| Full name: nucleolar protein 7 | Alias Symbol: NOP27|RARG-1|dJ223E5.2 | ||
| Type: protein-coding gene | Cytoband: 6p23 | ||
| Entrez ID: 51406 | HGNC ID: HGNC:21040 | Ensembl Gene: ENSG00000225921 | OMIM ID: 611533 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOL7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOL7 | 51406 | 210097_s_at | 0.3149 | 0.4310 | |
| GSE20347 | NOL7 | 51406 | 210097_s_at | 0.3901 | 0.0188 | |
| GSE23400 | NOL7 | 51406 | 202882_x_at | 0.7077 | 0.0000 | |
| GSE26886 | NOL7 | 51406 | 210097_s_at | 1.0798 | 0.0000 | |
| GSE29001 | NOL7 | 51406 | 210097_s_at | 0.5582 | 0.0593 | |
| GSE38129 | NOL7 | 51406 | 210097_s_at | 0.2864 | 0.0122 | |
| GSE45670 | NOL7 | 51406 | 202882_x_at | 0.1633 | 0.3956 | |
| GSE53622 | NOL7 | 51406 | 10819 | 0.1777 | 0.0019 | |
| GSE53624 | NOL7 | 51406 | 10819 | 0.6350 | 0.0000 | |
| GSE63941 | NOL7 | 51406 | 202882_x_at | 0.4052 | 0.3290 | |
| GSE77861 | NOL7 | 51406 | 202882_x_at | 0.4352 | 0.0783 | |
| GSE97050 | NOL7 | 51406 | A_33_P3385361 | 0.1021 | 0.6192 | |
| SRP007169 | NOL7 | 51406 | RNAseq | 1.2843 | 0.0158 | |
| SRP008496 | NOL7 | 51406 | RNAseq | 0.6791 | 0.0757 | |
| SRP064894 | NOL7 | 51406 | RNAseq | 0.3487 | 0.0902 | |
| SRP133303 | NOL7 | 51406 | RNAseq | 0.3046 | 0.0097 | |
| SRP159526 | NOL7 | 51406 | RNAseq | 0.3431 | 0.0825 | |
| SRP193095 | NOL7 | 51406 | RNAseq | -0.0667 | 0.5605 | |
| SRP219564 | NOL7 | 51406 | RNAseq | 0.1911 | 0.5585 | |
| TCGA | NOL7 | 51406 | RNAseq | 0.1069 | 0.0723 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NOL7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOL7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOL7 | 51406 | 3 | 7 | 20 | |
| GSE20123 | NOL7 | 51406 | 3 | 7 | 20 | |
| GSE43470 | NOL7 | 51406 | 8 | 0 | 35 | |
| GSE46452 | NOL7 | 51406 | 1 | 10 | 48 | |
| GSE47630 | NOL7 | 51406 | 7 | 8 | 25 | |
| GSE54993 | NOL7 | 51406 | 1 | 1 | 68 | |
| GSE54994 | NOL7 | 51406 | 10 | 3 | 40 | |
| GSE60625 | NOL7 | 51406 | 0 | 1 | 10 | |
| GSE74703 | NOL7 | 51406 | 7 | 0 | 29 | |
| GSE74704 | NOL7 | 51406 | 2 | 3 | 15 | |
| TCGA | NOL7 | 51406 | 16 | 26 | 54 |
Total number of gains: 58; Total number of losses: 66; Total Number of normals: 364.
Somatic mutations of NOL7:
Generating mutation plots.
Highly correlated genes for NOL7:
Showing top 20/1457 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOL7 | ZNF584 | 0.820535 | 3 | 0 | 3 |
| NOL7 | PET117 | 0.804201 | 3 | 0 | 3 |
| NOL7 | SSBP4 | 0.802189 | 3 | 0 | 3 |
| NOL7 | ZNF234 | 0.775949 | 3 | 0 | 3 |
| NOL7 | SFSWAP | 0.774024 | 3 | 0 | 3 |
| NOL7 | NEK3 | 0.766427 | 3 | 0 | 3 |
| NOL7 | SFR1 | 0.761804 | 3 | 0 | 3 |
| NOL7 | LGALS8 | 0.756796 | 3 | 0 | 3 |
| NOL7 | TMEM237 | 0.745492 | 3 | 0 | 3 |
| NOL7 | ROMO1 | 0.738502 | 3 | 0 | 3 |
| NOL7 | COMMD7 | 0.737952 | 3 | 0 | 3 |
| NOL7 | ABHD16A | 0.736823 | 3 | 0 | 3 |
| NOL7 | CRTC2 | 0.730978 | 3 | 0 | 3 |
| NOL7 | EEF1E1 | 0.724286 | 11 | 0 | 10 |
| NOL7 | LYRM4 | 0.722724 | 12 | 0 | 11 |
| NOL7 | MRPL36 | 0.718509 | 4 | 0 | 3 |
| NOL7 | XAB2 | 0.718496 | 4 | 0 | 4 |
| NOL7 | TYW5 | 0.718008 | 3 | 0 | 3 |
| NOL7 | DEK | 0.715208 | 12 | 0 | 11 |
| NOL7 | TRMT10C | 0.713536 | 4 | 0 | 4 |
For details and further investigation, click here
