KCNE4

 

Full name: potassium voltage-gated channel subfamily E regulatory subunit 4 Alias Symbol: MiRP3
Type: protein-coding gene Cytoband: 2q36.1
Entrez ID: 23704 HGNC ID: HGNC:6244 Ensembl Gene: ENSG00000152049 OMIM ID: 607775
Drug and gene relationship at DGIdb

 

Expression of KCNE4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KCNE4 23704 222379_at 0.2765 0.7755
GSE20347 KCNE4 23704 222379_at 0.0877 0.3461
GSE23400 KCNE4 23704 222379_at -0.0047 0.9346
GSE26886 KCNE4 23704 1552507_at 0.3380 0.0322
GSE29001 KCNE4 23704 222379_at 0.3179 0.3271
GSE38129 KCNE4 23704 222379_at -0.1924 0.5596
GSE45670 KCNE4 23704 222379_at -1.1184 0.0003
GSE53622 KCNE4 23704 50217 0.0797 0.6853
GSE53624 KCNE4 23704 94355 0.1524 0.2951
GSE63941 KCNE4 23704 1552507_at -0.5306 0.0003
GSE77861 KCNE4 23704 1552507_at -0.1250 0.3555
GSE97050 KCNE4 23704 A_33_P3246448 0.1398 0.7153
SRP007169 KCNE4 23704 RNAseq 2.6071 0.0002
SRP064894 KCNE4 23704 RNAseq 0.9345 0.0089
SRP133303 KCNE4 23704 RNAseq 0.4624 0.2404
SRP159526 KCNE4 23704 RNAseq -0.0222 0.9663
SRP193095 KCNE4 23704 RNAseq 0.6286 0.0388
SRP219564 KCNE4 23704 RNAseq -0.1735 0.8553
TCGA KCNE4 23704 RNAseq -0.6570 0.0004

Upregulated datasets: 1; Downregulated datasets: 1.  

 

Survival by KCNE4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KCNE4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KCNE4 23704 2 13 15
GSE20123 KCNE4 23704 2 13 15
GSE43470 KCNE4 23704 0 7 36
GSE46452 KCNE4 23704 0 5 54
GSE47630 KCNE4 23704 4 5 31
GSE54993 KCNE4 23704 1 2 67
GSE54994 KCNE4 23704 8 10 35
GSE60625 KCNE4 23704 3 0 8
GSE74703 KCNE4 23704 0 6 30
GSE74704 KCNE4 23704 2 7 11
TCGA KCNE4 23704 13 29 54

Total number of gains: 35; Total number of losses: 97; Total Number of normals: 356.  

 

Somatic mutations of KCNE4:

 

Generating mutation plots.

 

Highly correlated genes for KCNE4:

 

Showing top 20/758 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KCNE4C11orf960.734149404
KCNE4CCNA10.707912303
KCNE4GNG70.706195404
KCNE4LAMA40.703211011
KCNE4DPP40.700183404
KCNE4PMP220.688911009
KCNE4ADAMTS80.688386505
KCNE4JAM30.68554110010
KCNE4MAP40.684865403
KCNE4CLMP0.679452605
KCNE4STARD130.676418908
KCNE4SLIT30.674677503
KCNE4GREM20.674219303
KCNE4FAT40.674132504
KCNE4SH3RF30.673639404
KCNE4CRISPLD20.67190411010
KCNE4FAM151B0.671793303
KCNE4LINC012790.671167303
KCNE4KCNJ80.67068811011
KCNE4S1PR30.670143606

For details and further investigation, click here