
| GSE53622 | PRDM15 | 63977 | 7951 | 0.1124 | 0.1207 | |
| GSE53624 | PRDM15 | 63977 | 7951 | 0.2161 | 0.0003 | |
| GSE63941 | PRDM15 | 63977 | 230777_s_at | 0.0868 | 0.7786 | |
| GSE77861 | PRDM15 | 63977 | 230777_s_at | 0.1232 | 0.3043 | |
| GSE97050 | PRDM15 | 63977 | A_24_P194337 | 0.4219 | 0.1628 | |
| SRP007169 | PRDM15 | 63977 | RNAseq | 0.1855 | 0.6803 | |
| SRP008496 | PRDM15 | 63977 | RNAseq | 0.3202 | 0.3661 | |
| SRP064894 | PRDM15 | 63977 | RNAseq | 0.6693 | 0.0006 | |
| SRP133303 | PRDM15 | 63977 | RNAseq | 0.0349 | 0.8153 | |
| SRP159526 | PRDM15 | 63977 | RNAseq | 0.0221 | 0.9172 | |
| SRP193095 | PRDM15 | 63977 | RNAseq | 0.2328 | 0.0608 | |
| SRP219564 | PRDM15 | 63977 | RNAseq | -0.0671 | 0.8425 | |
| TCGA | PRDM15 | 63977 | RNAseq | 0.0788 | 0.1919 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PRDM15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRDM15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRDM15 | 63977 | 2 | 8 | 20 | |
| GSE20123 | PRDM15 | 63977 | 2 | 8 | 20 | |
| GSE43470 | PRDM15 | 63977 | 0 | 13 | 30 | |
| GSE46452 | PRDM15 | 63977 | 1 | 21 | 37 | |
| GSE47630 | PRDM15 | 63977 | 6 | 17 | 17 | |
| GSE54993 | PRDM15 | 63977 | 8 | 1 | 61 | |
| GSE54994 | PRDM15 | 63977 | 3 | 8 | 42 | |
| GSE60625 | PRDM15 | 63977 | 0 | 0 | 11 | |
| GSE74703 | PRDM15 | 63977 | 0 | 10 | 26 | |
| GSE74704 | PRDM15 | 63977 | 1 | 4 | 15 | |
| TCGA | PRDM15 | 63977 | 7 | 41 | 48 |
Total number of gains: 30; Total number of losses: 131; Total Number of normals: 327.
Somatic mutations of PRDM15:
Generating mutation plots.
Highly correlated genes for PRDM15:
Showing top 20/531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRDM15 | DPM2 | 0.839307 | 3 | 0 | 3 |
| PRDM15 | GPR107 | 0.817081 | 3 | 0 | 3 |
| PRDM15 | ZNF765 | 0.8025 | 3 | 0 | 3 |
| PRDM15 | INTS7 | 0.802064 | 3 | 0 | 3 |
| PRDM15 | DOCK6 | 0.794062 | 3 | 0 | 3 |
| PRDM15 | RHBDD1 | 0.792328 | 3 | 0 | 3 |
| PRDM15 | SRP9 | 0.79153 | 3 | 0 | 3 |
| PRDM15 | IFT80 | 0.789138 | 3 | 0 | 3 |
| PRDM15 | E2F3 | 0.786406 | 3 | 0 | 3 |
| PRDM15 | RPP38 | 0.771093 | 3 | 0 | 3 |
| PRDM15 | HNRNPF | 0.77039 | 3 | 0 | 3 |
| PRDM15 | CSNK1D | 0.769687 | 3 | 0 | 3 |
| PRDM15 | TCF19 | 0.761431 | 3 | 0 | 3 |
| PRDM15 | LGALS8 | 0.760263 | 3 | 0 | 3 |
| PRDM15 | THADA | 0.757229 | 3 | 0 | 3 |
| PRDM15 | SEC16A | 0.755212 | 4 | 0 | 4 |
| PRDM15 | DEDD | 0.753515 | 3 | 0 | 3 |
| PRDM15 | SGSH | 0.752319 | 3 | 0 | 3 |
| PRDM15 | GEN1 | 0.752044 | 3 | 0 | 3 |
| PRDM15 | LIMK1 | 0.749705 | 3 | 0 | 3 |
For details and further investigation, click here
