| Full name: lipoxygenase homology domains 1 | Alias Symbol: FLJ32670|LH2D1 | ||
| Type: protein-coding gene | Cytoband: 18q21.1 | ||
| Entrez ID: 125336 | HGNC ID: HGNC:26521 | Ensembl Gene: ENSG00000167210 | OMIM ID: 613072 |
| Drug and gene relationship at DGIdb | |||
Expression of LOXHD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LOXHD1 | 125336 | 241117_at | -0.0633 | 0.8474 | |
| GSE26886 | LOXHD1 | 125336 | 241117_at | 0.0841 | 0.4070 | |
| GSE45670 | LOXHD1 | 125336 | 241117_at | -0.0127 | 0.8967 | |
| GSE53622 | LOXHD1 | 125336 | 20269 | 0.1265 | 0.2698 | |
| GSE53624 | LOXHD1 | 125336 | 31358 | 0.4875 | 0.0000 | |
| GSE63941 | LOXHD1 | 125336 | 241117_at | 0.0233 | 0.8941 | |
| GSE77861 | LOXHD1 | 125336 | 241117_at | -0.0895 | 0.4888 | |
| TCGA | LOXHD1 | 125336 | RNAseq | -0.2327 | 0.6803 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LOXHD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LOXHD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LOXHD1 | 125336 | 1 | 8 | 21 | |
| GSE20123 | LOXHD1 | 125336 | 1 | 8 | 21 | |
| GSE43470 | LOXHD1 | 125336 | 0 | 4 | 39 | |
| GSE46452 | LOXHD1 | 125336 | 1 | 26 | 32 | |
| GSE47630 | LOXHD1 | 125336 | 5 | 20 | 15 | |
| GSE54993 | LOXHD1 | 125336 | 8 | 1 | 61 | |
| GSE54994 | LOXHD1 | 125336 | 3 | 14 | 36 | |
| GSE60625 | LOXHD1 | 125336 | 0 | 4 | 7 | |
| GSE74703 | LOXHD1 | 125336 | 0 | 3 | 33 | |
| GSE74704 | LOXHD1 | 125336 | 0 | 6 | 14 | |
| TCGA | LOXHD1 | 125336 | 15 | 39 | 42 |
Total number of gains: 34; Total number of losses: 133; Total Number of normals: 321.
Somatic mutations of LOXHD1:
Generating mutation plots.
Highly correlated genes for LOXHD1:
Showing top 20/74 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LOXHD1 | NKX2-1 | 0.746166 | 3 | 0 | 3 |
| LOXHD1 | RARA | 0.700438 | 3 | 0 | 3 |
| LOXHD1 | SARDH | 0.67653 | 3 | 0 | 3 |
| LOXHD1 | FAM131C | 0.672408 | 4 | 0 | 3 |
| LOXHD1 | GBX2 | 0.664592 | 3 | 0 | 3 |
| LOXHD1 | TMEM179 | 0.658147 | 3 | 0 | 3 |
| LOXHD1 | CCL24 | 0.655182 | 3 | 0 | 3 |
| LOXHD1 | DOC2B | 0.640298 | 3 | 0 | 3 |
| LOXHD1 | DOK1 | 0.637197 | 3 | 0 | 3 |
| LOXHD1 | ZMYND10 | 0.636197 | 3 | 0 | 3 |
| LOXHD1 | HNF1A | 0.633394 | 3 | 0 | 3 |
| LOXHD1 | KIAA1614 | 0.631742 | 4 | 0 | 3 |
| LOXHD1 | UBASH3B | 0.631443 | 3 | 0 | 3 |
| LOXHD1 | TCL1B | 0.629901 | 3 | 0 | 3 |
| LOXHD1 | SSPO | 0.628844 | 3 | 0 | 3 |
| LOXHD1 | SLC22A13 | 0.628375 | 3 | 0 | 3 |
| LOXHD1 | MATN4 | 0.627591 | 3 | 0 | 3 |
| LOXHD1 | AMN | 0.623234 | 3 | 0 | 3 |
| LOXHD1 | SNX8 | 0.619012 | 4 | 0 | 4 |
| LOXHD1 | GALNT9 | 0.61854 | 4 | 0 | 3 |
For details and further investigation, click here
