MAPRE2

 

Full name: microtubule associated protein RP/EB family member 2 Alias Symbol: RP1|EB1|EB2
Type: protein-coding gene Cytoband: 18q12.1-q12.2
Entrez ID: 10982 HGNC ID: HGNC:6891 Ensembl Gene: ENSG00000166974 OMIM ID: 605789
Drug and gene relationship at DGIdb

 

Expression of MAPRE2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MAPRE2 10982 202501_at -0.0651 0.9542
GSE20347 MAPRE2 10982 202501_at 0.4520 0.0062
GSE23400 MAPRE2 10982 202501_at 0.0664 0.5030
GSE26886 MAPRE2 10982 202501_at -0.4332 0.1536
GSE29001 MAPRE2 10982 202501_at -0.0502 0.8469
GSE38129 MAPRE2 10982 202501_at 0.0414 0.8713
GSE45670 MAPRE2 10982 202501_at 0.0212 0.9400
GSE53622 MAPRE2 10982 39412 0.0844 0.4943
GSE53624 MAPRE2 10982 39412 0.3293 0.0015
GSE63941 MAPRE2 10982 202501_at 0.6079 0.2774
GSE77861 MAPRE2 10982 202501_at 0.7764 0.0038
GSE97050 MAPRE2 10982 A_23_P418015 0.0202 0.9513
SRP007169 MAPRE2 10982 RNAseq 1.3254 0.0340
SRP008496 MAPRE2 10982 RNAseq 0.7002 0.1629
SRP064894 MAPRE2 10982 RNAseq 0.5453 0.0186
SRP133303 MAPRE2 10982 RNAseq 0.4620 0.0754
SRP159526 MAPRE2 10982 RNAseq 0.1652 0.7002
SRP193095 MAPRE2 10982 RNAseq 0.2117 0.4118
SRP219564 MAPRE2 10982 RNAseq 0.3661 0.6347
TCGA MAPRE2 10982 RNAseq -0.3374 0.0000

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by MAPRE2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MAPRE2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MAPRE2 10982 2 5 23
GSE20123 MAPRE2 10982 2 5 23
GSE43470 MAPRE2 10982 0 3 40
GSE46452 MAPRE2 10982 1 25 33
GSE47630 MAPRE2 10982 5 20 15
GSE54993 MAPRE2 10982 7 1 62
GSE54994 MAPRE2 10982 1 16 36
GSE60625 MAPRE2 10982 0 4 7
GSE74703 MAPRE2 10982 0 3 33
GSE74704 MAPRE2 10982 1 4 15
TCGA MAPRE2 10982 15 37 44

Total number of gains: 34; Total number of losses: 123; Total Number of normals: 331.  

 

Somatic mutations of MAPRE2:

 

Generating mutation plots.

 

Highly correlated genes for MAPRE2:

 

Showing top 20/873 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MAPRE2GNA130.876327303
MAPRE2C20orf1940.788283303
MAPRE2GPC60.772959404
MAPRE2MSI20.769934303
MAPRE2ZNF3970.755403303
MAPRE2ANXA60.755046909
MAPRE2ATXN20.75431303
MAPRE2DENND4B0.751767303
MAPRE2FUNDC20.749561404
MAPRE2KCNJ80.743178808
MAPRE2ZNF7030.73078303
MAPRE2CNTLN0.725575403
MAPRE2DOCK110.721942404
MAPRE2ITPR30.720956303
MAPRE2TERF2IP0.718807404
MAPRE2PRELP0.715266303
MAPRE2DPYSL20.713689908
MAPRE2ZNF3430.710059303
MAPRE2SRRT0.70498303
MAPRE2SUCNR10.704966303

For details and further investigation, click here