| Full name: major facilitator superfamily domain containing 11 | Alias Symbol: FLJ22196|FLJ20226 | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 79157 | HGNC ID: HGNC:25458 | Ensembl Gene: ENSG00000092931 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MFSD11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MFSD11 | 79157 | 223242_s_at | -0.1447 | 0.8483 | |
| GSE20347 | MFSD11 | 79157 | 221192_x_at | 0.3050 | 0.0473 | |
| GSE23400 | MFSD11 | 79157 | 221192_x_at | 0.1028 | 0.0464 | |
| GSE26886 | MFSD11 | 79157 | 223242_s_at | -1.1769 | 0.0000 | |
| GSE29001 | MFSD11 | 79157 | 221192_x_at | 0.3497 | 0.0442 | |
| GSE38129 | MFSD11 | 79157 | 221192_x_at | 0.1485 | 0.3336 | |
| GSE45670 | MFSD11 | 79157 | 221192_x_at | 0.2618 | 0.0218 | |
| GSE63941 | MFSD11 | 79157 | 223242_s_at | -0.7320 | 0.1039 | |
| GSE77861 | MFSD11 | 79157 | 221192_x_at | 0.2491 | 0.3282 | |
| GSE97050 | MFSD11 | 79157 | A_23_P26704 | 0.3178 | 0.2533 | |
| SRP007169 | MFSD11 | 79157 | RNAseq | -0.8766 | 0.0420 | |
| SRP008496 | MFSD11 | 79157 | RNAseq | -1.0230 | 0.0000 | |
| SRP064894 | MFSD11 | 79157 | RNAseq | -0.0515 | 0.7101 | |
| SRP133303 | MFSD11 | 79157 | RNAseq | 0.1404 | 0.3410 | |
| SRP159526 | MFSD11 | 79157 | RNAseq | -0.3822 | 0.0803 | |
| SRP193095 | MFSD11 | 79157 | RNAseq | -0.4405 | 0.0000 | |
| SRP219564 | MFSD11 | 79157 | RNAseq | -0.3225 | 0.4048 | |
| TCGA | MFSD11 | 79157 | RNAseq | -0.0232 | 0.6549 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MFSD11 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MFSD11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MFSD11 | 79157 | 7 | 2 | 21 | |
| GSE20123 | MFSD11 | 79157 | 7 | 2 | 21 | |
| GSE43470 | MFSD11 | 79157 | 4 | 3 | 36 | |
| GSE46452 | MFSD11 | 79157 | 33 | 1 | 25 | |
| GSE47630 | MFSD11 | 79157 | 8 | 1 | 31 | |
| GSE54993 | MFSD11 | 79157 | 2 | 5 | 63 | |
| GSE54994 | MFSD11 | 79157 | 10 | 4 | 39 | |
| GSE60625 | MFSD11 | 79157 | 6 | 0 | 5 | |
| GSE74703 | MFSD11 | 79157 | 4 | 1 | 31 | |
| GSE74704 | MFSD11 | 79157 | 5 | 1 | 14 | |
| TCGA | MFSD11 | 79157 | 31 | 10 | 55 |
Total number of gains: 117; Total number of losses: 30; Total Number of normals: 341.
Somatic mutations of MFSD11:
Generating mutation plots.
Highly correlated genes for MFSD11:
Showing top 20/93 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MFSD11 | TMEM125 | 0.770224 | 3 | 0 | 3 |
| MFSD11 | PLA2G2D | 0.758372 | 4 | 0 | 3 |
| MFSD11 | RHBDL2 | 0.756824 | 4 | 0 | 4 |
| MFSD11 | USP49 | 0.741687 | 5 | 0 | 5 |
| MFSD11 | TACSTD2 | 0.740923 | 3 | 0 | 3 |
| MFSD11 | ZDHHC20 | 0.73781 | 3 | 0 | 3 |
| MFSD11 | PLA2G4D | 0.735054 | 3 | 0 | 3 |
| MFSD11 | CROT | 0.734399 | 4 | 0 | 4 |
| MFSD11 | CEACAM5 | 0.733721 | 3 | 0 | 3 |
| MFSD11 | FSCN3 | 0.717964 | 3 | 0 | 3 |
| MFSD11 | TMEM154 | 0.71158 | 3 | 0 | 3 |
| MFSD11 | CPNE6 | 0.708665 | 4 | 0 | 3 |
| MFSD11 | VPS33B | 0.7071 | 3 | 0 | 3 |
| MFSD11 | PPM1F | 0.689789 | 3 | 0 | 3 |
| MFSD11 | CDH26 | 0.68859 | 4 | 0 | 3 |
| MFSD11 | MYO5B | 0.687725 | 3 | 0 | 3 |
| MFSD11 | GATA2 | 0.687175 | 3 | 0 | 3 |
| MFSD11 | LINC00302 | 0.686948 | 6 | 0 | 4 |
| MFSD11 | THEG | 0.684898 | 3 | 0 | 3 |
| MFSD11 | PRSS27 | 0.683707 | 3 | 0 | 3 |
For details and further investigation, click here
