| Full name: HEAT repeat containing 6 | Alias Symbol: ABC1|FLJ22087 | ||
| Type: protein-coding gene | Cytoband: 17q23.1 | ||
| Entrez ID: 63897 | HGNC ID: HGNC:24076 | Ensembl Gene: ENSG00000068097 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HEATR6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEATR6 | 63897 | 218991_at | 0.4617 | 0.1515 | |
| GSE20347 | HEATR6 | 63897 | 218991_at | 0.5283 | 0.0000 | |
| GSE23400 | HEATR6 | 63897 | 218991_at | 0.1460 | 0.0004 | |
| GSE26886 | HEATR6 | 63897 | 218991_at | 1.3042 | 0.0000 | |
| GSE29001 | HEATR6 | 63897 | 218991_at | 0.5840 | 0.0025 | |
| GSE38129 | HEATR6 | 63897 | 218991_at | 0.3816 | 0.0001 | |
| GSE45670 | HEATR6 | 63897 | 218991_at | 0.3261 | 0.0575 | |
| GSE53622 | HEATR6 | 63897 | 14066 | 0.7772 | 0.0000 | |
| GSE53624 | HEATR6 | 63897 | 14066 | 0.8270 | 0.0000 | |
| GSE63941 | HEATR6 | 63897 | 218991_at | 0.0522 | 0.8852 | |
| GSE77861 | HEATR6 | 63897 | 218991_at | 0.3500 | 0.0152 | |
| GSE97050 | HEATR6 | 63897 | A_23_P77965 | 0.5187 | 0.1235 | |
| SRP007169 | HEATR6 | 63897 | RNAseq | 1.0571 | 0.0179 | |
| SRP008496 | HEATR6 | 63897 | RNAseq | 1.0672 | 0.0001 | |
| SRP064894 | HEATR6 | 63897 | RNAseq | 1.1609 | 0.0000 | |
| SRP133303 | HEATR6 | 63897 | RNAseq | 0.7433 | 0.0000 | |
| SRP159526 | HEATR6 | 63897 | RNAseq | 0.8400 | 0.0039 | |
| SRP193095 | HEATR6 | 63897 | RNAseq | 0.5558 | 0.0000 | |
| SRP219564 | HEATR6 | 63897 | RNAseq | 0.7844 | 0.0082 | |
| TCGA | HEATR6 | 63897 | RNAseq | 0.1688 | 0.0028 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by HEATR6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEATR6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEATR6 | 63897 | 5 | 1 | 24 | |
| GSE20123 | HEATR6 | 63897 | 5 | 1 | 24 | |
| GSE43470 | HEATR6 | 63897 | 5 | 0 | 38 | |
| GSE46452 | HEATR6 | 63897 | 32 | 0 | 27 | |
| GSE47630 | HEATR6 | 63897 | 7 | 1 | 32 | |
| GSE54993 | HEATR6 | 63897 | 2 | 5 | 63 | |
| GSE54994 | HEATR6 | 63897 | 9 | 5 | 39 | |
| GSE60625 | HEATR6 | 63897 | 4 | 0 | 7 | |
| GSE74703 | HEATR6 | 63897 | 5 | 0 | 31 | |
| GSE74704 | HEATR6 | 63897 | 4 | 1 | 15 | |
| TCGA | HEATR6 | 63897 | 28 | 7 | 61 |
Total number of gains: 106; Total number of losses: 21; Total Number of normals: 361.
Somatic mutations of HEATR6:
Generating mutation plots.
Highly correlated genes for HEATR6:
Showing top 20/1966 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEATR6 | TP53I13 | 0.816249 | 5 | 0 | 5 |
| HEATR6 | GLT8D1 | 0.808013 | 3 | 0 | 3 |
| HEATR6 | LGALS8 | 0.786134 | 3 | 0 | 3 |
| HEATR6 | SEMA4C | 0.780647 | 5 | 0 | 5 |
| HEATR6 | POLRMT | 0.778979 | 3 | 0 | 3 |
| HEATR6 | RUNDC1 | 0.76685 | 3 | 0 | 3 |
| HEATR6 | GNG10 | 0.766834 | 3 | 0 | 3 |
| HEATR6 | ALKBH6 | 0.763115 | 5 | 0 | 5 |
| HEATR6 | COMMD2 | 0.759048 | 4 | 0 | 4 |
| HEATR6 | ZNF766 | 0.757014 | 3 | 0 | 3 |
| HEATR6 | DOCK6 | 0.754673 | 3 | 0 | 3 |
| HEATR6 | TNFRSF1A | 0.753203 | 3 | 0 | 3 |
| HEATR6 | GPR161 | 0.7472 | 3 | 0 | 3 |
| HEATR6 | GLI3 | 0.743728 | 4 | 0 | 4 |
| HEATR6 | POLR2A | 0.743343 | 3 | 0 | 3 |
| HEATR6 | SLC35B2 | 0.743089 | 3 | 0 | 3 |
| HEATR6 | HES4 | 0.742244 | 3 | 0 | 3 |
| HEATR6 | DNTTIP1 | 0.741375 | 5 | 0 | 5 |
| HEATR6 | HIRA | 0.738186 | 3 | 0 | 3 |
| HEATR6 | NFIL3 | 0.736852 | 3 | 0 | 3 |
For details and further investigation, click here
