NSG1

 

Full name: neuronal vesicle trafficking associated 1 Alias Symbol: P21|D4S234E|NEEP21
Type: protein-coding gene Cytoband: 4p16.3
Entrez ID: 27065 HGNC ID: HGNC:18790 Ensembl Gene: ENSG00000168824 OMIM ID: 607645
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of NSG1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NSG1 27065 209569_x_at -0.1932 0.8776
GSE20347 NSG1 27065 209569_x_at -1.5735 0.0000
GSE23400 NSG1 27065 209569_x_at -0.6079 0.0000
GSE26886 NSG1 27065 209570_s_at -1.1110 0.0041
GSE29001 NSG1 27065 209570_s_at -0.7005 0.2789
GSE38129 NSG1 27065 209569_x_at -0.7662 0.0163
GSE45670 NSG1 27065 209569_x_at -0.0581 0.9111
GSE63941 NSG1 27065 209569_x_at -2.0437 0.0890
GSE77861 NSG1 27065 209570_s_at -0.6674 0.0124
SRP007169 NSG1 27065 RNAseq -0.1664 0.8333
SRP064894 NSG1 27065 RNAseq -0.9918 0.0149
SRP133303 NSG1 27065 RNAseq -1.1369 0.0006
SRP159526 NSG1 27065 RNAseq -2.3928 0.0000
SRP193095 NSG1 27065 RNAseq -1.4771 0.0000
SRP219564 NSG1 27065 RNAseq -3.0550 0.0007

Upregulated datasets: 0; Downregulated datasets: 6.  


 

Copy number change of NSG1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NSG1 27065 0 17 13
GSE20123 NSG1 27065 0 17 13
GSE43470 NSG1 27065 0 17 26
GSE46452 NSG1 27065 1 36 22
GSE47630 NSG1 27065 1 19 20
GSE54993 NSG1 27065 10 0 60
GSE54994 NSG1 27065 3 12 38
GSE60625 NSG1 27065 0 0 11
GSE74703 NSG1 27065 0 13 23
GSE74704 NSG1 27065 0 9 11
TCGA NSG1 27065 7 47 42

Total number of gains: 22; Total number of losses: 187; Total Number of normals: 279.  


 

Somatic mutations of NSG1:

 

Generating mutation plots.

 

Highly correlated genes for NSG1:

 

Showing top 20/524 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NSG1ZHX10.761804303
NSG1SUMF10.753731303
NSG1MAN2B20.722495303
NSG1IL22RA10.721598505
NSG1ACPP0.690074505
NSG1ZBTB430.684998404
NSG1BTBD110.681691303
NSG1ERCC50.671287504
NSG1OXSR10.667008606
NSG1ALG140.659451303
NSG1BBOX10.649009706
NSG1SMIM140.648759403
NSG1MXD10.647198505
NSG1TLCD20.644909403
NSG1VPS4B0.643681505
NSG1ITM2B0.639817604
NSG1TOLLIP0.638864604
NSG1PMVK0.635346604
NSG1POF1B0.635188403
NSG1CAPG0.635171504

For details and further investigation, click here