| Full name: zinc finger protein interacting with K protein 1 | Alias Symbol: ZNF762 | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 284307 | HGNC ID: HGNC:33104 | Ensembl Gene: ENSG00000171649 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZIK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZIK1 | 284307 | 232774_x_at | 0.0507 | 0.9654 | |
| GSE26886 | ZIK1 | 284307 | 235773_at | -0.0382 | 0.8193 | |
| GSE45670 | ZIK1 | 284307 | 232774_x_at | -0.1095 | 0.2194 | |
| GSE53622 | ZIK1 | 284307 | 42417 | 0.0739 | 0.3252 | |
| GSE53624 | ZIK1 | 284307 | 42417 | 0.0426 | 0.4839 | |
| GSE63941 | ZIK1 | 284307 | 232774_x_at | 0.0500 | 0.9180 | |
| GSE77861 | ZIK1 | 284307 | 235773_at | -0.0259 | 0.8130 | |
| GSE97050 | ZIK1 | 284307 | A_33_P3278560 | -0.2460 | 0.2422 | |
| SRP064894 | ZIK1 | 284307 | RNAseq | -0.3269 | 0.1499 | |
| SRP133303 | ZIK1 | 284307 | RNAseq | -0.5367 | 0.0223 | |
| SRP159526 | ZIK1 | 284307 | RNAseq | -1.0026 | 0.0141 | |
| SRP193095 | ZIK1 | 284307 | RNAseq | 0.0991 | 0.5986 | |
| SRP219564 | ZIK1 | 284307 | RNAseq | -0.6689 | 0.1891 | |
| TCGA | ZIK1 | 284307 | RNAseq | -0.6529 | 0.0183 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZIK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZIK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZIK1 | 284307 | 2 | 5 | 23 | |
| GSE20123 | ZIK1 | 284307 | 2 | 4 | 24 | |
| GSE43470 | ZIK1 | 284307 | 2 | 9 | 32 | |
| GSE46452 | ZIK1 | 284307 | 45 | 1 | 13 | |
| GSE47630 | ZIK1 | 284307 | 8 | 6 | 26 | |
| GSE54993 | ZIK1 | 284307 | 18 | 4 | 48 | |
| GSE54994 | ZIK1 | 284307 | 5 | 12 | 36 | |
| GSE60625 | ZIK1 | 284307 | 9 | 0 | 2 | |
| GSE74703 | ZIK1 | 284307 | 2 | 6 | 28 | |
| GSE74704 | ZIK1 | 284307 | 2 | 1 | 17 | |
| TCGA | ZIK1 | 284307 | 20 | 15 | 61 |
Total number of gains: 115; Total number of losses: 63; Total Number of normals: 310.
Somatic mutations of ZIK1:
Generating mutation plots.
Highly correlated genes for ZIK1:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZIK1 | ZNF154 | 0.815232 | 3 | 0 | 3 |
| ZIK1 | TSR2 | 0.814387 | 3 | 0 | 3 |
| ZIK1 | HIC2 | 0.776128 | 3 | 0 | 3 |
| ZIK1 | SLC24A1 | 0.749395 | 3 | 0 | 3 |
| ZIK1 | LSP1 | 0.737065 | 3 | 0 | 3 |
| ZIK1 | SARM1 | 0.729462 | 3 | 0 | 3 |
| ZIK1 | CDAN1 | 0.72786 | 3 | 0 | 3 |
| ZIK1 | IKZF4 | 0.71138 | 4 | 0 | 4 |
| ZIK1 | FAM131B | 0.708445 | 4 | 0 | 3 |
| ZIK1 | ZNF263 | 0.694916 | 3 | 0 | 3 |
| ZIK1 | ZNF814 | 0.690501 | 3 | 0 | 3 |
| ZIK1 | AKT1S1 | 0.689802 | 3 | 0 | 3 |
| ZIK1 | ZNF174 | 0.685547 | 3 | 0 | 3 |
| ZIK1 | ZNF347 | 0.675545 | 5 | 0 | 5 |
| ZIK1 | PIP5K1B | 0.674197 | 3 | 0 | 3 |
| ZIK1 | MAST2 | 0.665023 | 4 | 0 | 3 |
| ZIK1 | ADRB1 | 0.664346 | 3 | 0 | 3 |
| ZIK1 | FBXW8 | 0.66065 | 4 | 0 | 3 |
| ZIK1 | RIC8B | 0.660316 | 3 | 0 | 3 |
| ZIK1 | PTPRU | 0.658506 | 4 | 0 | 3 |
For details and further investigation, click here
