DENND4B

 

Full name: DENN domain containing 4B Alias Symbol: 
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 9909 HGNC ID: HGNC:29044 Ensembl Gene: ENSG00000198837 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of DENND4B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DENND4B 9909 202860_at 0.6954 0.1159
GSE20347 DENND4B 9909 202860_at 0.6813 0.0000
GSE23400 DENND4B 9909 202860_at 0.3889 0.0000
GSE26886 DENND4B 9909 202860_at 0.7424 0.0001
GSE29001 DENND4B 9909 202860_at 0.5690 0.0016
GSE38129 DENND4B 9909 202860_at 0.5622 0.0000
GSE45670 DENND4B 9909 202860_at 0.4313 0.0027
GSE53622 DENND4B 9909 63226 0.3962 0.0000
GSE53624 DENND4B 9909 63226 0.5970 0.0000
GSE63941 DENND4B 9909 202860_at -0.0296 0.9524
GSE77861 DENND4B 9909 202860_at 0.8125 0.0011
GSE97050 DENND4B 9909 A_33_P3238573 0.2460 0.3429
SRP007169 DENND4B 9909 RNAseq 0.5136 0.1905
SRP008496 DENND4B 9909 RNAseq 0.7278 0.0042
SRP064894 DENND4B 9909 RNAseq 0.5087 0.0020
SRP133303 DENND4B 9909 RNAseq 0.1815 0.1216
SRP159526 DENND4B 9909 RNAseq 0.6824 0.0178
SRP193095 DENND4B 9909 RNAseq 0.6091 0.0000
SRP219564 DENND4B 9909 RNAseq 0.6423 0.0412
TCGA DENND4B 9909 RNAseq -0.0032 0.9455

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by DENND4B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of DENND4B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DENND4B 9909 14 0 16
GSE20123 DENND4B 9909 14 0 16
GSE43470 DENND4B 9909 7 2 34
GSE46452 DENND4B 9909 2 1 56
GSE47630 DENND4B 9909 14 0 26
GSE54993 DENND4B 9909 0 4 66
GSE54994 DENND4B 9909 16 0 37
GSE60625 DENND4B 9909 0 0 11
GSE74703 DENND4B 9909 6 1 29
GSE74704 DENND4B 9909 7 0 13
TCGA DENND4B 9909 38 2 56

Total number of gains: 118; Total number of losses: 10; Total Number of normals: 360.  

 

Somatic mutations of DENND4B:

 

Generating mutation plots.

 

Highly correlated genes for DENND4B:

 

Showing top 20/1723 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DENND4BSSBP40.803333505
DENND4BIPO90.785925808
DENND4BDUSP230.767973303
DENND4BZBED10.767354404
DENND4BSLC39A30.765445404
DENND4BSLC22A50.76039303
DENND4BDAG10.757751303
DENND4BADAR0.75466910010
DENND4BSRRT0.75285511011
DENND4BMAPRE20.751767303
DENND4BNEURL1B0.742003303
DENND4BC20orf1940.741019303
DENND4BITGAE0.738437303
DENND4BRRP360.731827303
DENND4BZNF8300.730025303
DENND4BGATAD2B0.725529505
DENND4BRAB230.725503303
DENND4BCBX50.724534303
DENND4BSTK32B0.723368303
DENND4BSCNM10.722682303

For details and further investigation, click here