| Full name: LIM homeobox transcription factor 1 alpha | Alias Symbol: LMX1.1 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 4009 | HGNC ID: HGNC:6653 | Ensembl Gene: ENSG00000162761 | OMIM ID: 600298 |
| Drug and gene relationship at DGIdb | |||
Expression of LMX1A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMX1A | 4009 | 1553541_at | -0.0383 | 0.9138 | |
| GSE26886 | LMX1A | 4009 | 1553541_at | -0.0353 | 0.7346 | |
| GSE45670 | LMX1A | 4009 | 1553541_at | -0.0311 | 0.7742 | |
| GSE53622 | LMX1A | 4009 | 11329 | -0.2370 | 0.0559 | |
| GSE53624 | LMX1A | 4009 | 11329 | 0.0270 | 0.8306 | |
| GSE63941 | LMX1A | 4009 | 1553541_at | 0.2647 | 0.0773 | |
| GSE77861 | LMX1A | 4009 | 1553541_at | -0.0859 | 0.4400 | |
| TCGA | LMX1A | 4009 | RNAseq | -2.1841 | 0.0407 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LMX1A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMX1A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMX1A | 4009 | 10 | 2 | 18 | |
| GSE20123 | LMX1A | 4009 | 10 | 2 | 18 | |
| GSE43470 | LMX1A | 4009 | 7 | 2 | 34 | |
| GSE46452 | LMX1A | 4009 | 2 | 1 | 56 | |
| GSE47630 | LMX1A | 4009 | 14 | 0 | 26 | |
| GSE54993 | LMX1A | 4009 | 0 | 5 | 65 | |
| GSE54994 | LMX1A | 4009 | 16 | 0 | 37 | |
| GSE60625 | LMX1A | 4009 | 0 | 0 | 11 | |
| GSE74703 | LMX1A | 4009 | 7 | 2 | 27 | |
| GSE74704 | LMX1A | 4009 | 4 | 1 | 15 | |
| TCGA | LMX1A | 4009 | 43 | 3 | 50 |
Total number of gains: 113; Total number of losses: 18; Total Number of normals: 357.
Somatic mutations of LMX1A:
Generating mutation plots.
Highly correlated genes for LMX1A:
Showing top 20/34 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMX1A | MYL2 | 0.622278 | 3 | 0 | 3 |
| LMX1A | AMBN | 0.615245 | 4 | 0 | 3 |
| LMX1A | KLF14 | 0.612434 | 4 | 0 | 4 |
| LMX1A | DOK3 | 0.612048 | 4 | 0 | 4 |
| LMX1A | GJD4 | 0.607855 | 3 | 0 | 3 |
| LMX1A | LRRC52 | 0.605281 | 3 | 0 | 3 |
| LMX1A | SGSM1 | 0.60156 | 4 | 0 | 3 |
| LMX1A | SOX10 | 0.600554 | 4 | 0 | 4 |
| LMX1A | OR51M1 | 0.593274 | 4 | 0 | 3 |
| LMX1A | ABCA4 | 0.589039 | 3 | 0 | 3 |
| LMX1A | NXPH3 | 0.585024 | 3 | 0 | 3 |
| LMX1A | OR4D2 | 0.579255 | 5 | 0 | 4 |
| LMX1A | MIR4755 | 0.578175 | 4 | 0 | 4 |
| LMX1A | ANHX | 0.57282 | 4 | 0 | 3 |
| LMX1A | LCN15 | 0.568882 | 4 | 0 | 3 |
| LMX1A | GAB4 | 0.568064 | 4 | 0 | 3 |
| LMX1A | CACNG6 | 0.564293 | 5 | 0 | 3 |
| LMX1A | IFNL1 | 0.564185 | 4 | 0 | 3 |
| LMX1A | INSL3 | 0.560336 | 4 | 0 | 3 |
| LMX1A | RAX | 0.559379 | 4 | 0 | 3 |
For details and further investigation, click here
