| Full name: formin like 3 | Alias Symbol: DKFZp762B245|MGC45819|WBP3 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 91010 | HGNC ID: HGNC:23698 | Ensembl Gene: ENSG00000161791 | OMIM ID: 616288 |
| Drug and gene relationship at DGIdb | |||
Expression of FMNL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FMNL3 | 91010 | 230640_at | 0.7560 | 0.0319 | |
| GSE26886 | FMNL3 | 91010 | 230640_at | 0.8230 | 0.0018 | |
| GSE45670 | FMNL3 | 91010 | 230640_at | 0.1828 | 0.4041 | |
| GSE53622 | FMNL3 | 91010 | 112605 | 0.9433 | 0.0000 | |
| GSE53624 | FMNL3 | 91010 | 112605 | 1.2151 | 0.0000 | |
| GSE63941 | FMNL3 | 91010 | 230640_at | -0.2596 | 0.5829 | |
| GSE77861 | FMNL3 | 91010 | 232249_at | -0.1521 | 0.2628 | |
| GSE97050 | FMNL3 | 91010 | A_23_P379200 | 1.1263 | 0.0684 | |
| SRP007169 | FMNL3 | 91010 | RNAseq | 1.8633 | 0.0008 | |
| SRP008496 | FMNL3 | 91010 | RNAseq | 1.9324 | 0.0000 | |
| SRP064894 | FMNL3 | 91010 | RNAseq | 1.4538 | 0.0000 | |
| SRP133303 | FMNL3 | 91010 | RNAseq | 0.6365 | 0.0016 | |
| SRP159526 | FMNL3 | 91010 | RNAseq | 0.4568 | 0.2021 | |
| SRP193095 | FMNL3 | 91010 | RNAseq | 1.0752 | 0.0000 | |
| SRP219564 | FMNL3 | 91010 | RNAseq | 0.9360 | 0.0001 | |
| TCGA | FMNL3 | 91010 | RNAseq | 0.1095 | 0.1059 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by FMNL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FMNL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FMNL3 | 91010 | 7 | 1 | 22 | |
| GSE20123 | FMNL3 | 91010 | 7 | 1 | 22 | |
| GSE43470 | FMNL3 | 91010 | 3 | 0 | 40 | |
| GSE46452 | FMNL3 | 91010 | 8 | 1 | 50 | |
| GSE47630 | FMNL3 | 91010 | 11 | 2 | 27 | |
| GSE54993 | FMNL3 | 91010 | 0 | 5 | 65 | |
| GSE54994 | FMNL3 | 91010 | 4 | 1 | 48 | |
| GSE60625 | FMNL3 | 91010 | 0 | 0 | 11 | |
| GSE74703 | FMNL3 | 91010 | 3 | 0 | 33 | |
| GSE74704 | FMNL3 | 91010 | 5 | 1 | 14 | |
| TCGA | FMNL3 | 91010 | 16 | 11 | 69 |
Total number of gains: 64; Total number of losses: 23; Total Number of normals: 401.
Somatic mutations of FMNL3:
Generating mutation plots.
Highly correlated genes for FMNL3:
Showing top 20/828 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FMNL3 | LRRC8C | 0.799782 | 3 | 0 | 3 |
| FMNL3 | IL32 | 0.78675 | 4 | 0 | 4 |
| FMNL3 | BSG | 0.772724 | 4 | 0 | 4 |
| FMNL3 | NONO | 0.77237 | 4 | 0 | 4 |
| FMNL3 | FCGR3A | 0.763579 | 3 | 0 | 3 |
| FMNL3 | TK2 | 0.756545 | 3 | 0 | 3 |
| FMNL3 | PRELID1 | 0.750412 | 3 | 0 | 3 |
| FMNL3 | LIMK1 | 0.748664 | 5 | 0 | 5 |
| FMNL3 | PDIA5 | 0.746013 | 3 | 0 | 3 |
| FMNL3 | LRRC73 | 0.735788 | 3 | 0 | 3 |
| FMNL3 | RAB34 | 0.73294 | 3 | 0 | 3 |
| FMNL3 | EFHD2 | 0.728554 | 4 | 0 | 4 |
| FMNL3 | MPG | 0.727896 | 5 | 0 | 4 |
| FMNL3 | ADAMTS12 | 0.72753 | 7 | 0 | 6 |
| FMNL3 | INHBA | 0.727295 | 5 | 0 | 5 |
| FMNL3 | PPP5C | 0.723078 | 3 | 0 | 3 |
| FMNL3 | SLC35B2 | 0.722212 | 3 | 0 | 3 |
| FMNL3 | CMTM3 | 0.720508 | 7 | 0 | 6 |
| FMNL3 | UBA52 | 0.71889 | 3 | 0 | 3 |
| FMNL3 | ZNF707 | 0.716698 | 3 | 0 | 3 |
For details and further investigation, click here
