| Full name: TERF2 interacting protein | Alias Symbol: RAP1 | ||
| Type: protein-coding gene | Cytoband: 16q23.1 | ||
| Entrez ID: 54386 | HGNC ID: HGNC:19246 | Ensembl Gene: ENSG00000166848 | OMIM ID: 605061 |
| Drug and gene relationship at DGIdb | |||
Expression of TERF2IP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TERF2IP | 54386 | 201174_s_at | 0.1239 | 0.7858 | |
| GSE20347 | TERF2IP | 54386 | 201174_s_at | 0.1573 | 0.1700 | |
| GSE23400 | TERF2IP | 54386 | 201174_s_at | 0.1609 | 0.0055 | |
| GSE26886 | TERF2IP | 54386 | 201174_s_at | -0.2869 | 0.2518 | |
| GSE29001 | TERF2IP | 54386 | 201174_s_at | 0.0820 | 0.6372 | |
| GSE38129 | TERF2IP | 54386 | 201174_s_at | 0.0609 | 0.7114 | |
| GSE45670 | TERF2IP | 54386 | 201174_s_at | -0.0097 | 0.9436 | |
| GSE53622 | TERF2IP | 54386 | 54178 | 0.0042 | 0.9495 | |
| GSE53624 | TERF2IP | 54386 | 54178 | 0.0460 | 0.5591 | |
| GSE63941 | TERF2IP | 54386 | 201174_s_at | -1.2619 | 0.0171 | |
| GSE77861 | TERF2IP | 54386 | 201174_s_at | 0.4221 | 0.0409 | |
| GSE97050 | TERF2IP | 54386 | A_23_P129704 | -0.0623 | 0.7743 | |
| SRP007169 | TERF2IP | 54386 | RNAseq | -0.5681 | 0.0884 | |
| SRP008496 | TERF2IP | 54386 | RNAseq | -0.6114 | 0.0154 | |
| SRP064894 | TERF2IP | 54386 | RNAseq | -0.3134 | 0.0155 | |
| SRP133303 | TERF2IP | 54386 | RNAseq | 0.2185 | 0.0008 | |
| SRP159526 | TERF2IP | 54386 | RNAseq | 0.0876 | 0.7097 | |
| SRP193095 | TERF2IP | 54386 | RNAseq | 0.0018 | 0.9872 | |
| SRP219564 | TERF2IP | 54386 | RNAseq | -0.1078 | 0.7275 | |
| TCGA | TERF2IP | 54386 | RNAseq | -0.0132 | 0.7775 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TERF2IP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TERF2IP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TERF2IP | 54386 | 4 | 0 | 26 | |
| GSE20123 | TERF2IP | 54386 | 4 | 0 | 26 | |
| GSE43470 | TERF2IP | 54386 | 2 | 7 | 34 | |
| GSE46452 | TERF2IP | 54386 | 37 | 2 | 20 | |
| GSE47630 | TERF2IP | 54386 | 11 | 8 | 21 | |
| GSE54993 | TERF2IP | 54386 | 2 | 4 | 64 | |
| GSE54994 | TERF2IP | 54386 | 8 | 10 | 35 | |
| GSE60625 | TERF2IP | 54386 | 4 | 0 | 7 | |
| GSE74703 | TERF2IP | 54386 | 2 | 5 | 29 | |
| GSE74704 | TERF2IP | 54386 | 2 | 0 | 18 | |
| TCGA | TERF2IP | 54386 | 24 | 15 | 57 |
Total number of gains: 100; Total number of losses: 51; Total Number of normals: 337.
Somatic mutations of TERF2IP:
Generating mutation plots.
Highly correlated genes for TERF2IP:
Showing top 20/498 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TERF2IP | ARL13B | 0.787605 | 3 | 0 | 3 |
| TERF2IP | PLEKHM3 | 0.767326 | 3 | 0 | 3 |
| TERF2IP | SGTB | 0.747009 | 3 | 0 | 3 |
| TERF2IP | ZMYM6 | 0.746898 | 4 | 0 | 4 |
| TERF2IP | ZCCHC17 | 0.744563 | 3 | 0 | 3 |
| TERF2IP | RAD21 | 0.741115 | 3 | 0 | 3 |
| TERF2IP | MAP4K4 | 0.740508 | 3 | 0 | 3 |
| TERF2IP | MRPL45 | 0.73597 | 3 | 0 | 3 |
| TERF2IP | LIPT1 | 0.733121 | 3 | 0 | 3 |
| TERF2IP | PSMD3 | 0.726895 | 3 | 0 | 3 |
| TERF2IP | NIPA1 | 0.724661 | 3 | 0 | 3 |
| TERF2IP | ARHGEF33 | 0.723671 | 3 | 0 | 3 |
| TERF2IP | SNX25 | 0.721771 | 3 | 0 | 3 |
| TERF2IP | MAPRE2 | 0.718807 | 4 | 0 | 4 |
| TERF2IP | RNF138 | 0.718119 | 3 | 0 | 3 |
| TERF2IP | MAML1 | 0.713789 | 3 | 0 | 3 |
| TERF2IP | RUNDC1 | 0.71297 | 3 | 0 | 3 |
| TERF2IP | MED10 | 0.712341 | 3 | 0 | 3 |
| TERF2IP | FITM2 | 0.712197 | 3 | 0 | 3 |
| TERF2IP | C17orf75 | 0.710957 | 4 | 0 | 3 |
For details and further investigation, click here
