| Full name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 | Alias Symbol: B3GNT-2|BETA3GNT|B3GN-T2|B3GN-T1 | ||
| Type: protein-coding gene | Cytoband: 2p15 | ||
| Entrez ID: 10678 | HGNC ID: HGNC:15629 | Ensembl Gene: ENSG00000170340 | OMIM ID: 605581 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of B3GNT2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B3GNT2 | 10678 | 222870_s_at | 0.1075 | 0.8128 | |
| GSE20347 | B3GNT2 | 10678 | 219326_s_at | -0.4139 | 0.0408 | |
| GSE23400 | B3GNT2 | 10678 | 219326_s_at | -0.2163 | 0.0071 | |
| GSE26886 | B3GNT2 | 10678 | 222870_s_at | -0.9315 | 0.0002 | |
| GSE29001 | B3GNT2 | 10678 | 219326_s_at | -0.6645 | 0.0012 | |
| GSE38129 | B3GNT2 | 10678 | 219326_s_at | -0.1008 | 0.6442 | |
| GSE45670 | B3GNT2 | 10678 | 222870_s_at | -0.1969 | 0.0878 | |
| GSE53622 | B3GNT2 | 10678 | 80701 | -0.2189 | 0.0329 | |
| GSE53624 | B3GNT2 | 10678 | 80701 | -0.6349 | 0.0000 | |
| GSE63941 | B3GNT2 | 10678 | 222870_s_at | -0.1042 | 0.8417 | |
| GSE77861 | B3GNT2 | 10678 | 222870_s_at | -0.3535 | 0.1412 | |
| GSE97050 | B3GNT2 | 10678 | A_23_P500956 | -0.0470 | 0.8748 | |
| SRP007169 | B3GNT2 | 10678 | RNAseq | -1.0609 | 0.0302 | |
| SRP008496 | B3GNT2 | 10678 | RNAseq | -0.8330 | 0.0040 | |
| SRP064894 | B3GNT2 | 10678 | RNAseq | -0.6588 | 0.0205 | |
| SRP133303 | B3GNT2 | 10678 | RNAseq | -0.0009 | 0.9971 | |
| SRP159526 | B3GNT2 | 10678 | RNAseq | -0.3371 | 0.1663 | |
| SRP193095 | B3GNT2 | 10678 | RNAseq | -0.5606 | 0.0000 | |
| SRP219564 | B3GNT2 | 10678 | RNAseq | -0.4905 | 0.3318 | |
| TCGA | B3GNT2 | 10678 | RNAseq | 0.0445 | 0.4756 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by B3GNT2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B3GNT2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B3GNT2 | 10678 | 12 | 0 | 18 | |
| GSE20123 | B3GNT2 | 10678 | 12 | 0 | 18 | |
| GSE43470 | B3GNT2 | 10678 | 7 | 0 | 36 | |
| GSE46452 | B3GNT2 | 10678 | 2 | 3 | 54 | |
| GSE47630 | B3GNT2 | 10678 | 8 | 0 | 32 | |
| GSE54993 | B3GNT2 | 10678 | 0 | 6 | 64 | |
| GSE54994 | B3GNT2 | 10678 | 12 | 0 | 41 | |
| GSE60625 | B3GNT2 | 10678 | 0 | 3 | 8 | |
| GSE74703 | B3GNT2 | 10678 | 7 | 0 | 29 | |
| GSE74704 | B3GNT2 | 10678 | 10 | 0 | 10 | |
| TCGA | B3GNT2 | 10678 | 36 | 2 | 58 |
Total number of gains: 106; Total number of losses: 14; Total Number of normals: 368.
Somatic mutations of B3GNT2:
Generating mutation plots.
Highly correlated genes for B3GNT2:
Showing top 20/829 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B3GNT2 | EPG5 | 0.805663 | 3 | 0 | 3 |
| B3GNT2 | LYSMD3 | 0.763796 | 4 | 0 | 4 |
| B3GNT2 | ZCCHC8 | 0.757471 | 3 | 0 | 3 |
| B3GNT2 | PUS7L | 0.755374 | 3 | 0 | 3 |
| B3GNT2 | ABHD6 | 0.753396 | 3 | 0 | 3 |
| B3GNT2 | C6orf62 | 0.750149 | 3 | 0 | 3 |
| B3GNT2 | TRAPPC2 | 0.744342 | 3 | 0 | 3 |
| B3GNT2 | ZNF92 | 0.729115 | 3 | 0 | 3 |
| B3GNT2 | KIF21A | 0.726126 | 4 | 0 | 4 |
| B3GNT2 | TMEM117 | 0.725619 | 3 | 0 | 3 |
| B3GNT2 | ZNF506 | 0.723366 | 3 | 0 | 3 |
| B3GNT2 | SLC4A1AP | 0.71562 | 3 | 0 | 3 |
| B3GNT2 | ZNF649 | 0.710303 | 3 | 0 | 3 |
| B3GNT2 | PHYHD1 | 0.710282 | 3 | 0 | 3 |
| B3GNT2 | COPZ1 | 0.699301 | 3 | 0 | 3 |
| B3GNT2 | COG6 | 0.696655 | 4 | 0 | 3 |
| B3GNT2 | PHKB | 0.694195 | 4 | 0 | 3 |
| B3GNT2 | TMEM159 | 0.693256 | 3 | 0 | 3 |
| B3GNT2 | AIMP1 | 0.691749 | 3 | 0 | 3 |
| B3GNT2 | ZDHHC21 | 0.690348 | 4 | 0 | 3 |
For details and further investigation, click here
