| Full name: SMG9 nonsense mediated mRNA decay factor | Alias Symbol: FLJ12886 | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 56006 | HGNC ID: HGNC:25763 | Ensembl Gene: ENSG00000105771 | OMIM ID: 613176 |
Screen Evidence:
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Expression of SMG9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMG9 | 56006 | 221335_x_at | 0.3970 | 0.3774 | |
| GSE20347 | SMG9 | 56006 | 221335_x_at | 0.4783 | 0.0000 | |
| GSE23400 | SMG9 | 56006 | 221335_x_at | 0.2379 | 0.0000 | |
| GSE26886 | SMG9 | 56006 | 223188_at | 0.5211 | 0.0001 | |
| GSE29001 | SMG9 | 56006 | 221335_x_at | 0.2180 | 0.1525 | |
| GSE38129 | SMG9 | 56006 | 221335_x_at | 0.5298 | 0.0000 | |
| GSE45670 | SMG9 | 56006 | 223188_at | 0.3098 | 0.0004 | |
| GSE53622 | SMG9 | 56006 | 120027 | 0.7124 | 0.0000 | |
| GSE53624 | SMG9 | 56006 | 120027 | 0.9484 | 0.0000 | |
| GSE63941 | SMG9 | 56006 | 221335_x_at | 0.6490 | 0.0718 | |
| GSE77861 | SMG9 | 56006 | 223188_at | 0.0513 | 0.8310 | |
| GSE97050 | SMG9 | 56006 | A_23_P56127 | 0.4055 | 0.1239 | |
| SRP007169 | SMG9 | 56006 | RNAseq | 1.8731 | 0.0005 | |
| SRP008496 | SMG9 | 56006 | RNAseq | 1.1121 | 0.0120 | |
| SRP064894 | SMG9 | 56006 | RNAseq | 1.0076 | 0.0000 | |
| SRP133303 | SMG9 | 56006 | RNAseq | 0.3082 | 0.0213 | |
| SRP159526 | SMG9 | 56006 | RNAseq | 0.7642 | 0.0413 | |
| SRP193095 | SMG9 | 56006 | RNAseq | 0.3724 | 0.0003 | |
| SRP219564 | SMG9 | 56006 | RNAseq | 0.5487 | 0.0950 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SMG9 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMG9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMG9 | 56006 | 6 | 5 | 19 | |
| GSE20123 | SMG9 | 56006 | 5 | 4 | 21 | |
| GSE43470 | SMG9 | 56006 | 4 | 11 | 28 | |
| GSE46452 | SMG9 | 56006 | 45 | 1 | 13 | |
| GSE47630 | SMG9 | 56006 | 8 | 6 | 26 | |
| GSE54993 | SMG9 | 56006 | 17 | 4 | 49 | |
| GSE54994 | SMG9 | 56006 | 6 | 12 | 35 | |
| GSE60625 | SMG9 | 56006 | 9 | 0 | 2 | |
| GSE74703 | SMG9 | 56006 | 4 | 7 | 25 | |
| GSE74704 | SMG9 | 56006 | 4 | 2 | 14 | |
| TCGA | SMG9 | 56006 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 68; Total Number of normals: 298.
Somatic mutations of SMG9:
Generating mutation plots.
Highly correlated genes for SMG9:
Showing top 20/1450 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMG9 | MCM3AP | 0.799582 | 3 | 0 | 3 |
| SMG9 | SLC25A29 | 0.775214 | 3 | 0 | 3 |
| SMG9 | RPS19BP1 | 0.767139 | 3 | 0 | 3 |
| SMG9 | WDR25 | 0.765646 | 4 | 0 | 3 |
| SMG9 | LRRC41 | 0.754364 | 3 | 0 | 3 |
| SMG9 | SCNM1 | 0.750245 | 3 | 0 | 3 |
| SMG9 | EEF2 | 0.746884 | 3 | 0 | 3 |
| SMG9 | PPP1R16A | 0.744933 | 4 | 0 | 4 |
| SMG9 | PTCD1 | 0.744047 | 3 | 0 | 3 |
| SMG9 | PYCR2 | 0.736303 | 3 | 0 | 3 |
| SMG9 | RFNG | 0.736115 | 4 | 0 | 4 |
| SMG9 | ZNF805 | 0.735434 | 3 | 0 | 3 |
| SMG9 | COMMD7 | 0.731989 | 4 | 0 | 3 |
| SMG9 | ZNF503 | 0.728163 | 3 | 0 | 3 |
| SMG9 | NGF | 0.727077 | 3 | 0 | 3 |
| SMG9 | SLC35B2 | 0.720506 | 3 | 0 | 3 |
| SMG9 | ZNF707 | 0.718477 | 3 | 0 | 3 |
| SMG9 | HIBADH | 0.717872 | 4 | 0 | 4 |
| SMG9 | ZNF627 | 0.710305 | 3 | 0 | 3 |
| SMG9 | RICTOR | 0.710122 | 3 | 0 | 3 |
For details and further investigation, click here
