| Full name: keratin associated protein 5-8 | Alias Symbol: KRTAP5.8|UHSKerB|KRTAP5-2 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 57830 | HGNC ID: HGNC:23603 | Ensembl Gene: ENSG00000241233 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of KRTAP5-8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRTAP5-8 | 57830 | 208532_x_at | 0.0268 | 0.9174 | |
| GSE20347 | KRTAP5-8 | 57830 | 208532_x_at | -0.0264 | 0.8280 | |
| GSE23400 | KRTAP5-8 | 57830 | 208532_x_at | -0.0892 | 0.1122 | |
| GSE26886 | KRTAP5-8 | 57830 | 208532_x_at | -0.2695 | 0.0218 | |
| GSE29001 | KRTAP5-8 | 57830 | 208532_x_at | -0.2135 | 0.2130 | |
| GSE38129 | KRTAP5-8 | 57830 | 208532_x_at | -0.1691 | 0.1117 | |
| GSE45670 | KRTAP5-8 | 57830 | 208532_x_at | -0.1052 | 0.2658 | |
| GSE53622 | KRTAP5-8 | 57830 | 89017 | 0.5121 | 0.0217 | |
| GSE53624 | KRTAP5-8 | 57830 | 89017 | 0.6307 | 0.0004 | |
| GSE63941 | KRTAP5-8 | 57830 | 208532_x_at | 0.1422 | 0.3640 | |
| GSE77861 | KRTAP5-8 | 57830 | 208532_x_at | -0.1547 | 0.1450 | |
| GSE97050 | KRTAP5-8 | 57830 | A_33_P3237542 | 0.2262 | 0.3457 | |
| TCGA | KRTAP5-8 | 57830 | RNAseq | 1.1483 | 0.0886 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRTAP5-8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRTAP5-8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRTAP5-8 | 57830 | 11 | 6 | 13 | |
| GSE20123 | KRTAP5-8 | 57830 | 11 | 6 | 13 | |
| GSE43470 | KRTAP5-8 | 57830 | 7 | 4 | 32 | |
| GSE46452 | KRTAP5-8 | 57830 | 18 | 12 | 29 | |
| GSE47630 | KRTAP5-8 | 57830 | 11 | 9 | 20 | |
| GSE54993 | KRTAP5-8 | 57830 | 4 | 11 | 55 | |
| GSE54994 | KRTAP5-8 | 57830 | 11 | 12 | 30 | |
| GSE60625 | KRTAP5-8 | 57830 | 0 | 7 | 4 | |
| GSE74703 | KRTAP5-8 | 57830 | 6 | 3 | 27 | |
| GSE74704 | KRTAP5-8 | 57830 | 7 | 4 | 9 |
Total number of gains: 86; Total number of losses: 74; Total Number of normals: 232.
Somatic mutations of KRTAP5-8:
Generating mutation plots.
Highly correlated genes for KRTAP5-8:
Showing top 20/1070 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRTAP5-8 | SYT13 | 0.799661 | 3 | 0 | 3 |
| KRTAP5-8 | CPA2 | 0.799639 | 3 | 0 | 3 |
| KRTAP5-8 | AVP | 0.787534 | 4 | 0 | 3 |
| KRTAP5-8 | GDF5 | 0.781205 | 4 | 0 | 4 |
| KRTAP5-8 | GDAP1L1 | 0.76361 | 3 | 0 | 3 |
| KRTAP5-8 | GH2 | 0.738217 | 7 | 0 | 7 |
| KRTAP5-8 | IFNA17 | 0.731693 | 5 | 0 | 5 |
| KRTAP5-8 | CA5B | 0.730377 | 4 | 0 | 3 |
| KRTAP5-8 | CABLES1 | 0.729214 | 3 | 0 | 3 |
| KRTAP5-8 | GRK6 | 0.727638 | 5 | 0 | 5 |
| KRTAP5-8 | PHLDB1 | 0.726028 | 8 | 0 | 8 |
| KRTAP5-8 | KLF15 | 0.722939 | 4 | 0 | 4 |
| KRTAP5-8 | CCDC87 | 0.722589 | 5 | 0 | 5 |
| KRTAP5-8 | PRPS1L1 | 0.721591 | 6 | 0 | 6 |
| KRTAP5-8 | OR6A2 | 0.719927 | 5 | 0 | 4 |
| KRTAP5-8 | USP19 | 0.719089 | 3 | 0 | 3 |
| KRTAP5-8 | PRDM11 | 0.718939 | 5 | 0 | 5 |
| KRTAP5-8 | NTNG1 | 0.71496 | 4 | 0 | 4 |
| KRTAP5-8 | HAND1 | 0.71317 | 6 | 0 | 5 |
| KRTAP5-8 | MTAP | 0.710289 | 6 | 0 | 5 |
For details and further investigation, click here
