PRKCSH

 

Full name: protein kinase C substrate 80K-H Alias Symbol: VASAP-60|GIIB
Type: protein-coding gene Cytoband: 19p13.2
Entrez ID: 5589 HGNC ID: HGNC:9411 Ensembl Gene: ENSG00000130175 OMIM ID: 177060
Drug and gene relationship at DGIdb

 

Expression of PRKCSH:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRKCSH 5589 214080_x_at 0.4564 0.3297
GSE20347 PRKCSH 5589 214080_x_at 0.2268 0.0248
GSE23400 PRKCSH 5589 214080_x_at 0.2125 0.0000
GSE26886 PRKCSH 5589 214080_x_at 0.8290 0.0006
GSE29001 PRKCSH 5589 214080_x_at 0.1593 0.7306
GSE38129 PRKCSH 5589 214080_x_at 0.1488 0.1495
GSE45670 PRKCSH 5589 214080_x_at 0.3346 0.0002
GSE53622 PRKCSH 5589 12292 0.2208 0.0001
GSE53624 PRKCSH 5589 12292 0.5509 0.0000
GSE63941 PRKCSH 5589 214080_x_at 1.2842 0.0010
GSE77861 PRKCSH 5589 214080_x_at 0.4506 0.1417
GSE97050 PRKCSH 5589 A_24_P396197 0.5187 0.1784
SRP007169 PRKCSH 5589 RNAseq 0.4273 0.2495
SRP008496 PRKCSH 5589 RNAseq 0.4683 0.0511
SRP064894 PRKCSH 5589 RNAseq 0.8845 0.0003
SRP133303 PRKCSH 5589 RNAseq 0.5030 0.0007
SRP159526 PRKCSH 5589 RNAseq 0.8946 0.0002
SRP193095 PRKCSH 5589 RNAseq 0.3270 0.0305
SRP219564 PRKCSH 5589 RNAseq 1.2486 0.0033
TCGA PRKCSH 5589 RNAseq 0.0845 0.0326

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by PRKCSH expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PRKCSH:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRKCSH 5589 4 2 24
GSE20123 PRKCSH 5589 3 1 26
GSE43470 PRKCSH 5589 2 6 35
GSE46452 PRKCSH 5589 47 1 11
GSE47630 PRKCSH 5589 4 7 29
GSE54993 PRKCSH 5589 16 3 51
GSE54994 PRKCSH 5589 6 13 34
GSE60625 PRKCSH 5589 9 0 2
GSE74703 PRKCSH 5589 2 4 30
GSE74704 PRKCSH 5589 0 1 19
TCGA PRKCSH 5589 16 12 68

Total number of gains: 109; Total number of losses: 50; Total Number of normals: 329.  

 

Somatic mutations of PRKCSH:

 

Generating mutation plots.

 

Highly correlated genes for PRKCSH:

 

Showing top 20/1305 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRKCSHTRAPPC10.801991404
PRKCSHRAB7A0.798985303
PRKCSHUBA10.798766404
PRKCSHRAVER10.783502706
PRKCSHNLK0.766457303
PRKCSHNAA600.761848403
PRKCSHFAM120A0.760647303
PRKCSHLRRC410.760143303
PRKCSHZNF8370.744198303
PRKCSHGGN0.741221303
PRKCSHSLC39A30.739217404
PRKCSHSEC16A0.737072303
PRKCSHPPP2R1A0.736455303
PRKCSHFBXO60.734801303
PRKCSHTERF20.73279404
PRKCSHZNF4510.729737303
PRKCSHSMARCD20.728886303
PRKCSHPHC20.726561303
PRKCSHARHGEF160.726295404
PRKCSHCSNK1D0.723021404

For details and further investigation, click here