| Full name: sorting nexin 8 | Alias Symbol: Mvp1 | ||
| Type: protein-coding gene | Cytoband: 7p22.3 | ||
| Entrez ID: 29886 | HGNC ID: HGNC:14972 | Ensembl Gene: ENSG00000106266 | OMIM ID: 614905 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX8 | 29886 | 243135_x_at | 0.0227 | 0.9581 | |
| GSE26886 | SNX8 | 29886 | 243135_x_at | 0.2438 | 0.1864 | |
| GSE45670 | SNX8 | 29886 | 243135_x_at | 0.0192 | 0.8789 | |
| GSE53622 | SNX8 | 29886 | 10295 | 0.3294 | 0.0000 | |
| GSE53624 | SNX8 | 29886 | 10295 | 0.1970 | 0.0048 | |
| GSE63941 | SNX8 | 29886 | 243135_x_at | -0.0343 | 0.9030 | |
| GSE77861 | SNX8 | 29886 | 243135_x_at | -0.2177 | 0.2508 | |
| GSE97050 | SNX8 | 29886 | A_33_P3412722 | 0.4668 | 0.4535 | |
| SRP007169 | SNX8 | 29886 | RNAseq | -0.6602 | 0.1803 | |
| SRP008496 | SNX8 | 29886 | RNAseq | -0.3431 | 0.2673 | |
| SRP064894 | SNX8 | 29886 | RNAseq | 0.3617 | 0.0873 | |
| SRP133303 | SNX8 | 29886 | RNAseq | 0.5359 | 0.0000 | |
| SRP159526 | SNX8 | 29886 | RNAseq | 0.4830 | 0.1093 | |
| SRP193095 | SNX8 | 29886 | RNAseq | 0.3279 | 0.0636 | |
| SRP219564 | SNX8 | 29886 | RNAseq | 0.2436 | 0.5430 | |
| TCGA | SNX8 | 29886 | RNAseq | 0.3098 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNX8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX8 | 29886 | 14 | 0 | 16 | |
| GSE20123 | SNX8 | 29886 | 14 | 0 | 16 | |
| GSE43470 | SNX8 | 29886 | 7 | 3 | 33 | |
| GSE46452 | SNX8 | 29886 | 13 | 1 | 45 | |
| GSE47630 | SNX8 | 29886 | 10 | 1 | 29 | |
| GSE54993 | SNX8 | 29886 | 0 | 7 | 63 | |
| GSE54994 | SNX8 | 29886 | 18 | 6 | 29 | |
| GSE60625 | SNX8 | 29886 | 0 | 0 | 11 | |
| GSE74703 | SNX8 | 29886 | 7 | 2 | 27 | |
| GSE74704 | SNX8 | 29886 | 9 | 0 | 11 | |
| TCGA | SNX8 | 29886 | 56 | 6 | 34 |
Total number of gains: 148; Total number of losses: 26; Total Number of normals: 314.
Somatic mutations of SNX8:
Generating mutation plots.
Highly correlated genes for SNX8:
Showing top 20/159 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX8 | IGH | 0.750115 | 3 | 0 | 3 |
| SNX8 | NAPSA | 0.699469 | 3 | 0 | 3 |
| SNX8 | HMCN2 | 0.693391 | 3 | 0 | 3 |
| SNX8 | NKX2-1 | 0.681982 | 4 | 0 | 3 |
| SNX8 | NGB | 0.677236 | 3 | 0 | 3 |
| SNX8 | CASR | 0.67704 | 3 | 0 | 3 |
| SNX8 | VRTN | 0.668302 | 4 | 0 | 4 |
| SNX8 | RIN1 | 0.665501 | 3 | 0 | 3 |
| SNX8 | LINC01271 | 0.662688 | 3 | 0 | 3 |
| SNX8 | GBX2 | 0.662312 | 4 | 0 | 3 |
| SNX8 | OSBP2 | 0.66154 | 3 | 0 | 3 |
| SNX8 | ACY1 | 0.653205 | 3 | 0 | 3 |
| SNX8 | PLCB3 | 0.652749 | 3 | 0 | 3 |
| SNX8 | NAT8B | 0.651277 | 3 | 0 | 3 |
| SNX8 | YTHDF3-AS1 | 0.647547 | 3 | 0 | 3 |
| SNX8 | TSPAN16 | 0.64627 | 3 | 0 | 3 |
| SNX8 | PSG9 | 0.645447 | 3 | 0 | 3 |
| SNX8 | GRM1 | 0.642946 | 4 | 0 | 3 |
| SNX8 | TH | 0.636319 | 3 | 0 | 3 |
| SNX8 | DMRTA1 | 0.634445 | 4 | 0 | 3 |
For details and further investigation, click here
