| Full name: TGFB induced factor homeobox 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 20q11.23 | ||
| Entrez ID: 60436 | HGNC ID: HGNC:15764 | Ensembl Gene: ENSG00000118707 | OMIM ID: 607294 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TGIF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TGIF2 | 60436 | 216262_s_at | 1.6324 | 0.0501 | |
| GSE20347 | TGIF2 | 60436 | 216262_s_at | 0.6596 | 0.0001 | |
| GSE23400 | TGIF2 | 60436 | 216262_s_at | 0.4237 | 0.0000 | |
| GSE26886 | TGIF2 | 60436 | 216262_s_at | 1.0965 | 0.0002 | |
| GSE29001 | TGIF2 | 60436 | 218724_s_at | 1.2650 | 0.0023 | |
| GSE38129 | TGIF2 | 60436 | 216262_s_at | 0.5917 | 0.0002 | |
| GSE45670 | TGIF2 | 60436 | 216262_s_at | 0.4270 | 0.0292 | |
| GSE53622 | TGIF2 | 60436 | 77798 | 1.2241 | 0.0000 | |
| GSE53624 | TGIF2 | 60436 | 77798 | 1.1418 | 0.0000 | |
| GSE63941 | TGIF2 | 60436 | 216262_s_at | 0.2144 | 0.7603 | |
| GSE77861 | TGIF2 | 60436 | 216262_s_at | -0.0367 | 0.8444 | |
| GSE97050 | TGIF2 | 60436 | A_23_P79794 | 0.3009 | 0.3481 | |
| SRP007169 | TGIF2 | 60436 | RNAseq | 1.4368 | 0.0025 | |
| SRP008496 | TGIF2 | 60436 | RNAseq | 1.8248 | 0.0000 | |
| SRP064894 | TGIF2 | 60436 | RNAseq | 0.6849 | 0.0017 | |
| SRP133303 | TGIF2 | 60436 | RNAseq | 0.5845 | 0.0001 | |
| SRP159526 | TGIF2 | 60436 | RNAseq | 1.4152 | 0.0098 | |
| SRP193095 | TGIF2 | 60436 | RNAseq | 0.9888 | 0.0000 | |
| SRP219564 | TGIF2 | 60436 | RNAseq | 0.6348 | 0.0072 | |
| TCGA | TGIF2 | 60436 | RNAseq | 0.2604 | 0.0074 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by TGIF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TGIF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TGIF2 | 60436 | 14 | 2 | 14 | |
| GSE20123 | TGIF2 | 60436 | 14 | 2 | 14 | |
| GSE43470 | TGIF2 | 60436 | 12 | 0 | 31 | |
| GSE46452 | TGIF2 | 60436 | 29 | 0 | 30 | |
| GSE47630 | TGIF2 | 60436 | 24 | 0 | 16 | |
| GSE54993 | TGIF2 | 60436 | 0 | 17 | 53 | |
| GSE54994 | TGIF2 | 60436 | 24 | 0 | 29 | |
| GSE60625 | TGIF2 | 60436 | 0 | 0 | 11 | |
| GSE74703 | TGIF2 | 60436 | 11 | 0 | 25 | |
| GSE74704 | TGIF2 | 60436 | 10 | 1 | 9 | |
| TCGA | TGIF2 | 60436 | 49 | 3 | 44 |
Total number of gains: 187; Total number of losses: 25; Total Number of normals: 276.
Somatic mutations of TGIF2:
Generating mutation plots.
Highly correlated genes for TGIF2:
Showing top 20/1602 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TGIF2 | NOC2L | 0.769245 | 3 | 0 | 3 |
| TGIF2 | ARFRP1 | 0.762416 | 3 | 0 | 3 |
| TGIF2 | NF1 | 0.752921 | 3 | 0 | 3 |
| TGIF2 | RAB34 | 0.749224 | 3 | 0 | 3 |
| TGIF2 | MAD2L2 | 0.748526 | 5 | 0 | 5 |
| TGIF2 | PYCR2 | 0.735024 | 3 | 0 | 3 |
| TGIF2 | DYRK2 | 0.732089 | 3 | 0 | 3 |
| TGIF2 | ZNF805 | 0.724688 | 3 | 0 | 3 |
| TGIF2 | SSBP4 | 0.72266 | 4 | 0 | 3 |
| TGIF2 | CRTC2 | 0.719104 | 3 | 0 | 3 |
| TGIF2 | PLOD3 | 0.715412 | 9 | 0 | 9 |
| TGIF2 | NADK | 0.715057 | 3 | 0 | 3 |
| TGIF2 | FLYWCH2 | 0.710789 | 3 | 0 | 3 |
| TGIF2 | GPR158 | 0.710583 | 5 | 0 | 5 |
| TGIF2 | HPS3 | 0.71038 | 4 | 0 | 4 |
| TGIF2 | ASB7 | 0.709961 | 3 | 0 | 3 |
| TGIF2 | PNKP | 0.70824 | 5 | 0 | 4 |
| TGIF2 | PSKH1 | 0.706847 | 3 | 0 | 3 |
| TGIF2 | ALG10B | 0.706824 | 3 | 0 | 3 |
| TGIF2 | MED30 | 0.704057 | 6 | 0 | 6 |
For details and further investigation, click here
