| Full name: lymphocyte specific protein 1 | Alias Symbol: WP34 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 4046 | HGNC ID: HGNC:6707 | Ensembl Gene: ENSG00000130592 | OMIM ID: 153432 |
| Drug and gene relationship at DGIdb | |||
LSP1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05152 | Tuberculosis |
Expression of LSP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LSP1 | 4046 | 203523_at | 0.5511 | 0.7359 | |
| GSE20347 | LSP1 | 4046 | 203523_at | 0.2221 | 0.3520 | |
| GSE23400 | LSP1 | 4046 | 203523_at | 0.0065 | 0.9516 | |
| GSE26886 | LSP1 | 4046 | 203523_at | 0.4602 | 0.0783 | |
| GSE29001 | LSP1 | 4046 | 203523_at | 0.0658 | 0.8105 | |
| GSE38129 | LSP1 | 4046 | 203523_at | -0.0661 | 0.8021 | |
| GSE45670 | LSP1 | 4046 | 203523_at | -0.4076 | 0.0057 | |
| GSE63941 | LSP1 | 4046 | 203523_at | 0.3281 | 0.4240 | |
| GSE77861 | LSP1 | 4046 | 203523_at | -0.3221 | 0.1438 | |
| GSE97050 | LSP1 | 4046 | A_33_P3369567 | 0.3342 | 0.2110 | |
| SRP007169 | LSP1 | 4046 | RNAseq | 0.0946 | 0.9008 | |
| SRP008496 | LSP1 | 4046 | RNAseq | -1.0069 | 0.0005 | |
| SRP064894 | LSP1 | 4046 | RNAseq | -0.3567 | 0.2487 | |
| SRP133303 | LSP1 | 4046 | RNAseq | -0.5433 | 0.0018 | |
| SRP159526 | LSP1 | 4046 | RNAseq | -1.2056 | 0.0655 | |
| SRP193095 | LSP1 | 4046 | RNAseq | -0.1386 | 0.5591 | |
| SRP219564 | LSP1 | 4046 | RNAseq | -0.0138 | 0.9772 | |
| TCGA | LSP1 | 4046 | RNAseq | -0.0679 | 0.5104 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LSP1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LSP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LSP1 | 4046 | 1 | 11 | 18 | |
| GSE20123 | LSP1 | 4046 | 1 | 12 | 17 | |
| GSE43470 | LSP1 | 4046 | 1 | 9 | 33 | |
| GSE46452 | LSP1 | 4046 | 7 | 8 | 44 | |
| GSE47630 | LSP1 | 4046 | 4 | 12 | 24 | |
| GSE54993 | LSP1 | 4046 | 3 | 1 | 66 | |
| GSE54994 | LSP1 | 4046 | 1 | 12 | 40 | |
| GSE60625 | LSP1 | 4046 | 0 | 0 | 11 | |
| GSE74703 | LSP1 | 4046 | 1 | 7 | 28 | |
| GSE74704 | LSP1 | 4046 | 0 | 8 | 12 | |
| TCGA | LSP1|ENSG00000130592.9 | NA | 8 | 39 | 49 |
Total number of gains: 27; Total number of losses: 119; Total Number of normals: 342.
Somatic mutations of LSP1:
Generating mutation plots.
Highly correlated genes for LSP1:
Showing top 20/266 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LSP1 | ANAPC5 | 0.809373 | 3 | 0 | 3 |
| LSP1 | FBXW9 | 0.754625 | 3 | 0 | 3 |
| LSP1 | ZNF578 | 0.752364 | 3 | 0 | 3 |
| LSP1 | C16orf46 | 0.751404 | 3 | 0 | 3 |
| LSP1 | ST8SIA6-AS1 | 0.739143 | 3 | 0 | 3 |
| LSP1 | ZIK1 | 0.737065 | 3 | 0 | 3 |
| LSP1 | SYNGR3 | 0.735039 | 4 | 0 | 3 |
| LSP1 | MYPOP | 0.725977 | 3 | 0 | 3 |
| LSP1 | MUL1 | 0.724822 | 3 | 0 | 3 |
| LSP1 | IFITM2 | 0.717208 | 3 | 0 | 3 |
| LSP1 | CSNK1D | 0.711919 | 4 | 0 | 3 |
| LSP1 | ZNF618 | 0.707539 | 3 | 0 | 3 |
| LSP1 | PRKCSH | 0.707097 | 4 | 0 | 3 |
| LSP1 | CCDC154 | 0.703686 | 3 | 0 | 3 |
| LSP1 | GYG2 | 0.701163 | 4 | 0 | 3 |
| LSP1 | SARM1 | 0.695929 | 3 | 0 | 3 |
| LSP1 | ANGPTL6 | 0.693536 | 3 | 0 | 3 |
| LSP1 | AGPAT3 | 0.685969 | 3 | 0 | 3 |
| LSP1 | URM1 | 0.684701 | 4 | 0 | 3 |
| LSP1 | SMG9 | 0.681156 | 4 | 0 | 3 |
For details and further investigation, click here
