| Full name: leucine rich repeat containing 73 | Alias Symbol: dJ337H4.2 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 221424 | HGNC ID: HGNC:21375 | Ensembl Gene: ENSG00000204052 | OMIM ID: |
Expression of LRRC73:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC73 | 221424 | 235935_at | 0.2915 | 0.1802 | |
| GSE26886 | LRRC73 | 221424 | 235935_at | 0.3306 | 0.0501 | |
| GSE45670 | LRRC73 | 221424 | 235935_at | 0.1545 | 0.2779 | |
| GSE53622 | LRRC73 | 221424 | 889 | 0.3766 | 0.0000 | |
| GSE53624 | LRRC73 | 221424 | 889 | 0.4012 | 0.0000 | |
| GSE63941 | LRRC73 | 221424 | 235935_at | -0.1531 | 0.6450 | |
| GSE77861 | LRRC73 | 221424 | 235935_at | -0.0932 | 0.3688 | |
| SRP159526 | LRRC73 | 221424 | RNAseq | 2.1960 | 0.0002 | |
| SRP219564 | LRRC73 | 221424 | RNAseq | 1.2269 | 0.0234 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LRRC73 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LRRC73:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC73 | 221424 | 7 | 0 | 23 | |
| GSE20123 | LRRC73 | 221424 | 7 | 0 | 23 | |
| GSE43470 | LRRC73 | 221424 | 6 | 0 | 37 | |
| GSE46452 | LRRC73 | 221424 | 2 | 9 | 48 | |
| GSE47630 | LRRC73 | 221424 | 8 | 4 | 28 | |
| GSE54993 | LRRC73 | 221424 | 3 | 2 | 65 | |
| GSE54994 | LRRC73 | 221424 | 11 | 4 | 38 | |
| GSE60625 | LRRC73 | 221424 | 0 | 1 | 10 | |
| GSE74703 | LRRC73 | 221424 | 6 | 0 | 30 | |
| GSE74704 | LRRC73 | 221424 | 3 | 0 | 17 | |
| TCGA | LRRC73 | 221424 | 20 | 12 | 64 |
Total number of gains: 73; Total number of losses: 32; Total Number of normals: 383.
Somatic mutations of LRRC73:
Generating mutation plots.
Highly correlated genes for LRRC73:
Showing top 20/47 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC73 | FMNL3 | 0.735788 | 3 | 0 | 3 |
| LRRC73 | PWP2 | 0.727113 | 3 | 0 | 3 |
| LRRC73 | SSTR5 | 0.723825 | 3 | 0 | 3 |
| LRRC73 | NRG1 | 0.67856 | 3 | 0 | 3 |
| LRRC73 | ZNF174 | 0.668437 | 4 | 0 | 3 |
| LRRC73 | HEYL | 0.637677 | 3 | 0 | 3 |
| LRRC73 | KLK14 | 0.635292 | 4 | 0 | 3 |
| LRRC73 | ZIC1 | 0.616364 | 4 | 0 | 3 |
| LRRC73 | LAMTOR2 | 0.614067 | 3 | 0 | 3 |
| LRRC73 | RASGEF1A | 0.61404 | 3 | 0 | 3 |
| LRRC73 | RITA1 | 0.613286 | 3 | 0 | 3 |
| LRRC73 | KCNJ10 | 0.613038 | 3 | 0 | 3 |
| LRRC73 | ZNF48 | 0.608392 | 3 | 0 | 3 |
| LRRC73 | B4GALT7 | 0.605423 | 4 | 0 | 3 |
| LRRC73 | DYRK3 | 0.602297 | 3 | 0 | 3 |
| LRRC73 | FOXJ1 | 0.596915 | 3 | 0 | 3 |
| LRRC73 | NOL4L | 0.590594 | 5 | 0 | 3 |
| LRRC73 | KCNE4 | 0.590467 | 3 | 0 | 3 |
| LRRC73 | MIIP | 0.589036 | 3 | 0 | 3 |
| LRRC73 | TGIF2 | 0.588069 | 4 | 0 | 3 |
For details and further investigation, click here
